| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Happy Feet | $17,045,000 | $17,545,418 | +$500,418 | +2.9% | 3,804 | $121,000,000 | $121,501,018 | 3 | Warner Bros. | - |
| 2 | 2 | - | Casino Royale | $15,100,000 | $15,112,870 | +$12,870 | <0.1% | 3,386 | $115,863,000 | $115,876,024 | 3 | Sony Pictures Releasing | - |
| 3 | 3 | - | Deja Vu | $11,032,000 | $10,947,752 | -$84,248 | -0.8% | 3,108 | $44,091,000 | $44,007,448 | 2 | Walt Disney Studios Motion Pictures | - |
| 4 | 4 | - | The Nativity Story | $8,025,000 | - | - | - | 3,083 | $8,025,000 | - | 1 | New Line Cinema | - |
| 5 | 5 | - | Deck the Halls | $6,650,000 | $6,676,139 | +$26,139 | +0.4% | 3,205 | $24,991,000 | $25,017,188 | 2 | Twentieth Century Fox | - |
| 6 | 6 | - | The Santa Clause 3: The Escape Clause | $5,006,000 | $4,893,966 | -$112,034 | -2.2% | 2,617 | $73,152,000 | $73,039,485 | 5 | Walt Disney Studios Motion Pictures | - |
| 7 | 7 | - | Borat | $4,825,000 | $4,746,746 | -$78,254 | -1.6% | 2,237 | $116,320,000 | $116,241,347 | 5 | Twentieth Century Fox | - |
| 8 | 8 | - | Turistas | $3,540,000 | $3,582,554 | +$42,554 | +1.2% | 1,570 | $3,540,000 | $3,582,554 | 1 | Fox Atomic | - |
| 9 | 9 | - | Stranger Than Fiction | $3,400,000 | $3,356,324 | -$43,676 | -1.3% | 1,804 | $36,955,000 | $36,911,009 | 4 | Sony Pictures Releasing | - |
| 10 | 10 | - | Van Wilder: The Rise of Taj | $2,295,000 | $2,313,372 | +$18,372 | +0.8% | 1,979 | $2,295,000 | $2,313,372 | 1 | Metro-Goldwyn-Mayer (MGM) | - |
| 11 | 11 | - | Flushed Away | $2,275,000 | $2,205,862 | -$69,138 | -3% | 2,053 | $60,111,000 | $60,042,437 | 5 | DreamWorks | - |
| 12 | 12 | - | Bobby | $2,005,000 | $2,002,792 | -$2,208 | -0.1% | 1,670 | $9,209,000 | $9,207,037 | 3 | Metro-Goldwyn-Mayer (MGM) | - |
| 13 | 13 | - | The Fountain | $1,630,000 | $1,785,334 | +$155,334 | +9.5% | 1,472 | $8,086,000 | $8,241,535 | 2 | Warner Bros. | - |
| 14 | 14 | - | Tenacious D in the Pick of Destiny | $1,350,000 | - | - | - | 1,919 | $7,457,000 | - | 2 | New Line Cinema | - |
| 15 | 15 | - | The Queen | $1,350,000 | - | - | - | 712 | $23,071,000 | - | 10 | Miramax | - |
| 16 | 16 | - | Babel | $1,025,000 | $1,001,595 | -$23,405 | -2.3% | 609 | $16,798,000 | $16,774,393 | 6 | Paramount Vantage | - |
| 17 | 17 | - | For Your Consideration | $855,000 | $846,953 | -$8,047 | -0.9% | 625 | $4,284,000 | $4,275,796 | 3 | Warner Independent Pictures (WIP) | - |
| 18 | 18 | - | The Departed | $840,000 | $825,361 | -$14,639 | -1.7% | 572 | $118,017,000 | $118,002,823 | 9 | Warner Bros. | - |
| 19 | 19 | - | Saw III | $750,000 | $812,459 | +$62,459 | +8.3% | 553 | $79,482,000 | $79,544,001 | 6 | Lionsgate | - |
| 20 | 21 | +1 | Volver | $404,000 | $380,261 | -$23,739 | -5.9% | 30 | $1,894,000 | $1,869,832 | 5 | Sony Pictures Classics | - |
| 21 | 31 | +10 | The Wedding Weekend | $106,000 | $102,047 | -$3,953 | -3.7% | 84 | - | $780,914 | 6 | The Weinstein Company | - |
| 22 | 33 | +11 | The History Boys | $82,800 | $82,869 | +$69 | <0.1% | 8 | $265,000 | $264,558 | 2 | Fox Searchlight Pictures | - |
| 23 | 51 | +28 | Shortbus | $40,900 | $35,977 | -$4,923 | -12% | 26 | $1,809,000 | $1,804,234 | 9 | THINKFilm | - |
| 24 | 52 | +28 | 10 Items or Less | $40,200 | $35,929 | -$4,271 | -10.6% | 15 | $40,200 | $35,929 | 1 | THINKFilm | - |
| 25 | 56 | +31 | Keeping Mum | $12,000 | $16,198 | +$4,198 | +35% | 19 | $1,538,000 | $1,542,070 | 12 | THINKFilm | - |
| 26 | 63 | +37 | Candy | $10,700 | $9,844 | -$856 | -8% | 8 | $15,400 | $14,526 | 3 | THINKFilm | - |
| 27 | 65 | +38 | Christmas at Maxwell's | $8,200 | $8,375 | +$175 | +2.1% | 41 | $8,200 | $8,375 | 1 | Aloha Releasing Inc. | - |
