| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Cloverfield | $46,146,546 | - | 3,411 | - | $13,528 | $46,146,546 | 1 | Paramount Pictures | true | false |
| 2 | - | 27 Dresses | $27,442,040 | - | 3,057 | - | $8,976 | $27,442,040 | 1 | Twentieth Century Fox | true | false |
| 3 | - | The Bucket List | $16,664,347 | - | 2,915 | - | $5,716 | $44,223,780 | 4 | Warner Bros. | false | false |
| 4 | - | Juno | $11,966,082 | - | 2,534 | - | $4,722 | $87,092,615 | 7 | - | false | false |
| 5 | - | National Treasure: Book of Secrets | $9,606,326 | - | 2,963 | - | $3,242 | $199,489,171 | 5 | Walt Disney Studios Motion Pictures | false | false |
| 6 | - | First Sunday | $9,504,908 | - | 2,213 | - | $4,295 | $30,170,510 | 2 | Screen Gems | false | false |
| 7 | - | Alvin and the Chipmunks | $9,433,049 | - | 2,962 | - | $3,184 | $198,813,230 | 6 | Twentieth Century Fox | false | false |
| 8 | - | Mad Money | $9,273,645 | - | 2,470 | - | $3,754 | $9,273,645 | 1 | Overture Films | true | false |
| 9 | - | I Am Legend | $5,905,443 | - | 2,525 | - | $2,338 | $248,482,867 | 6 | Warner Bros. | false | false |
| 10 | - | Atonement | $5,528,377 | - | 1,291 | - | $4,282 | $32,653,183 | 7 | Focus Features | false | false |
| 11 | - | The Pirates Who Don't Do Anything | $3,805,510 | - | 1,340 | - | $2,839 | $8,692,420 | 2 | Universal Pictures | false | false |
| 12 | - | There Will Be Blood | $3,661,992 | - | 389 | - | $9,413 | $8,696,622 | 4 | Paramount Vantage | false | false |
| 13 | - | One Missed Call | $3,339,660 | - | 1,925 | - | $1,734 | $24,940,422 | 3 | Warner Bros. | false | false |
| 14 | - | Sweeney Todd: The Demon Barber of Fleet Street | $3,247,729 | - | 1,507 | - | $2,155 | $48,672,529 | 5 | DreamWorks | false | false |
| 15 | - | The Water Horse | $2,735,551 | - | 1,661 | - | $1,646 | $38,587,029 | 4 | Revolution Studios | false | false |
| 16 | - | P.S. I Love You | $2,359,694 | - | 1,626 | - | $1,451 | $50,850,355 | 5 | Warner Bros. | false | false |
| 17 | - | Charlie Wilson's War | $2,359,225 | - | 1,352 | - | $1,744 | $63,206,735 | 5 | Universal Pictures | false | false |
| 18 | - | The Great Debaters | $1,769,290 | - | 1,021 | - | $1,732 | $28,208,755 | 4 | - | false | false |
| 19 | - | No Country for Old Men | $1,521,020 | - | 818 | - | $1,859 | $48,899,543 | 11 | Miramax | false | false |
| 20 | - | Enchanted | $1,497,616 | - | 767 | - | $1,952 | $124,292,358 | 9 | Walt Disney Studios Motion Pictures | false | false |
| 21 | - | The Orphanage | $1,432,264 | - | 702 | - | $2,040 | $5,262,982 | 4 | Picturehouse | false | false |
| 22 | - | The Kite Runner | $1,333,219 | - | 606 | - | $2,200 | $12,943,619 | 6 | Paramount Vantage | false | false |
| 23 | - | In the Name of the King: A Dungeon Siege Tale | $956,697 | - | 1,338 | - | $715 | $4,535,117 | 2 | Freestyle Releasing | false | false |
| 24 | - | The Golden Compass | $607,352 | - | 340 | - | $1,786 | $68,425,138 | 7 | New Line Cinema | false | false |
| 25 | - | The Savages | $529,147 | - | 175 | - | $3,023 | $3,646,200 | 8 | - | false | false |
| 26 | - | The Diving Bell and the Butterfly | $470,789 | - | 107 | - | $4,399 | $2,611,955 | 8 | Miramax | false | false |
| 27 | - | Cassandra's Dream | $437,643 | - | 107 | - | $4,090 | $437,643 | 1 | The Weinstein Company | true | false |
| 28 | - | Aliens vs. Predator: Requiem | $396,741 | - | 410 | - | $967 | $41,288,750 | 4 | Twentieth Century Fox | false | false |
| 29 | - | Bee Movie | $331,262 | - | 296 | - | $1,119 | $125,993,358 | 12 | DreamWorks | false | false |
| 30 | - | Persepolis | $284,769 | - | 30 | - | $9,492 | $913,007 | 4 | Sony Pictures Classics | false | false |
| 31 | - | The Game Plan | $272,281 | - | 195 | - | $1,396 | $90,043,270 | 17 | Walt Disney Studios Motion Pictures | false | false |
| 32 | - | August Rush | $258,828 | - | 314 | - | $824 | $30,943,012 | 9 | Warner Bros. | false | false |
| 33 | - | Beowulf | $220,990 | - | 251 | - | $880 | $82,014,712 | 10 | Paramount Pictures | false | false |
| 34 | - | Into the Wild | $207,235 | - | 195 | - | $1,062 | $17,690,434 | 18 | Paramount Vantage | false | false |
| 35 | - | Sea Monsters: A Prehistoric Adventure | $159,322 | - | 61 | - | $2,611 | $6,815,485 | 16 | National Geographic Entertainment | false | false |
| 36 | - | Mr. Magorium's Wonder Emporium | $149,107 | - | 188 | - | $793 | $31,726,879 | 10 | Twentieth Century Fox | false | false |
| 37 | - | American Gangster | $145,815 | - | 213 | - | $684 | $129,989,615 | 12 | Universal Pictures | false | false |
| 38 | - | Dan in Real Life | $84,723 | - | 157 | - | $539 | $47,484,222 | 13 | Walt Disney Studios Motion Pictures | false | false |
| 39 | - | I'm Not There | $67,821 | - | 61 | - | $1,111 | $3,542,890 | 9 | The Weinstein Company | false | false |
| 40 | - | Before the Devil Knows You're Dead | $58,783 | - | 58 | - | $1,013 | $6,909,546 | 13 | THINKFilm | false | false |
| 41 | - | Michael Clayton | $55,867 | - | 33 | - | $1,692 | $39,399,327 | 16 | Warner Bros. | false | false |
| 42 | - | Deep Sea | $50,553 | - | 12 | - | $4,212 | $33,938,863 | 99 | Warner Bros. | false | false |
| 43 | - | Fred Claus | $50,225 | - | 88 | - | $570 | $71,868,717 | 11 | Warner Bros. | false | false |
| 44 | - | Hitman | $47,708 | - | 84 | - | $567 | $39,572,369 | 9 | Twentieth Century Fox | false | false |
| 45 | - | Little Chenier | $44,370 | - | 17 | - | $2,610 | $44,370 | 1 | Slowhand Cinema Releasing | true | false |
| 46 | - | Space Station 3D | $44,199 | - | 11 | - | $4,018 | $73,164,708 | 301 | IMAX | false | false |
| 47 | - | Magnificent Desolation: Walking on the Moon | $42,457 | - | 8 | - | $5,307 | $22,510,253 | 122 | IMAX | false | false |
| 48 | - | Teeth | $36,530 | - | 4 | - | $9,132 | $36,530 | 1 | Roadside Attractions | true | false |
| 49 | - | Days of Darkness | $36,051 | - | 23 | - | $1,567 | $1,398,163 | - | Alliance Atlantis Vivafilm | - | false |
| 50 | - | Like Stars on Earth | $32,382 | - | 20 | - | $1,619 | $1,204,660 | 5 | UTV Motion Pictures | false | false |
| 51 | - | Lions for Lambs | $31,563 | - | 95 | - | $332 | $14,971,658 | 11 | United Artists | false | false |
| 52 | - | Blonde and Blonder | $26,815 | - | 14 | - | $1,915 | $26,815 | 1 | Hannover House | true | false |
| 53 | - | Steep | $25,910 | - | 14 | - | $1,850 | $120,732 | 5 | Sony Pictures Classics | false | false |
| 54 | - | Starting Out in the Evening | $25,379 | - | 10 | - | $2,537 | $605,817 | 9 | Roadside Attractions | false | false |
| 55 | - | Lars and the Real Girl | $25,245 | - | 35 | - | $721 | $5,840,969 | 15 | Metro-Goldwyn-Mayer (MGM) | false | false |
| 56 | - | Honeydripper | $22,856 | - | 26 | - | $879 | $54,992 | 4 | Emerging Pictures | false | false |
| 57 | - | Nanking | $21,867 | - | 4 | - | $5,466 | $78,426 | 6 | THINKFilm | false | false |
| 58 | - | The Darjeeling Limited | $20,136 | - | 27 | - | $745 | $11,812,727 | 17 | - | false | false |
| 59 | - | The Mist | $19,363 | - | 33 | - | $586 | $25,392,644 | 9 | - | false | false |
| 60 | - | Last Year at Marienbad | $19,101 | - | 1 | - | $19,101 | $19,101 | 1 | Rialto Pictures | true | false |
| 61 | - | Roving Mars | $18,771 | - | 6 | - | $3,128 | $8,156,566 | 104 | Walt Disney Studios Motion Pictures | false | false |
| 62 | - | Blade Runner The Final Cut (2007 re-release) | $18,734 | - | 7 | - | $2,676 | $1,286,946 | 16 | Warner Bros. | false | false |
| 63 | - | The Business of Being Born | $18,075 | - | 3 | - | $6,025 | $42,411 | 2 | International Film Circuit | false | false |
| 64 | - | Still Life | $16,036 | - | 1 | - | $16,036 | $16,036 | 1 | New Yorker Films | true | false |
| 65 | - | Galapagos | $14,564 | - | 3 | - | $4,854 | $16,996,731 | 430 | IMAX | false | false |
| 66 | - | Awake | $14,532 | - | 23 | - | $631 | $14,209,111 | 8 | - | false | false |
| 67 | - | The Perfect Holiday | $14,402 | - | 30 | - | $480 | $5,769,813 | 6 | Yari Film Group Releasing | false | false |
| 68 | - | Day Zero | $13,800 | - | 2 | - | $6,900 | $13,800 | 1 | First Look International | true | false |
| 69 | - | Taxi to the Dark Side | $13,656 | - | 2 | - | $6,828 | $13,656 | 1 | THINKFilm | true | false |
| 70 | - | Summer Palace | $10,649 | - | 1 | - | $10,649 | $10,649 | 1 | Palm Pictures | true | false |
| 71 | - | Lust, Caution | $9,859 | - | 8 | - | $1,232 | $4,602,512 | 17 | Focus Features | false | false |
| 72 | - | Beaufort | $9,267 | - | 2 | - | $4,633 | $9,267 | 1 | Kino International | true | false |
| 73 | - | Bella | $9,223 | - | 25 | - | $368 | $7,674,562 | 13 | Roadside Attractions | false | false |
| 74 | - | Margot at the Wedding | $6,731 | - | 28 | - | $240 | $1,951,779 | 10 | Paramount Vantage | false | false |
| 75 | - | Jimmy Carter Man from Plains | $6,460 | - | 10 | - | $646 | $95,663 | 13 | Sony Pictures Classics | false | false |
| 76 | - | Youth Without Youth | $5,961 | - | 7 | - | $851 | $196,109 | 6 | Sony Pictures Classics | false | false |
| 77 | - | Romance & Cigarettes | $5,517 | - | 3 | - | $1,839 | $556,519 | 20 | - | false | false |
| 78 | - | Control | $5,364 | - | 9 | - | $596 | $867,811 | 15 | The Weinstein Company | false | false |
| 79 | - | Woman on the Beach 2008 Re-release | $5,218 | - | 1 | - | $5,218 | $12,858 | 2 | New Yorker Films | false | false |
| 80 | - | The Walker | $4,442 | - | 3 | - | $1,480 | $66,172 | 7 | THINKFilm | false | false |
| 81 | - | For the Bible Tells Me So | $4,163 | - | 3 | - | $1,387 | $281,355 | 16 | First Run | false | false |
| 82 | - | Passage to Zarahemla | $3,022 | - | 1 | - | $3,022 | $246,298 | 15 | - | false | false |
| 83 | - | My Kid Could Paint That | $2,448 | - | 4 | - | $612 | $229,241 | 16 | Sony Pictures Classics | false | false |
| 84 | - | Yiddish Theater: A Love Story | $2,234 | - | 3 | - | $744 | $24,123 | - | New Love Films | - | false |
| 85 | - | How to Cook Your Life | $2,082 | - | 2 | - | $1,041 | $68,590 | 13 | Roadside Attractions | false | false |
| 86 | - | The Assassination of Jesse James by the Coward Robert Ford | $1,883 | - | 4 | - | $470 | $3,897,011 | 18 | Warner Bros. | false | false |
| 87 | - | Imaginary Witness: Hollywood and the Holocaust | $1,286 | - | 2 | - | $643 | $8,659 | 7 | Shadow Distribution | false | false |
| 88 | - | Diva | $1,035 | - | 1 | - | $1,035 | $72,557 | 12 | Rialto Pictures | false | false |
| 89 | - | Joe Strummer: The Future Is Unwritten | $845 | - | 3 | - | $281 | $246,998 | 12 | IFC Films | false | false |
| 90 | - | Outsourced | $816 | - | 1 | - | $816 | $163,561 | - | Truly Indie | - | false |
| 91 | - | El Topo | $456 | - | 1 | - | $456 | $77,163 | 58 | ABKCO Films | false | false |
| 92 | - | The Killing of John Lennon | $414 | - | 1 | - | $414 | $6,672 | 3 | IFC Films | false | false |
| 93 | - | A Bloody Aria 2008 Re-release | $269 | - | 1 | - | $269 | $518 | - | ImaginAsian Pictures | - | false |
| 94 | - | Sleuth | $233 | - | 1 | - | $233 | $342,835 | 15 | Sony Pictures Classics | false | false |
| 95 | - | Looking for Cheyenne | $147 | - | 1 | - | $147 | $788 | 7 | Regent Releasing | false | false |
