| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Night at the Museum | $24,000,000 | $23,743,960 | -$256,040 | -1.1% | 3,730 | $164,097,000 | $163,840,714 | 3 | Twentieth Century Fox | - |
| 2 | 2 | - | The Pursuit of Happyness | $13,000,000 | $12,880,926 | -$119,074 | -0.9% | 3,027 | $124,159,000 | $124,039,482 | 4 | Sony Pictures Releasing | - |
| 3 | 3 | - | Children of Men | $10,295,000 | $10,197,775 | -$97,225 | -0.9% | 1,209 | $11,902,000 | $11,805,273 | 2 | Universal Pictures | - |
| 4 | 4 | - | Freedom Writers | $9,705,000 | $9,405,582 | -$299,418 | -3.1% | 1,360 | $9,705,000 | $9,405,582 | 1 | Paramount Pictures | - |
| 5 | 5 | - | Dreamgirls | $8,825,000 | $8,663,380 | -$161,620 | -1.8% | 852 | $54,484,000 | $54,322,145 | 4 | DreamWorks | - |
| 6 | 6 | - | Happily N'Ever After | $6,800,000 | $6,608,244 | -$191,756 | -2.8% | 2,381 | $6,800,000 | $6,608,244 | 1 | Lionsgate | - |
| 7 | 7 | - | Charlotte's Web | $6,610,000 | $6,598,179 | -$11,821 | -0.2% | 3,303 | $66,975,000 | $66,963,119 | 4 | Paramount Pictures | - |
| 8 | 8 | - | The Good Shepherd | $6,536,000 | $6,446,345 | -$89,655 | -1.4% | 2,250 | $48,434,000 | $48,344,025 | 3 | Universal Pictures | - |
| 9 | 9 | - | Rocky Balboa | $6,268,000 | $6,017,649 | -$250,351 | -4% | 3,018 | $60,892,000 | $60,642,611 | 3 | Metro-Goldwyn-Mayer (MGM) | - |
| 10 | 10 | - | We Are Marshall | $5,130,000 | $4,875,400 | -$254,600 | -5% | 2,502 | $25,420,000 | $35,165,379 | 3 | Warner Bros. | - |
| 11 | 11 | - | Eragon | $4,600,000 | $4,810,405 | +$210,405 | +4.6% | 2,625 | $66,833,000 | $67,043,851 | 4 | Twentieth Century Fox | - |
| 12 | 12 | - | Code Name: The Cleaner | $4,300,000 | - | - | - | 1,736 | $4,300,000 | - | 1 | New Line Cinema | - |
| 13 | 14 | +1 | The Holiday | $4,000,000 | $3,845,411 | -$154,589 | -3.9% | 2,320 | $58,970,000 | $58,815,572 | 5 | Sony Pictures Releasing | - |
| 14 | 13 | -1 | Happy Feet | $4,000,000 | $4,004,462 | +$4,462 | +0.1% | 2,212 | $185,410,000 | $185,414,182 | 8 | Warner Bros. | - |
| 15 | 15 | - | Blood Diamond | $3,770,000 | $3,822,423 | +$52,423 | +1.4% | 1,510 | $43,842,000 | $43,894,082 | 5 | Warner Bros. | - |
| 16 | 16 | - | Casino Royale | $3,100,000 | $3,002,507 | -$97,493 | -3.1% | 1,266 | $159,935,000 | $159,837,718 | 8 | Sony Pictures Releasing | - |
| 17 | 17 | - | Black Christmas | $1,910,000 | $1,798,578 | -$111,422 | -5.8% | 1,504 | $15,335,000 | $15,224,364 | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 18 | 18 | - | Apocalypto | $1,601,000 | $1,762,525 | +$161,525 | +10.1% | 903 | $47,174,000 | $47,335,193 | 5 | Walt Disney Studios Motion Pictures | - |
| 19 | 19 | - | Notes on a Scandal | $1,100,000 | $1,125,281 | +$25,281 | +2.3% | 93 | $2,031,000 | $2,056,476 | 2 | Fox Searchlight Pictures | - |
| 20 | 20 | - | The Queen | $1,029,000 | - | - | - | 323 | $29,914,000 | - | 15 | Miramax | - |
| 21 | 22 | +1 | Thr3e | $740,000 | - | - | - | 458 | $740,000 | - | 1 | The Bigger Picture | - |
| 22 | 21 | -1 | Pan's Labyrinth | $727,000 | $763,795 | +$36,795 | +5.1% | 44 | $1,816,000 | $1,853,154 | 2 | Picturehouse | - |
| 23 | 23 | - | Volver | $607,000 | $596,869 | -$10,131 | -1.7% | 109 | $5,970,000 | $5,959,367 | 10 | Sony Pictures Classics | - |
| 24 | 24 | - | Perfume: The Story of a Murderer | $551,000 | $592,488 | +$41,488 | +7.5% | 280 | $649,000 | $690,534 | 2 | DreamWorks | - |
| 25 | 25 | - | The Painted Veil | $480,000 | $486,699 | +$6,699 | +1.4% | 72 | $1,245,000 | $1,251,473 | 3 | Warner Independent Pictures (WIP) | - |
| 26 | 27 | +1 | Babel | $464,000 | $454,022 | -$9,978 | -2.2% | 190 | $20,754,000 | $20,744,537 | 11 | Paramount Vantage | - |
| 27 | 26 | -1 | Borat | $460,000 | $467,034 | +$7,034 | +1.5% | 353 | $126,550,000 | $126,557,312 | 10 | Twentieth Century Fox | - |
| 28 | 29 | +1 | Curse of the Golden Flower | $354,000 | $335,759 | -$18,241 | -5.2% | 55 | $2,237,000 | $2,219,011 | 3 | Sony Pictures Classics | - |
| 29 | 37 | +8 | Miss Potter | $123,000 | $121,230 | -$1,770 | -1.4% | 26 | $141,000 | $138,785 | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 30 | 39 | +9 | The Good German | $80,000 | $86,958 | +$6,958 | +8.7% | 20 | $630,000 | $636,726 | 4 | Warner Bros. | - |
| 31 | 41 | +10 | Letters from Iwo Jima | $75,000 | $79,297 | +$4,297 | +5.7% | 5 | $475,000 | $472,372 | 3 | Warner Bros. | - |
| 32 | 52 | +20 | Venus | $25,900 | $27,195 | +$1,295 | +5% | 3 | $165,000 | $166,276 | 3 | Miramax | - |
| 33 | 54 | +21 | The Wedding Weekend | $20,300 | $23,719 | +$3,419 | +16.8% | 32 | - | $1,162,954 | 11 | The Weinstein Company | - |
| 34 | 62 | +28 | The Breed | $14,500 | - | - | - | - | $14,500 | - | 1 | First Look International | - |
| 35 | 74 | +39 | The Dead Girl | $4,700 | $4,789 | +$89 | +1.9% | 2 | $17,300 | $17,311 | 2 | First Look International | - |
