| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Departed | $173,269 | -37.4% | 65 | -10 | $2,665 | $987,015 | 3 | Warner Bros. | false | false |
| 2 | - | The Prestige | $142,793 | - | 31 | - | $4,606 | $142,793 | 1 | Warner Bros. | true | false |
| 3 | - | The Nativity Story | $67,326 | - | 53 | - | $1,270 | $67,326 | 1 | Distribution Company | true | false |
| 4 | 2 | The Illusionist | $64,636 | -19.8% | 29 | - | $2,228 | $918,019 | 7 | Alfa Films | false | false |
| 5 | 3 | Saw III | $49,721 | -33.8% | 49 | - | $1,014 | $875,647 | 5 | Buena Vista International | false | false |
| 6 | - | A Good Year | $37,363 | - | 30 | - | $1,245 | $37,363 | 1 | 20th Century Fox International | true | false |
| 7 | - | Shutter | $26,957 | - | 22 | - | $1,225 | $26,957 | 1 | Alfa Films | true | false |
| 8 | 5 | Open Season | $24,980 | -29.5% | 48 | +2 | $520 | $536,578 | 9 | Sony Pictures Releasing | false | false |
| 9 | 6 | Barnyard | $17,295 | -41.2% | 31 | - | $557 | $318,694 | 8 | United International Pictures | false | false |
| 10 | 9 | You, Me and Dupree | $11,632 | -50.6% | 29 | -1 | $401 | $525,177 | 10 | United International Pictures | false | false |
| 11 | 11 | World Trade Center | $10,399 | -44.6% | 35 | -5 | $297 | $361,614 | 7 | United International Pictures | false | false |
| 12 | - | Ugly Me | $8,265 | - | 22 | - | $375 | $8,265 | 1 | United International Pictures | true | false |
| 13 | 16 | All the King's Men | $7,572 | -9.7% | 12 | - | $631 | $75,365 | 4 | Sony Pictures Releasing | false | false |
| 14 | 8 | An Inconvenient Truth | $7,447 | -70.7% | 18 | -22 | $413 | $40,376 | 2 | United International Pictures | false | false |
| 15 | 12 | Pulse | $6,184 | -59.4% | 18 | -7 | $343 | $287,903 | 8 | Distribution Company | false | false |
| 16 | 10 | Fateless | $6,181 | -72.7% | 11 | -4 | $561 | $34,260 | 2 | Eurocine | false | false |
| 17 | 19 | Teo, cazador intergaláctico | $6,179 | -4.9% | 2 | - | $3,089 | $66,367 | 104 | Sony Pictures Releasing | false | false |
| 18 | 14 | The Covenant | $5,842 | -55.6% | 29 | - | $201 | $181,676 | 6 | Sony Pictures Releasing | false | false |
| 19 | 13 | The Guardian | $5,104 | -61.6% | 23 | -18 | $221 | $475,016 | 9 | Buena Vista International | false | false |
| 20 | 4 | The Texas Chainsaw Massacre: The Beginning | $4,999 | -88.8% | 20 | -9 | $249 | $60,333 | 2 | Distribution Company | false | false |
