| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Stomp the Yard | $13,300,000 | $12,287,352 | -$1,012,648 | -7.6% | 2,051 | $41,564,000 | $40,550,946 | 2 | Screen Gems | - |
| 2 | 2 | - | Night at the Museum | $13,000,000 | $12,012,724 | -$987,276 | -7.6% | 3,483 | $205,840,000 | $204,852,656 | 5 | Twentieth Century Fox | - |
| 3 | 4 | +1 | Dreamgirls | $8,711,000 | $8,008,749 | -$702,251 | -8.1% | 2,214 | $78,118,000 | $77,415,704 | 6 | DreamWorks | - |
| 4 | 3 | -1 | The Hitcher | $8,234,000 | - | - | - | 2,831 | $8,234,000 | - | 1 | Rogue Pictures | - |
| 5 | 5 | - | The Pursuit of Happyness | $6,700,000 | $6,310,133 | -$389,867 | -5.8% | 3,066 | $146,511,000 | $146,121,200 | 6 | Sony Pictures Releasing | - |
| 6 | 6 | - | Freedom Writers | $5,564,000 | $5,207,062 | -$356,938 | -6.4% | 2,286 | $26,882,000 | $26,524,683 | 3 | Paramount Pictures | - |
| 7 | 7 | - | Pan's Labyrinth | $4,725,000 | $4,502,243 | -$222,757 | -4.7% | 609 | $10,155,000 | $9,932,414 | 4 | Picturehouse | - |
| 8 | 9 | +1 | The Queen | $3,700,000 | - | - | - | 1,586 | $35,857,000 | - | 17 | Miramax | - |
| 9 | 8 | -1 | Children of Men | $3,700,000 | $3,710,945 | +$10,945 | +0.3% | 1,524 | $27,481,000 | $27,491,508 | 4 | Universal Pictures | - |
| 10 | 10 | - | Arthur and the Invisibles | $3,105,000 | $3,080,698 | -$24,302 | -0.8% | 2,248 | $9,296,000 | $9,272,106 | 4 | Metro-Goldwyn-Mayer (MGM) | - |
| 11 | 11 | - | Alpha Dog | $2,900,000 | $2,990,995 | +$90,995 | +3.1% | 1,292 | $11,697,000 | $11,787,810 | 2 | Universal Pictures | - |
| 12 | 13 | +1 | Babel | $2,284,000 | $2,072,412 | -$211,588 | -9.3% | 889 | $23,870,000 | $23,658,420 | 13 | Paramount Vantage | - |
| 13 | 12 | -1 | Charlotte's Web | $2,268,000 | $2,335,120 | +$67,120 | +3% | 1,915 | $76,706,000 | $76,773,487 | 6 | Paramount Pictures | - |
| 14 | 14 | - | The Good Shepherd | $2,100,000 | $2,050,155 | -$49,845 | -2.4% | 1,571 | $57,652,000 | $57,602,410 | 5 | Universal Pictures | - |
| 15 | 16 | +1 | Blood Diamond | $1,860,000 | $1,744,497 | -$115,503 | -6.2% | 955 | $50,743,000 | $50,627,655 | 7 | Warner Bros. | - |
| 16 | 15 | -1 | Primeval | $1,827,000 | $1,878,287 | +$51,287 | +2.8% | 2,444 | $9,543,000 | $9,594,760 | 2 | Walt Disney Studios Motion Pictures | - |
| 17 | 17 | - | The Last King of Scotland | $1,755,000 | $1,609,920 | -$145,080 | -8.3% | 495 | $5,472,000 | $5,326,979 | 17 | Fox Searchlight Pictures | - |
| 18 | 18 | - | Rocky Balboa | $1,752,000 | $1,578,171 | -$173,829 | -9.9% | 1,450 | $67,899,000 | $67,725,170 | 5 | Metro-Goldwyn-Mayer (MGM) | - |
| 19 | 20 | +1 | We Are Marshall | $1,655,000 | $1,472,349 | -$182,651 | -11% | 1,440 | $41,261,000 | $41,078,532 | 5 | Warner Bros. | - |
| 20 | 21 | +1 | Letters from Iwo Jima | $1,515,000 | $1,355,466 | -$159,534 | -10.5% | 360 | $2,602,000 | $2,442,552 | 5 | Warner Bros. | - |
| 21 | 19 | -2 | Happily N'Ever After | $1,510,000 | $1,562,814 | +$52,814 | +3.5% | 1,758 | $13,310,000 | $13,918,125 | 3 | Lionsgate | - |
| 22 | 22 | - | Happy Feet | $1,350,000 | $1,308,288 | -$41,712 | -3.1% | 1,004 | $190,738,000 | $190,695,949 | 10 | Warner Bros. | - |
| 23 | 23 | - | Casino Royale | $1,300,000 | $1,192,435 | -$107,565 | -8.3% | 661 | $164,449,000 | $164,341,331 | 10 | Sony Pictures Releasing | - |
| 24 | 24 | - | Eragon | $1,250,000 | $1,175,713 | -$74,287 | -5.9% | 1,075 | $72,418,000 | $72,343,373 | 6 | Twentieth Century Fox | - |
| 25 | 25 | - | Notes on a Scandal | $1,230,000 | $1,167,702 | -$62,298 | -5.1% | 200 | $6,067,000 | $6,004,333 | 4 | Fox Searchlight Pictures | - |
| 26 | 26 | - | The Painted Veil | $933,000 | $903,477 | -$29,523 | -3.2% | 252 | $3,866,000 | $3,836,419 | 5 | Warner Independent Pictures (WIP) | - |
| 27 | 27 | - | Curse of the Golden Flower | $901,000 | - | - | - | 1,149 | $5,897,000 | - | 5 | Sony Pictures Classics | - |
| 28 | 28 | - | The Holiday | $750,000 | $682,075 | -$67,925 | -9.1% | 719 | $62,889,000 | $62,821,343 | 7 | Sony Pictures Releasing | - |
| 29 | 29 | - | Code Name: The Cleaner | $675,000 | $553,207 | -$121,793 | -18% | 675 | $7,958,000 | $7,835,856 | 3 | New Line Cinema | - |
| 30 | 30 | - | Volver | $598,000 | $535,947 | -$62,053 | -10.4% | 147 | $7,570,000 | $7,507,680 | 12 | Sony Pictures Classics | - |
| 31 | 32 | +1 | Apocalypto | $501,000 | $517,784 | +$16,784 | +3.4% | 349 | $49,782,000 | $49,799,017 | 7 | Walt Disney Studios Motion Pictures | - |
| 32 | 38 | +6 | Little Children | $200,000 | $184,844 | -$15,156 | -7.6% | 92 | $3,778,000 | $3,763,186 | 16 | New Line Cinema | - |
| 33 | 37 | +4 | Perfume: The Story of a Murderer | $180,000 | $188,409 | +$8,409 | +4.7% | 69 | $1,640,000 | $1,648,422 | 4 | DreamWorks | - |
| 34 | 39 | +5 | Miss Potter | $160,000 | $166,550 | +$6,550 | +4.1% | 38 | $577,000 | $583,223 | 4 | Metro-Goldwyn-Mayer (MGM) | - |
| 35 | 42 | +7 | Venus | $101,000 | $100,930 | -$70 | <0.1% | 12 | $326,000 | $326,105 | 5 | Miramax | - |
| 36 | 41 | +5 | The Good German | $100,000 | $109,897 | +$9,897 | +9.9% | 66 | $880,000 | $891,721 | 6 | Warner Bros. | - |
| 37 | 50 | +13 | God Grew Tired of Us | $44,400 | $39,045 | -$5,355 | -12.1% | 8 | $113,000 | $70,308 | 2 | Newmarket Films | - |
| 38 | 53 | +15 | The Italian | $24,300 | $23,290 | -$1,010 | -4.2% | 4 | $24,300 | $23,290 | 1 | Sony Pictures Classics | - |
