| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | National Treasure: Book of Secrets | $161,524 | -25.3% | 82 | -7 | $1,969 | $1,001,291 | 3 | Ster-Kinekor Pictures | false | false |
| 2 | - | The Bucket List | $138,143 | - | 39 | - | $3,542 | $138,143 | 1 | NuMetro Distribution | true | false |
| 3 | - | Good Luck Chuck | $96,181 | - | 31 | - | $3,102 | $96,181 | 1 | United International Pictures | true | false |
| 4 | 2 | I Am Legend | $81,071 | -12.8% | 66 | - | $1,228 | $1,732,883 | 5 | NuMetro Distribution | false | false |
| 5 | 4 | Alvin and the Chipmunks | $59,928 | -7.3% | 53 | - | $1,130 | $869,722 | 5 | NuMetro Distribution | false | false |
| 6 | 3 | Saw IV | $58,508 | -36.7% | 40 | - | $1,462 | $185,758 | 2 | Ster-Kinekor Pictures | false | false |
| 7 | 6 | Enchanted | $42,310 | -30.1% | 55 | -13 | $769 | $1,394,064 | 6 | Ster-Kinekor Pictures | false | false |
| 8 | - | Arthur and the Invisibles | $38,989 | - | 30 | - | $1,299 | $38,989 | 1 | Ster-Kinekor Pictures | true | false |
| 9 | 5 | Elizabeth: The Golden Age | $38,409 | -40.5% | 38 | +10 | $1,010 | $132,369 | 2 | United International Pictures | false | false |
| 10 | 7 | We Own the Night | $21,118 | -52.9% | 29 | -28 | $728 | $458,007 | 4 | United International Pictures | false | false |
| 11 | 12 | Hitman | $17,375 | -17.7% | 29 | -2 | $599 | $717,364 | 7 | NuMetro Distribution | false | false |
| 12 | 8 | Griffin & Phoenix | $17,155 | -40.6% | 33 | - | $519 | $65,606 | 2 | NuMetro Distribution | false | false |
| 13 | - | Gone Baby Gone | $16,204 | - | 8 | - | $2,025 | $16,204 | 1 | Ster-Kinekor Pictures | true | false |
| 14 | - | Into the Wild | $14,317 | - | 10 | - | $1,431 | $14,317 | 1 | United International Pictures | true | false |
| 15 | 10 | American Gangster | $13,731 | -39.7% | 19 | -13 | $722 | $815,145 | 8 | United International Pictures | false | false |
| 16 | - | Talk to Me | $12,469 | - | 26 | - | $479 | $12,469 | 1 | United International Pictures | true | false |
| 17 | 14 | August Rush | $11,797 | -32.9% | 4 | -12 | $2,949 | $258,295 | 5 | NuMetro Distribution | false | false |
| 18 | 13 | Aliens vs. Predator: Requiem | $11,608 | -37.6% | 21 | -11 | $552 | $257,157 | 4 | NuMetro Distribution | false | false |
| 19 | 9 | Martian Child | $11,068 | -60.1% | 25 | - | $442 | $49,989 | 2 | NuMetro Distribution | false | false |
| 20 | 16 | The Jane Austen Book Club | $10,321 | -37.3% | 9 | -3 | $1,146 | $146,804 | 4 | Ster-Kinekor Pictures | false | false |
| 21 | 11 | Bee Movie | $8,662 | -59.9% | 25 | -21 | $346 | $1,391,377 | 7 | United International Pictures | false | false |
| 22 | 18 | La Vie En Rose | $7,606 | -7.1% | 6 | - | $1,267 | $137,081 | 7 | Ster-Kinekor Pictures | false | false |
| 23 | 21 | This Christmas | $4,579 | +23.5% | 8 | -2 | $572 | $166,594 | 6 | Ster-Kinekor Pictures | false | false |
| 24 | 22 | 30 Days of Night | $1,817 | -34% | 4 | -3 | $454 | $286,778 | 7 | United International Pictures | false | false |
| 25 | 23 | The Heartbreak Kid | $1,351 | -44% | 4 | -1 | $337 | $912,922 | 11 | United International Pictures | false | false |
