| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Apocalypto | $14,166,000 | $15,005,604 | +$839,604 | +5.9% | 2,465 | $14,166,000 | $15,005,604 | 1 | Walt Disney Studios Motion Pictures | - |
| 2 | 3 | +1 | The Holiday | $13,500,000 | $12,778,913 | -$721,087 | -5.3% | 2,610 | $13,500,000 | $12,778,913 | 1 | Sony Pictures Releasing | - |
| 3 | 2 | -1 | Happy Feet | $12,718,000 | $12,904,413 | +$186,413 | +1.5% | 3,650 | $137,738,000 | $137,932,841 | 4 | Warner Bros. | - |
| 4 | 4 | - | Casino Royale | $8,800,000 | $8,926,207 | +$126,207 | +1.4% | 3,161 | $128,894,000 | $129,020,082 | 4 | Sony Pictures Releasing | - |
| 5 | 5 | - | Blood Diamond | $8,515,000 | $8,648,324 | +$133,324 | +1.6% | 1,910 | $8,515,000 | $8,648,324 | 1 | Warner Bros. | - |
| 6 | 7 | +1 | Unaccompanied Minors | $6,205,000 | $5,815,474 | -$389,526 | -6.3% | 2,775 | $6,205,000 | $5,815,474 | 1 | Warner Bros. | - |
| 7 | 6 | -1 | Deja Vu | $6,070,000 | $6,019,672 | -$50,328 | -0.8% | 2,742 | $53,046,000 | $52,995,929 | 3 | Walt Disney Studios Motion Pictures | - |
| 8 | 8 | - | The Nativity Story | $5,350,000 | - | - | - | 3,083 | $15,500,000 | - | 2 | New Line Cinema | - |
| 9 | 9 | - | Deck the Halls | $3,925,000 | $3,993,188 | +$68,188 | +1.7% | 2,766 | $30,076,000 | $30,144,903 | 3 | Twentieth Century Fox | - |
| 10 | 10 | - | The Santa Clause 3: The Escape Clause | $3,311,000 | $3,254,729 | -$56,271 | -1.7% | 2,226 | $77,240,000 | $77,184,019 | 6 | Walt Disney Studios Motion Pictures | - |
| 11 | 11 | - | Borat | $2,565,000 | $2,571,596 | +$6,596 | +0.3% | 1,594 | $120,260,000 | $120,266,165 | 6 | Twentieth Century Fox | - |
| 12 | 12 | - | Stranger Than Fiction | $1,500,000 | $1,425,717 | -$74,283 | -5% | 1,266 | $39,205,000 | $39,130,729 | 5 | Sony Pictures Releasing | - |
| 13 | 13 | - | Turistas | $1,335,000 | $1,418,457 | +$83,457 | +6.3% | 1,572 | $5,875,000 | $5,958,487 | 2 | Fox Atomic | - |
| 14 | 14 | - | The Queen | $905,000 | - | - | - | 628 | $24,577,000 | - | 11 | Miramax | - |
| 15 | 19 | +4 | Babel | $458,000 | $456,581 | -$1,419 | -0.3% | 373 | $17,607,000 | $17,605,771 | 7 | Paramount Vantage | - |
| 16 | 21 | +5 | Volver | $377,000 | $371,788 | -$5,212 | -1.4% | 44 | $2,381,000 | $2,375,995 | 6 | Sony Pictures Classics | - |
| 17 | 22 | +5 | For Your Consideration | $340,000 | $340,208 | +$208 | <0.1% | 295 | $4,871,000 | $4,871,038 | 4 | Warner Independent Pictures (WIP) | - |
| 18 | 24 | +6 | Guadalupe: El Milagro Y El Mensaje | $301,333 | - | - | - | 225 | $301,333 | - | 1 | Slowhand Cinema Releasing | - |
| 19 | 25 | +6 | Saw III | $230,000 | $297,153 | +$67,153 | +29.2% | 424 | $80,083,000 | $80,150,343 | 7 | Lionsgate | - |
| 20 | 27 | +7 | The History Boys | $211,000 | $201,791 | -$9,209 | -4.4% | 50 | $510,000 | $500,432 | 3 | Fox Searchlight Pictures | - |
| 21 | 33 | +12 | The Wedding Weekend | $85,000 | $88,624 | +$3,624 | +4.3% | 83 | - | $916,772 | 7 | The Weinstein Company | - |
| 22 | 50 | +28 | Shortbus | $28,200 | $28,611 | +$411 | +1.5% | 25 | $1,851,000 | $1,851,628 | 10 | THINKFilm | - |
| 23 | 52 | +29 | Inland Empire | $27,508 | - | - | - | 2 | $37,997 | - | 1 | 518 Media | - |
| 24 | 55 | +31 | 10 Items or Less | $23,400 | $22,108 | -$1,292 | -5.5% | 13 | $70,500 | $69,265 | 2 | THINKFilm | - |
| 25 | 53 | +28 | Screamers | $23,000 | $23,609 | +$609 | +2.6% | 4 | $23,000 | $23,609 | 1 | Maya Entertainment | - |
| 26 | 58 | +32 | Stormbreaker | $18,400 | $18,436 | +$36 | +0.2% | 95 | $678,000 | $677,646 | 10 | The Weinstein Company | - |
| 27 | 63 | +36 | Days of Glory | $11,000 | $10,996 | -$4 | <0.1% | 2 | $13,700 | $13,742 | 1 | The Weinstein Company | - |
| 28 | 71 | +43 | Off the Black | $8,000 | $6,763 | -$1,237 | -15.5% | 2 | $8,000 | $6,763 | 1 | THINKFilm | - |
| 29 | 64 | +35 | Ever Again | $7,400 | $10,802 | +$3,402 | +46% | 12 | $7,400 | $10,802 | 1 | Rocky Mountain Pictures | - |
| 30 | 110 | +80 | Christmas at Maxwell's | $1,700 | $809 | -$891 | -52.4% | 31 | $13,200 | $12,350 | 2 | Aloha Releasing Inc. | - |
