| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Rocky Balboa | $1,714,140 | - | 219 | - | $7,827 | $1,739,087 | 1 | 20th Century Fox International | true | false |
| 2 | - | Norbit | $1,423,122 | - | 223 | - | $6,381 | $1,423,122 | 1 | Paramount Pictures International | true | false |
| 3 | 2 | Music and Lyrics | $1,151,317 | -35.4% | 275 | - | $4,186 | $4,070,323 | 2 | Warner Bros. | false | false |
| 4 | 1 | Ghost Rider | $1,023,905 | -47.4% | 208 | - | $4,922 | $3,442,351 | 2 | Sony Pictures Releasing | false | false |
| 5 | 3 | Notes on a Scandal | $662,772 | -16.8% | 114 | +13 | $5,813 | $2,089,485 | 2 | 20th Century Fox International | false | false |
| 6 | 4 | The Good Shepherd | $525,502 | -31.4% | 199 | +2 | $2,640 | $1,548,431 | 2 | Paramount Pictures International | false | false |
| 7 | 5 | Miss Potter | $272,230 | -28.8% | 197 | -30 | $1,381 | $4,645,477 | 5 | Icon Film Distribution | false | false |
| 8 | 10 | Babel | $172,691 | -10.5% | 85 | -6 | $2,031 | $4,942,812 | 9 | United International Pictures | false | false |
| 9 | 12 | The Queen | $142,264 | -21.2% | 135 | +6 | $1,053 | $6,470,210 | 9 | Icon Film Distribution | false | false |
| 10 | - | The Illusionist | $123,938 | - | 92 | - | $1,347 | $153,461 | - | Roadshow Films | - | false |
| 11 | 6 | Hannibal Rising | $119,599 | -54.3% | 120 | -11 | $996 | $1,323,031 | 3 | Roadshow Films | false | false |
| 12 | 8 | The Pursuit of Happyness | $117,570 | -48.4% | 129 | -47 | $911 | $10,398,214 | 7 | Sony Pictures Releasing | false | false |
| 13 | - | Letters from Iwo Jima | $105,883 | - | 24 | - | $4,411 | $105,883 | 1 | Warner Bros. | true | false |
| 14 | 14 | Blood Diamond | $95,161 | -29.9% | 78 | -24 | $1,220 | $6,010,302 | 8 | Warner Bros. | false | false |
| 15 | 15 | The Last King of Scotland | $93,107 | -25% | 56 | -1 | $1,662 | $936,043 | 4 | 20th Century Fox International | false | false |
| 16 | 9 | Epic Movie | $91,435 | -58.2% | 119 | -58 | $768 | $4,972,022 | 5 | 20th Century Fox International | false | false |
| 17 | 7 | Deja Vu | $84,072 | -65.4% | 89 | -74 | $944 | $6,882,939 | 6 | Buena Vista International | false | false |
| 18 | 11 | Smokin' Aces | $83,807 | -54.8% | 93 | -47 | $901 | $1,033,449 | 3 | Paramount Pictures International | false | false |
| 19 | - | Venus | $72,734 | - | 20 | - | $3,636 | $83,756 | 1 | Icon Film Distribution | true | false |
