| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Bourne Ultimatum | $365,401 | -35.1% | 80 | -4 | $4,567 | $1,925,483 | 3 | Universal Pictures International (UPI) | false | false |
| 2 | 2 | No Reservations | $137,826 | -24.1% | 49 | -1 | $2,812 | $411,963 | 2 | Warner Bros. | false | false |
| 3 | - | 1408 | $121,415 | - | 20 | - | $6,070 | $121,415 | 1 | Ascot Elite Entertainment Group | true | false |
| 4 | 3 | Death at a Funeral | $120,816 | +17.7% | 30 | +8 | $4,027 | $757,214 | 4 | Ascot Elite Entertainment Group | false | false |
| 5 | - | Shoot 'Em Up | $67,442 | - | 35 | - | $1,926 | $70,084 | 1 | Warner Bros. | true | false |
| 6 | 9 | A Mighty Heart | $62,924 | +12.7% | 28 | +8 | $2,247 | $143,954 | 2 | Universal Pictures International (UPI) | false | false |
| 7 | - | Hot Fuzz | $57,242 | - | 21 | - | $2,725 | $84,776 | 1 | Universal Pictures International (UPI) | true | false |
| 8 | 4 | Knocked Up | $52,639 | -37.2% | 26 | -3 | $2,024 | $871,208 | 5 | Universal Pictures International (UPI) | false | false |
| 9 | 10 | Ratatouille | $51,698 | +4.4% | 19 | -3 | $2,720 | $2,385,205 | 8 | Walt Disney Pictures | false | false |
| 10 | 7 | Surf's Up | $49,650 | -28.6% | 41 | - | $1,210 | $148,227 | 2 | Walt Disney Pictures | false | false |
| 11 | 8 | The Simpsons Movie | $43,928 | -35.6% | 26 | -15 | $1,689 | $5,440,061 | 9 | 20th Century Fox International | false | false |
| 12 | 5 | Rush Hour 3 | $37,811 | -51% | 18 | -12 | $2,100 | $1,364,500 | 6 | Warner Bros. | false | false |
| 13 | 6 | Hairspray | $34,434 | -51.2% | 24 | -15 | $1,434 | $450,229 | 5 | Warner Bros. | false | false |
| 14 | - | 28 Weeks Later | $33,185 | - | 8 | - | $4,148 | $148,265 | 4 | 20th Century Fox International | false | false |
| 15 | - | Dutti der Riese | $31,893 | - | 24 | - | $1,328 | $36,101 | 1 | Frenetic Films | true | false |
| 16 | 11 | Hunting and Gathering | $27,857 | -11.8% | 11 | - | $2,532 | $909,037 | 27 | Pathé | false | false |
| 17 | 13 | Persepolis | $22,179 | -8.3% | 12 | -1 | $1,848 | $265,131 | 5 | Filmcoopi | false | false |
| 18 | - | L'invité | $18,345 | - | 4 | - | $4,586 | $20,488 | 1 | Pathé | true | false |
| 19 | 12 | Shrek the Third | $18,082 | -38.2% | 10 | -1 | $1,808 | $5,281,600 | 14 | Universal Pictures International (UPI) | false | false |
| 20 | - | A Girl Cut in Two | $18,034 | - | 8 | - | $2,254 | $20,672 | 1 | JMH Distribution | true | false |
