| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Casino Royale | $311,970 | -28.8% | 87 | -2 | $3,585 | $2,100,905 | 3 | Sony Pictures Releasing | false | false |
| 2 | - | Deja Vu | $161,986 | - | 45 | - | $3,599 | $161,986 | 1 | Buena Vista International | true | false |
| 3 | 2 | Eragon | $156,996 | -39.8% | 69 | - | $2,275 | $541,862 | 2 | 20th Century Fox International | false | false |
| 4 | - | Charlotte's Web | $135,860 | - | 59 | - | $2,302 | $135,860 | 1 | United International Pictures | true | false |
| 5 | 3 | The Holiday | $111,646 | -33.6% | 53 | +2 | $2,106 | $445,949 | 2 | United International Pictures | false | false |
| 6 | 5 | Flushed Away | $97,755 | +14.1% | 54 | -1 | $1,810 | $430,260 | 3 | United International Pictures | false | false |
| 7 | 4 | Borat | $73,726 | -41.4% | 48 | -2 | $1,535 | $1,920,705 | 5 | 20th Century Fox International | false | false |
| 8 | - | The Queen | $42,651 | - | 36 | - | $1,184 | $42,651 | 1 | Icon Film Distribution | true | false |
| 9 | 7 | The Santa Clause 3: The Escape Clause | $35,924 | +25.8% | 29 | -8 | $1,238 | $429,065 | 6 | Buena Vista International | false | false |
| 10 | - | Marie Antoinette | $26,940 | - | 16 | - | $1,683 | $26,940 | - | Sony Pictures Releasing | - | false |
| 11 | 6 | Material Girls | $25,724 | -28.3% | 30 | -4 | $857 | $97,744 | 2 | Hoyts Distribution | false | false |
| 12 | 9 | The Nativity Story | $19,376 | -1.9% | 17 | -19 | $1,139 | $163,781 | 4 | Roadshow Films | false | false |
| 13 | - | The Valet | $12,841 | - | 15 | - | $856 | $57,799 | 1 | Rialto Distribution | true | false |
| 14 | 8 | The Departed | $10,176 | -54.8% | 19 | -16 | $535 | $779,638 | 6 | Warner Bros. | false | false |
| 15 | - | Copying Beethoven | $8,081 | - | 16 | - | $505 | $8,081 | 1 | Hopscotch Films | true | false |
| 16 | 10 | Children of Men | $7,870 | -54.8% | 7 | -7 | $1,124 | $217,148 | 5 | United International Pictures | false | false |
| 17 | 12 | Kenny | $6,599 | -30% | 17 | +1 | $388 | $309,388 | 7 | Madman Entertainment | false | false |
| 18 | 11 | Crank | $2,226 | -84.7% | 6 | -14 | $371 | $28,936 | 4 | Hoyts Distribution | false | false |
| 19 | 19 | Five Days in September: The Rebirth of an Orchestra | $1,726 | -52% | 9 | - | $191 | $28,936 | 2 | Rialto Distribution | false | false |
| 20 | 14 | Unaccompanied Minors | $1,569 | -81.5% | 8 | -22 | $196 | $86,485 | 4 | Roadshow Films | false | false |
