| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Pirates of the Caribbean: At World's End | $9,869,415 | - | 606 | - | $16,286 | $9,869,415 | 1 | Buena Vista International | true | false |
| 2 | 1 | Spider-Man 3 | $944,721 | -57.6% | 408 | -91 | $2,315 | $17,564,130 | 4 | Sony Pictures Releasing | false | false |
| 3 | 2 | Zodiac | $536,216 | -42.6% | 182 | - | $2,946 | $1,792,662 | 2 | Warner Bros. | false | false |
| 4 | 3 | Georgia Rule | $273,473 | -41.3% | 167 | -2 | $1,637 | $1,662,959 | 3 | Hoyts Distribution | false | false |
| 5 | 6 | Breach | $235,488 | -21.7% | 92 | +1 | $2,559 | $651,542 | 2 | Rialto Distribution | false | false |
| 6 | 5 | Because I Said So | $212,142 | -44.9% | 155 | -12 | $1,368 | $2,521,283 | 4 | Magna Pacific | false | false |
| 7 | 4 | 28 Weeks Later | $179,971 | -58.1% | 155 | -6 | $1,161 | $1,587,117 | 3 | 20th Century Fox International | false | false |
| 8 | - | Off the Grid | $84,627 | - | 2 | - | $42,313 | $84,627 | 1 | Warren Miller Entertainment | true | false |
| 9 | 10 | The History Boys | $77,317 | -41.8% | 54 | - | $1,431 | $849,457 | 4 | 20th Century Fox International | false | false |
| 10 | - | My Best Friend | $74,456 | - | 18 | - | $4,136 | $186,141 | 1 | Hopscotch Films | true | false |
| 11 | 7 | Shooter | $66,041 | -63.8% | 68 | -61 | $971 | $4,270,416 | 6 | Paramount Pictures International | false | false |
| 12 | 11 | The Lives of Others | $61,587 | -21.2% | 33 | -1 | $1,866 | $1,750,853 | 9 | Hopscotch Films | false | false |
| 13 | 12 | Noise | $59,362 | -23.3% | 17 | +3 | $3,491 | $382,085 | 4 | Madman Entertainment | false | false |
| 14 | 8 | Reno 911!: Miami | $57,668 | -66.8% | 86 | -2 | $670 | $277,522 | 2 | Paramount Pictures International | false | false |
| 15 | 13 | The Italian | $51,136 | -21.4% | 8 | -1 | $6,392 | $365,257 | 5 | Sharmill Films | false | false |
| 16 | 14 | Paris, I Love You | $49,612 | -23.1% | 28 | - | $1,771 | $967,195 | 6 | Madman Entertainment | false | false |
| 17 | 19 | As It Is in Heaven | $37,603 | -21.1% | 15 | -2 | $2,506 | $895,361 | 43 | Rialto Distribution | false | false |
| 18 | 9 | Lucky You | $35,625 | -77.5% | 88 | -56 | $404 | $673,832 | 3 | Roadshow Films | false | false |
| 19 | 16 | Wild Hogs | $27,923 | -49.6% | 39 | -20 | $715 | $14,062,601 | 12 | Buena Vista International | false | false |
| 20 | - | Shootout at Lokhandwala | $26,591 | - | 7 | - | $3,798 | $26,591 | 1 | MG Distribution | true | false |
