| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Bourne Ultimatum | $562,595 | +5.7% | 84 | +27 | $6,697 | $1,378,578 | 2 | Universal Pictures International (UPI) | false | false |
| 2 | - | No Reservations | $181,657 | - | 50 | - | $3,633 | $205,594 | 1 | Warner Bros. | true | false |
| 3 | 2 | Death at a Funeral | $102,677 | -30.8% | 22 | - | $4,667 | $586,055 | 3 | Ascot Elite Entertainment Group | false | false |
| 4 | 3 | Knocked Up | $83,768 | -37.2% | 29 | -3 | $2,888 | $786,185 | 4 | Universal Pictures International (UPI) | false | false |
| 5 | 5 | Rush Hour 3 | $77,195 | -32.2% | 30 | -14 | $2,573 | $1,295,418 | 5 | Warner Bros. | false | false |
| 6 | 4 | Hairspray | $70,554 | -44.2% | 39 | -11 | $1,809 | $388,040 | 4 | Warner Bros. | false | false |
| 7 | - | Surf's Up | $69,527 | - | 41 | - | $1,695 | $69,527 | 1 | Walt Disney Pictures | true | false |
| 8 | 7 | The Simpsons Movie | $68,165 | -8.1% | 41 | -8 | $1,662 | $5,296,402 | 8 | 20th Century Fox International | false | false |
| 9 | - | A Mighty Heart | $55,854 | - | 20 | - | $2,792 | $55,854 | 1 | Universal Pictures International (UPI) | true | false |
| 10 | 6 | Ratatouille | $49,506 | -50.4% | 22 | -2 | $2,250 | $2,277,643 | 7 | Walt Disney Pictures | false | false |
| 11 | 8 | Hunting and Gathering | $31,591 | -32.3% | 11 | +1 | $2,871 | $850,683 | 26 | Pathé | false | false |
| 12 | 9 | Shrek the Third | $29,243 | -34.8% | 11 | -5 | $2,658 | $5,182,946 | 13 | Universal Pictures International (UPI) | false | false |
| 13 | 13 | Persepolis | $24,182 | -31.4% | 13 | +1 | $1,860 | $225,361 | 4 | Filmcoopi | false | false |
| 14 | 10 | Sicko | $20,487 | -46.1% | 9 | - | $2,276 | $88,979 | 2 | Ascot Elite Entertainment Group | false | false |
| 15 | 12 | Harry Potter and the Order of the Phoenix | $19,491 | -46.2% | 17 | -9 | $1,146 | $6,447,583 | 10 | Warner Bros. | false | false |
| 16 | 16 | Disturbia | $18,694 | -22.1% | 13 | +2 | $1,438 | $187,190 | 4 | Universal Pictures International (UPI) | false | false |
| 17 | 11 | Because I Said So | $17,684 | -52.8% | 15 | -6 | $1,178 | $508,168 | 26 | Ascot Elite Entertainment Group | false | false |
| 18 | 14 | Evan Almighty | $16,872 | -49.7% | 17 | -8 | $992 | $402,612 | 5 | Universal Pictures International (UPI) | false | false |
| 19 | 18 | 4 Months, 3 Weeks and 2 Days | $12,918 | -36.3% | 7 | - | $1,845 | $80,604 | 3 | Frenetic Films | false | false |
| 20 | - | True Enough | $12,808 | - | 5 | - | $2,561 | $14,888 | 1 | Agora Films | true | false |
