| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | The Game Plan | $22,675,000 | $22,950,971 | +$275,971 | +1.2% | 3,103 | $22,675,000 | $22,950,971 | 1 | Walt Disney Studios Motion Pictures | - |
| 2 | 2 | - | The Kingdom | $17,694,000 | $17,135,055 | -$558,945 | -3.2% | 2,793 | $17,694,000 | $17,135,055 | 1 | Universal Pictures | - |
| 3 | 3 | - | Resident Evil: Extinction | $8,000,000 | $8,036,405 | +$36,405 | +0.5% | 2,828 | $36,790,000 | $36,826,411 | 2 | Screen Gems | - |
| 4 | 4 | - | Good Luck Chuck | $6,300,000 | $6,244,066 | -$55,934 | -0.9% | 2,612 | $23,569,000 | $23,513,142 | 2 | Lionsgate | - |
| 5 | 5 | - | 3:10 to Yuma | $4,160,000 | $4,208,366 | +$48,366 | +1.2% | 3,006 | $43,904,000 | $43,951,910 | 4 | Lionsgate | - |
| 6 | 6 | - | The Brave One | $3,760,000 | $3,719,285 | -$40,715 | -1.1% | 2,837 | $30,875,000 | $30,834,753 | 3 | Warner Bros. | - |
| 7 | 7 | - | Mr. Woodcock | $3,000,000 | - | - | - | 2,195 | $19,631,000 | - | 3 | New Line Cinema | - |
| 8 | 8 | - | Eastern Promises | $2,892,000 | $2,938,847 | +$46,847 | +1.6% | 1,408 | $11,234,000 | $11,281,492 | 3 | Focus Features | - |
| 9 | 9 | - | Sydney White | $2,685,000 | $2,569,515 | -$115,485 | -4.3% | 2,106 | $8,565,000 | $8,449,395 | 2 | Universal Pictures | - |
| 10 | 10 | - | Across the Universe | $2,050,000 | $2,016,224 | -$33,776 | -1.6% | 339 | $5,510,000 | $5,476,433 | 3 | Revolution Studios | - |
| 11 | 12 | +1 | Feast of Love | $1,754,000 | $1,707,967 | -$46,033 | -2.6% | 1,200 | $1,754,000 | $1,707,967 | 1 | Metro-Goldwyn-Mayer (MGM) | - |
| 12 | 11 | -1 | The Bourne Ultimatum | $1,746,000 | $1,745,475 | -$525 | <0.1% | 1,461 | $222,789,000 | $222,788,180 | 9 | Universal Pictures | - |
| 13 | 13 | - | Superbad | $1,650,000 | $1,633,952 | -$16,048 | -1% | 1,517 | $118,874,000 | $118,858,438 | 7 | Sony Pictures Releasing | - |
| 14 | 14 | - | In the Valley of Elah | $1,530,000 | $1,512,310 | -$17,690 | -1.2% | 762 | $3,460,000 | $3,438,958 | 3 | Warner Independent Pictures (WIP) | - |
| 15 | 15 | - | Transformers | $1,202,000 | $1,200,730 | -$1,270 | -0.1% | 509 | $315,176,000 | $315,175,018 | 13 | DreamWorks | - |
| 16 | 16 | - | Rush Hour 3 | $1,145,000 | - | - | - | 1,152 | $137,654,000 | - | 8 | New Line Cinema | - |
| 17 | 17 | - | Dragon Wars: D-War | $1,057,000 | - | - | - | 1,376 | $10,163,000 | - | 3 | Freestyle Releasing | - |
| 18 | 18 | - | Halloween | $905,000 | $990,099 | +$85,099 | +9.4% | 1,245 | $56,116,000 | $56,201,164 | 5 | Metro-Goldwyn-Mayer (MGM) | - |
| 19 | 19 | - | Mr. Bean's Holiday | $675,000 | $719,325 | +$44,325 | +6.6% | 1,262 | $31,775,000 | $31,818,685 | 6 | Universal Pictures | - |
| 20 | 20 | - | Into the Wild | $669,000 | $631,451 | -$37,549 | -5.6% | 33 | $968,000 | $930,015 | 2 | Paramount Vantage | - |
| 21 | 21 | - | Balls of Fury | $550,000 | $560,486 | +$10,486 | +1.9% | 867 | $32,131,000 | $32,141,543 | 5 | Rogue Pictures | - |
| 22 | 22 | - | Hairspray | $375,000 | - | - | - | 496 | $118,003,000 | - | 11 | New Line Cinema | - |
| 23 | 25 | +2 | Stardust | $267,000 | $259,349 | -$7,651 | -2.9% | 341 | $37,820,000 | $37,812,484 | 8 | Paramount Pictures | - |
| 24 | 30 | +6 | The Jane Austen Book Club | $210,000 | - | - | - | 41 | $418,000 | - | 2 | Sony Pictures Classics | - |
| 25 | 31 | +6 | I Now Pronounce You Chuck & Larry | $209,000 | $208,955 | -$45 | <0.1% | 329 | $119,318,000 | $119,318,320 | 11 | Universal Pictures | - |
| 26 | 32 | +6 | In the Shadow of the Moon | $196,000 | $186,769 | -$9,231 | -4.7% | 98 | $580,000 | $569,814 | 4 | THINKFilm | - |
| 27 | 34 | +7 | Silk | $159,000 | $164,333 | +$5,333 | +3.4% | 83 | $687,000 | $692,136 | 3 | Picturehouse | - |
| 28 | 37 | +9 | The Darjeeling Limited | $140,000 | $134,938 | -$5,062 | -3.6% | 2 | $140,000 | $134,938 | 1 | Fox Searchlight Pictures | - |
| 29 | 38 | +9 | Becoming Jane | $128,000 | $127,024 | -$976 | -0.8% | 301 | $18,497,000 | $18,495,762 | 9 | Miramax | - |
| 30 | 39 | +9 | Trade | $114,000 | $118,086 | +$4,086 | +3.6% | 90 | $114,000 | $118,086 | 1 | Roadside Attractions | - |
| 31 | 42 | +11 | The Assassination of Jesse James by the Coward Robert Ford | $92,000 | $92,351 | +$351 | +0.4% | 5 | $301,000 | $300,737 | 2 | Warner Bros. | - |
| 32 | 47 | +15 | Evan Almighty | $73,000 | $71,320 | -$1,680 | -2.3% | 147 | $100,291,000 | $100,289,690 | 15 | Universal Pictures | - |
| 33 | 44 | +11 | Ladrón que roba a ladrón | $72,000 | $74,407 | +$2,407 | +3.3% | 101 | $3,893,000 | $3,895,601 | 5 | Lionsgate | - |
| 34 | 49 | +15 | Lust, Caution | $61,700 | $63,918 | +$2,218 | +3.6% | 1 | $61,700 | $63,918 | 1 | Focus Features | - |
| 35 | 54 | +19 | Bratz | $54,000 | $40,020 | -$13,980 | -25.9% | 73 | $9,806,000 | $9,792,329 | 9 | Lionsgate | - |
| 36 | 52 | +16 | King of California | $44,400 | $42,392 | -$2,008 | -4.5% | 28 | $141,000 | $139,452 | 3 | First Look International | - |
| 37 | 51 | +14 | War | $43,000 | $42,421 | -$579 | -1.3% | 104 | $22,468,000 | $22,466,994 | 6 | Lionsgate | - |
| 38 | 56 | +18 | Sicko | $39,000 | $32,742 | -$6,258 | -16% | 89 | $24,488,000 | $24,481,743 | 15 | Lionsgate | - |
| 39 | 55 | +16 | Sharkwater | $35,400 | $37,140 | +$1,740 | +4.9% | 60 | $792,000 | $793,384 | 1 | Freestyle Releasing | - |
| 40 | 79 | +39 | The List | $10,400 | $9,524 | -$876 | -8.4% | 2 | $93,300 | $92,466 | 8 | Mountain Top Releasing | - |
| 41 | 84 | +43 | Manda Bala (Send a Bullet) | $8,400 | $7,361 | -$1,039 | -12.4% | 9 | $99,400 | $98,381 | 7 | City Lights Pictures | - |
| 42 | 80 | +38 | Chalk | $7,900 | $9,133 | +$1,233 | +15.6% | 3 | $299,000 | $300,633 | 21 | Hart Sharp Entertainment | - |
