| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | National Treasure: Book of Secrets | $359,099 | - | 23 | - | $15,613 | $621,861 | 1 | N/A | true | false |
| 2 | - | 30 Days of Night | $203,119 | - | 19 | - | $10,690 | $346,276 | 1 | N/A | true | false |
| 3 | 2 | Bee Movie | $147,058 | -41.2% | 18 | -2 | $8,169 | $574,333 | 2 | N/A | false | false |
| 4 | - | Alvin and the Chipmunks | $115,127 | - | 19 | - | $6,059 | $196,416 | 1 | N/A | true | false |
| 5 | 1 | Hitman | $105,584 | -68.4% | 19 | -1 | $5,557 | $590,181 | 2 | N/A | false | false |
| 6 | - | Fred Claus | $86,004 | - | 14 | - | $6,143 | $146,133 | 1 | N/A | true | false |
| 7 | - | Mr. Magorium's Wonder Emporium | $57,231 | - | 19 | - | $3,012 | $94,389 | 1 | N/A | true | false |
| 8 | 3 | Michael Clayton | $25,063 | -65.7% | 6 | -13 | $4,177 | $148,707 | 2 | N/A | false | false |
| 9 | 10 | Beowulf | $13,458 | -18% | 1 | -1 | $13,458 | $607,097 | 5 | N/A | false | false |
| 10 | - | Across the Universe | $12,442 | - | 6 | - | $2,073 | $12,442 | 1 | N/A | true | false |
| 11 | 4 | Blind Dating | $6,744 | -86.9% | 6 | -4 | $1,124 | $85,849 | 2 | N/A | false | false |
| 12 | 7 | Elizabeth: The Golden Age | $5,852 | -81.4% | 2 | -14 | $2,926 | $212,786 | 3 | N/A | false | false |
| 13 | 6 | The Nanny Diaries | $3,478 | -90.6% | 1 | -8 | $3,478 | $60,265 | 2 | N/A | false | false |
| 14 | 8 | The Game Plan | $3,042 | -90.1% | 1 | -8 | $3,042 | $358,854 | 4 | N/A | false | false |
| 15 | 5 | The Invisible | $2,894 | -93.3% | 2 | -16 | $1,447 | $206,866 | 3 | N/A | false | false |
| 16 | 14 | The Kingdom | $2,837 | +81.3% | 1 | - | $2,837 | $1,184,419 | 11 | N/A | false | false |
| 17 | 18 | Justified Betrayal | $1,941 | +75.8% | 1 | - | $1,941 | $132,510 | 5 | N/A | false | false |
| 18 | 12 | Delta Farce | $853 | -65.6% | 1 | - | $853 | $90,178 | 4 | N/A | false | false |
| 19 | 13 | In the Land of Women | $708 | -66.6% | 1 | - | $708 | $42,873 | 3 | N/A | false | false |
| 20 | 16 | The Last Mimzy | $300 | -75% | 1 | - | $300 | $25,208 | 3 | N/A | false | false |
