| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Pirates of the Caribbean: At World's End | $1,790,051 | - | 204 | - | $8,774 | $2,654,137 | 1 | N/A | true | false |
| 2 | 2 | 28 Weeks Later | $49,919 | -75.5% | 44 | -17 | $1,134 | $341,181 | 2 | N/A | false | false |
| 3 | 1 | Spider-Man 3 | $45,858 | -80.3% | 67 | -68 | $684 | $5,319,297 | 4 | N/A | false | false |
| 4 | 3 | Next | $36,481 | -79.3% | 53 | -11 | $688 | $721,459 | 3 | N/A | false | false |
| 5 | 5 | The Last Mimzy | $10,632 | -75.7% | 26 | -5 | $408 | $64,952 | 2 | N/A | false | false |
| 6 | 6 | Death Water | $7,257 | -82.1% | 27 | -3 | $268 | $59,710 | 2 | N/A | false | false |
| 7 | 8 | Wild Hogs | $3,867 | -86.9% | 11 | -10 | $351 | $101,717 | 3 | N/A | false | false |
| 8 | 4 | Epic Movie | $2,264 | -95.3% | 10 | -22 | $226 | $213,563 | 3 | N/A | false | false |
| 9 | 7 | Train of the Dead | $1,517 | -95.5% | 10 | -32 | $151 | $180,797 | 3 | N/A | false | false |
| 10 | 9 | Protégé | $908 | -94.9% | 8 | -22 | $113 | $77,414 | 3 | N/A | false | false |
| 11 | 10 | Now and Forever | $698 | -92.2% | 2 | -7 | $349 | $36,954 | 3 | N/A | false | false |
| 12 | - | One Missed Call 3: Final | $695 | - | 1 | - | $695 | $695 | 1 | N/A | true | false |
| 13 | 12 | Shooter | $254 | -84.6% | 1 | -3 | $254 | $622,510 | 6 | N/A | false | false |
| 14 | 14 | Pan's Labyrinth | $197 | -45.4% | 1 | - | $197 | $86,203 | 7 | N/A | false | false |
| 15 | 11 | Me... Myself | $96 | -98.3% | 2 | -7 | $48 | $1,043,070 | 6 | N/A | false | false |
