| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Ratatouille | $47,227,000 | $47,027,395 | -$199,605 | -0.4% | 3,940 | $47,227,000 | $47,027,395 | 1 | Walt Disney Studios Motion Pictures | - |
| 2 | 2 | - | Live Free or Die Hard | $33,150,000 | $33,369,559 | +$219,559 | +0.7% | 3,408 | $48,178,000 | $48,398,130 | 1 | Twentieth Century Fox | - |
| 3 | 3 | - | Evan Almighty | $15,089,000 | $15,143,945 | +$54,945 | +0.4% | 3,636 | $60,625,000 | $60,679,545 | 2 | Universal Pictures | - |
| 4 | 4 | - | 1408 | $10,610,000 | $10,662,804 | +$52,804 | +0.5% | 2,733 | $40,389,000 | $40,442,058 | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 5 | 5 | - | Fantastic Four: Rise of the Silver Surfer | $9,000,000 | $9,143,876 | +$143,876 | +1.6% | 3,424 | $114,800,000 | $114,944,684 | 3 | Twentieth Century Fox | - |
| 6 | 6 | - | Knocked Up | $7,418,000 | $7,302,325 | -$115,675 | -1.6% | 2,665 | $122,407,000 | $122,291,755 | 5 | Universal Pictures | - |
| 7 | 7 | - | Ocean's Thirteen | $6,050,000 | $6,085,959 | +$35,959 | +0.6% | 2,903 | $102,085,000 | $102,120,537 | 4 | Warner Bros. | - |
| 8 | 8 | - | Pirates of the Caribbean: At World's End | $5,015,000 | $4,960,368 | -$54,632 | -1.1% | 2,162 | $295,758,000 | $295,703,075 | 6 | Walt Disney Studios Motion Pictures | - |
| 9 | 9 | - | Sicko | $4,500,000 | $4,501,712 | +$1,712 | <0.1% | 441 | $4,615,000 | $4,616,786 | 2 | Lionsgate | - |
| 10 | 10 | - | Evening | $3,513,000 | - | - | - | 977 | $3,513,000 | - | 1 | Focus Features | - |
| 11 | 11 | - | Shrek the Third | $2,745,000 | $2,673,877 | -$71,123 | -2.6% | 2,066 | $313,811,000 | $313,739,703 | 7 | DreamWorks | - |
| 12 | 12 | - | Surf's Up | $2,400,000 | $2,446,757 | +$46,757 | +1.9% | 2,503 | $53,814,000 | $53,760,658 | 4 | Sony Pictures Releasing | - |
| 13 | 13 | - | Nancy Drew | $1,945,000 | $1,876,247 | -$68,753 | -3.5% | 1,932 | $21,280,000 | $21,210,986 | 3 | Warner Bros. | - |
| 14 | 14 | - | A Mighty Heart | $1,558,000 | $1,587,323 | +$29,323 | +1.9% | 1,350 | $6,976,000 | $7,005,463 | 2 | Paramount Vantage | - |
| 15 | 15 | - | La Vie En Rose | $612,000 | $617,080 | +$5,080 | +0.8% | 142 | $4,929,000 | $4,933,571 | 4 | Picturehouse | - |
| 16 | 16 | - | Spider-Man 3 | $600,000 | $602,153 | +$2,153 | +0.4% | 609 | $333,691,000 | $333,693,426 | 9 | Sony Pictures Releasing | - |
| 17 | 17 | - | Waitress | $457,000 | $469,384 | +$12,384 | +2.7% | 314 | $16,759,000 | $16,761,797 | 9 | Fox Searchlight Pictures | - |
| 18 | 19 | +1 | Once | $370,000 | $381,336 | +$11,336 | +3.1% | 128 | $3,831,000 | $3,842,578 | 7 | Fox Searchlight Pictures | - |
| 19 | 21 | +2 | Paris, Je T'aime | $203,000 | - | - | - | 105 | $3,816,000 | - | 9 | First Look International | - |
| 20 | 24 | +4 | You Kill Me | $166,000 | - | - | - | 39 | $503,000 | - | 2 | IFC Films | - |
| 21 | 26 | +5 | Hostel: Part II | $134,000 | $141,359 | +$7,359 | +5.5% | 181 | $17,537,000 | $17,544,812 | 4 | Lionsgate | - |
| 22 | 30 | +8 | Hot Fuzz | $79,600 | $85,826 | +$6,226 | +7.8% | 164 | $23,329,000 | $23,335,665 | 11 | Rogue Pictures | - |
| 23 | 33 | +10 | Golden Door | $62,500 | $63,778 | +$1,278 | +2% | 30 | $482,000 | $483,188 | 6 | Miramax | - |
| 24 | 36 | +12 | Paprika | $44,500 | $44,111 | -$389 | -0.9% | 31 | $576,000 | $575,388 | 6 | Sony Pictures Classics | - |
| 25 | 37 | +12 | Black Book | $36,500 | $42,754 | +$6,254 | +17.1% | 35 | $4,237,000 | $4,243,113 | 13 | Sony Pictures Classics | - |
| 26 | 44 | +18 | The Valet | $33,700 | $24,537 | -$9,163 | -27.2% | 33 | $1,828,000 | $1,818,636 | 11 | Sony Pictures Classics | - |
| 27 | 42 | +15 | The Lives of Others | $32,500 | $29,468 | -$3,032 | -9.3% | 22 | $10,751,000 | $10,748,017 | 21 | Sony Pictures Classics | - |
| 28 | 38 | +10 | Away from Her | $31,500 | $38,287 | +$6,787 | +21.5% | 52 | $4,282,000 | $4,443,603 | 9 | Lionsgate | - |
| 29 | 48 | +19 | Eagle vs Shark | $16,150 | $16,478 | +$328 | +2% | 15 | $106,000 | $106,760 | 3 | Miramax | - |
| 30 | 49 | +19 | Gracie | $12,700 | $15,904 | +$3,204 | +25.2% | 35 | $2,920,000 | $2,922,776 | 5 | Picturehouse | - |
| 31 | 57 | +26 | Ghosts of Cité Soleil | $7,400 | $7,100 | -$300 | -4.1% | 1 | $10,000 | $9,720 | 1 | THINKFilm | - |
| 32 | 64 | +32 | Vitus | $5,300 | $5,722 | +$422 | +8% | 2 | $5,300 | $7,951 | 1 | Sony Pictures Classics | - |
