| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ratatouille | $818,642 | -9.5% | 97 | - | $8,439 | $4,731,289 | 11 | Walt Disney Pictures | false | false |
| 2 | 2 | The Bourne Ultimatum | $126,119 | -41.5% | 40 | -14 | $3,152 | $2,797,151 | 6 | Universal Pictures International (UPI) | false | false |
| 3 | 6 | Surf's Up | $111,533 | -6.3% | 60 | - | $1,858 | $594,470 | 5 | Walt Disney Pictures | false | false |
| 4 | - | Disturbia | $96,774 | - | 23 | - | $4,207 | $298,936 | 8 | Universal Pictures International (UPI) | false | false |
| 5 | 7 | Death at a Funeral | $79,913 | -21.6% | 24 | +2 | $3,329 | $1,184,088 | 7 | Ascot Elite Entertainment Group | false | false |
| 6 | 3 | Tell | $72,104 | -47.7% | 37 | -15 | $1,948 | $584,144 | 3 | Universal Pictures International (UPI) | false | false |
| 7 | 4 | Superbad | $67,665 | -48.2% | 32 | -2 | $2,114 | $253,341 | 4 | Walt Disney Pictures | false | false |
| 8 | 5 | The Brave One | $61,674 | -51% | 34 | -13 | $1,813 | $470,718 | 3 | Warner Bros. | false | false |
| 9 | - | Becoming Jane | $57,808 | - | 12 | - | $4,817 | $59,063 | 1 | Ascot Elite Entertainment Group | true | false |
| 10 | - | Persepolis | $57,512 | - | 14 | - | $4,108 | $392,423 | 8 | Filmcoopi Zürich | false | false |
| 11 | 10 | 99 Francs | $51,086 | -17.6% | 12 | +1 | $4,257 | $243,078 | 3 | Pathé | false | false |
| 12 | 15 | Stardust | $49,821 | +72.6% | 17 | - | $2,930 | $167,979 | 3 | Universal Pictures International (UPI) | false | false |
| 13 | - | Earth | $43,557 | - | 13 | - | $3,350 | $139,336 | 1 | Frenetic Films | true | false |
| 14 | 20 | Knocked Up | $41,774 | +110.9% | 19 | +11 | $2,198 | $1,008,474 | 8 | Universal Pictures International (UPI) | false | false |
| 15 | - | Sicko | $41,315 | - | 13 | - | $3,178 | $180,667 | 6 | Ascot Elite Entertainment Group | false | false |
| 16 | 8 | No Reservations | $40,452 | -37.4% | 19 | -8 | $2,129 | $742,107 | 5 | Warner Bros. | false | false |
| 17 | 11 | The Edge of Heaven | $39,880 | -23.4% | 13 | - | $3,067 | $100,586 | 2 | Cineworx | false | false |
| 18 | 9 | 1408 | $39,119 | -39.1% | 17 | +1 | $2,301 | $396,656 | 4 | Ascot Elite Entertainment Group | false | false |
| 19 | - | The Assassination of Jesse James by the Coward Robert Ford | $36,244 | - | 7 | - | $5,177 | $40,530 | 1 | Warner Bros. | true | false |
| 20 | 13 | A Secret | $27,222 | -10.8% | 4 | - | $6,805 | $76,814 | 2 | JMH Distribution | false | false |
