| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 17 | - | The Darjeeling Limited | $6,144 | - | 1 | - | $6,144 | $6,144 | 1 | N/A | true | false |
| 1 | - | The Eye | $143,831 | - | 30 | - | $4,794 | $143,831 | 1 | N/A | true | false |
| 3 | - | The Bucket List | $85,220 | - | 20 | - | $4,261 | $85,220 | 1 | N/A | true | false |
| 6 | - | The Mist | $76,875 | - | 20 | - | $3,843 | $76,875 | 1 | N/A | true | false |
| 2 | 2 | 27 Dresses | $93,638 | -52.7% | 28 | - | $3,344 | $327,007 | 2 | N/A | false | false |
| 10 | 8 | In the Name of the King: A Dungeon Siege Tale | $47,117 | -45.7% | 20 | - | $2,355 | $159,950 | 2 | N/A | false | false |
| 4 | 1 | Cloverfield | $81,478 | -64.7% | 35 | - | $2,327 | $350,600 | 2 | N/A | false | false |
| 8 | 5 | Alvin and the Chipmunks | $62,567 | -39.5% | 30 | - | $2,085 | $615,636 | 4 | N/A | false | false |
| 11 | 9 | Saw IV | $39,678 | -46.7% | 20 | - | $1,983 | $119,033 | 2 | N/A | false | false |
| 5 | - | Good Luck Chuck | $78,734 | - | 43 | - | $1,831 | $91,097 | 1 | N/A | true | false |
| 7 | 4 | Rambo | $75,788 | -28.6% | 45 | - | $1,684 | $549,083 | 3 | N/A | false | false |
| 13 | 6 | One Missed Call | $37,411 | -62.5% | 25 | - | $1,496 | $160,094 | 2 | N/A | false | false |
| 9 | 3 | Aliens vs. Predator: Requiem | $60,653 | -65.9% | 42 | -13 | $1,444 | $824,843 | 3 | N/A | false | false |
| 16 | 14 | Sweeney Todd: The Demon Barber of Fleet Street | $12,742 | +22.4% | 13 | - | $980 | $223,234 | 4 | N/A | false | false |
| 12 | 7 | National Treasure: Book of Secrets | $38,691 | -61.1% | 40 | -34 | $967 | $2,342,937 | 5 | N/A | false | false |
| 15 | 11 | American Gangster | $13,005 | -40.9% | 21 | -3 | $619 | $126,926 | 3 | N/A | false | false |
| 14 | 10 | I Am Legend | $16,386 | -74.2% | 32 | -27 | $512 | $1,505,903 | 5 | N/A | false | false |
| 18 | 13 | The Heartbreak Kid | $2,322 | -81.3% | 5 | -12 | $464 | $171,334 | 4 | N/A | false | false |
| 19 | 16 | Bee Movie | $798 | -71.7% | 4 | -10 | $199 | $314,187 | 5 | N/A | false | false |
