| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Enchanted | $35,332,000 | $34,440,317 | -$891,683 | -2.5% | 3,730 | $50,048,000 | $49,060,281 | 1 | Walt Disney Studios Motion Pictures | - |
| 2 | 2 | - | This Christmas | $18,600,000 | $17,958,183 | -$641,817 | -3.5% | 1,858 | $27,100,000 | $26,341,492 | 1 | Screen Gems | - |
| 3 | 3 | - | Beowulf | $16,240,000 | $16,538,666 | +$298,666 | +1.8% | 3,218 | $56,361,000 | $56,633,821 | 2 | Paramount Pictures | - |
| 4 | 4 | - | Hitman | $13,035,000 | $13,180,769 | +$145,769 | +1.1% | 2,458 | $21,000,000 | $21,094,148 | 1 | Twentieth Century Fox | - |
| 5 | 5 | - | Bee Movie | $12,010,000 | $11,813,502 | -$196,498 | -1.6% | 3,507 | $112,069,000 | $111,860,810 | 4 | DreamWorks | - |
| 6 | 6 | - | Fred Claus | $10,735,000 | $10,575,400 | -$159,600 | -1.5% | 3,603 | $53,070,000 | $52,869,835 | 3 | Warner Bros. | - |
| 7 | 7 | - | August Rush | $9,430,000 | $9,421,369 | -$8,631 | <0.1% | 2,310 | $13,330,000 | $13,243,069 | 1 | Warner Bros. | - |
| 8 | 8 | - | American Gangster | $9,207,000 | $9,013,925 | -$193,075 | -2.1% | 2,799 | $115,774,000 | $115,550,290 | 4 | Universal Pictures | - |
| 9 | 9 | - | The Mist | $9,062,000 | $8,931,973 | -$130,027 | -1.4% | 2,423 | $13,012,000 | $12,861,800 | 1 | Metro-Goldwyn-Mayer (MGM) | - |
| 10 | 10 | - | No Country for Old Men | $8,112,000 | - | - | - | 860 | $16,640,000 | - | 3 | Miramax | - |
| 11 | 11 | - | Mr. Magorium's Wonder Emporium | $8,000,000 | $7,936,035 | -$63,965 | -0.8% | 3,168 | $22,287,000 | $22,179,439 | 2 | Twentieth Century Fox | - |
| 12 | 12 | - | Dan in Real Life | $3,261,000 | $3,016,800 | -$244,200 | -7.5% | 1,502 | $42,448,000 | $42,177,151 | 5 | Walt Disney Studios Motion Pictures | - |
| 13 | 13 | - | Lions for Lambs | $1,157,000 | $1,163,124 | +$6,124 | +0.5% | 1,527 | $13,792,000 | $13,795,571 | 3 | United Artists | - |
| 14 | 14 | - | Before the Devil Knows You're Dead | $981,000 | - | - | - | 260 | $3,533,000 | - | 5 | THINKFilm | - |
| 15 | 15 | - | Love in the Time of Cholera | $910,000 | - | - | - | 852 | $3,457,000 | - | 2 | New Line Cinema | - |
| 16 | 16 | - | Bella | $792,000 | $739,628 | -$52,372 | -6.6% | 357 | $6,255,000 | $6,193,126 | 5 | Roadside Attractions | - |
| 17 | 17 | - | I'm Not There | $757,000 | $730,819 | -$26,181 | -3.5% | 130 | $1,001,000 | $974,601 | 1 | The Weinstein Company | - |
| 18 | 18 | - | Into the Wild | $721,000 | $708,069 | -$12,931 | -1.8% | 354 | $15,025,000 | $15,001,671 | 10 | Paramount Vantage | - |
| 19 | 19 | - | Michael Clayton | $600,000 | $536,049 | -$63,951 | -10.7% | 301 | $38,111,000 | $38,042,902 | 8 | Warner Bros. | - |
| 20 | 20 | - | Saw IV | $460,000 | $426,189 | -$33,811 | -7.4% | 531 | $62,885,000 | $62,850,782 | 5 | Lionsgate | - |
| 21 | 21 | - | Gone Baby Gone | $414,000 | - | - | - | 251 | $19,098,000 | - | 6 | Miramax | - |
| 22 | 22 | - | Margot at the Wedding | $382,000 | $376,837 | -$5,163 | -1.4% | 35 | $574,000 | $565,352 | 2 | Paramount Vantage | - |
| 23 | 25 | +2 | The Game Plan | $351,000 | $353,011 | +$2,011 | +0.6% | 425 | $88,146,000 | $88,146,125 | 9 | Walt Disney Studios Motion Pictures | - |
| 24 | 26 | +2 | Why Did I Get Married? | $350,000 | $305,603 | -$44,397 | -12.7% | 221 | $54,944,000 | $54,900,951 | 7 | Lionsgate | - |
| 25 | 32 | +7 | The Bourne Ultimatum | $135,000 | $137,065 | +$2,065 | +1.5% | 184 | $227,435,000 | $227,437,090 | 17 | Universal Pictures | - |
| 26 | 34 | +8 | Lust, Caution | $100,000 | $96,128 | -$3,872 | -3.9% | 49 | $4,214,000 | $4,209,806 | 9 | Focus Features | - |
| 27 | 37 | +10 | Starting Out in the Evening | $85,600 | $76,214 | -$9,386 | -11% | 7 | $85,600 | $76,214 | 1 | Roadside Attractions | - |
| 28 | 42 | +14 | P2 | $71,000 | $61,605 | -$9,395 | -13.2% | 125 | $3,902,000 | $3,891,556 | 3 | Summit Entertainment | - |
| 29 | 40 | +11 | Elizabeth: The Golden Age | $67,000 | $69,685 | +$2,685 | +4% | 77 | $16,261,000 | $16,264,475 | 7 | Universal Pictures | - |
| 30 | 51 | +21 | Control | $32,000 | $31,973 | -$27 | <0.1% | 26 | $691,000 | $694,717 | 7 | The Weinstein Company | - |
| 31 | 50 | +19 | The Kingdom | $31,000 | $33,875 | +$2,875 | +9.3% | 76 | $47,454,000 | $47,456,450 | 9 | Universal Pictures | - |
| 32 | 62 | +30 | Holly | $16,000 | $16,554 | +$554 | +3.5% | 9 | $73,000 | $76,662 | 3 | Priority Films | - |
| 33 | 63 | +30 | Pete Seeger: The Power of Song | $12,900 | $14,157 | +$1,257 | +9.7% | 2 | $83,400 | $84,443 | 5 | The Weinstein Company | - |
| 34 | 95 | +61 | The List | $2,100 | $1,727 | -$373 | -17.8% | 2 | $128,000 | $127,542 | 16 | Mountain Top Releasing | - |
| 35 | 110 | +75 | Smiley Face | $735 | $628 | -$107 | -14.6% | 1 | $8,900 | $8,768 | 2 | First Look International | - |
