| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Borat | $495,651 | - | 50 | - | $9,913 | $612,480 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | The Departed | $121,942 | -53.9% | 63 | - | $1,935 | $480,012 | 2 | Warner Bros. | false | false |
| 3 | 2 | The Santa Clause 3: The Escape Clause | $73,925 | -41.5% | 37 | - | $1,997 | $217,619 | 2 | Buena Vista International | false | false |
| 4 | - | Children of Men | $58,023 | - | 28 | - | $2,072 | $58,023 | 1 | United International Pictures | true | false |
| 5 | 5 | A Good Year | $46,137 | -51.3% | 56 | -4 | $823 | $362,664 | 3 | 20th Century Fox International | false | false |
| 6 | 7 | Kenny | $37,941 | -44.7% | 28 | +3 | $1,355 | $212,440 | 3 | Madman Entertainment | false | false |
| 7 | 6 | The Devil Wears Prada | $34,449 | -53.4% | 59 | -1 | $583 | $1,266,015 | 6 | 20th Century Fox International | false | false |
| 8 | - | Dhoom 2 | $34,448 | - | 5 | - | $6,889 | $34,448 | 1 | MG Distribution | true | false |
| 9 | - | Invincible | $33,952 | - | 17 | - | $1,997 | $33,952 | 1 | Buena Vista International | true | false |
| 10 | 4 | Jackass Number Two | $31,608 | -67.4% | 47 | - | $672 | $596,173 | 4 | United International Pictures | false | false |
| 11 | - | Flushed Away | $26,121 | - | 38 | - | $687 | $26,121 | - | United International Pictures | - | false |
| 12 | 10 | Beyond the Sea | $20,281 | -32.1% | 32 | +13 | $633 | $71,724 | 2 | Arkles Entertainment | false | false |
| 13 | 8 | Out of the Blue | $19,967 | -48.5% | 34 | +1 | $587 | $649,777 | 7 | Dendy Films | false | false |
| 14 | 9 | Little Miss Sunshine | $17,986 | -44.7% | 21 | -1 | $856 | $498,272 | 7 | 20th Century Fox International | false | false |
| 15 | 13 | An Inconvenient Truth | $11,415 | -45% | 20 | - | $570 | $636,841 | 11 | United International Pictures | false | false |
| 16 | 14 | The Wind that Shakes the Barley | $10,346 | -40.7% | 21 | +6 | $492 | $175,472 | 5 | Dendy Films | false | false |
| 17 | 15 | The White Massai | $6,950 | -44.2% | 12 | -2 | $579 | $127,324 | 4 | Hopscotch Films | false | false |
| 18 | 12 | Flags of Our Fathers | $6,081 | -75.9% | 20 | -24 | $304 | $222,594 | 4 | Warner Bros. | false | false |
| 19 | 11 | The Grudge 2 | $5,008 | -80.5% | 15 | -10 | $333 | $340,523 | 5 | Roadshow Films | false | false |
| 20 | 16 | Mrs Palfrey at the Claremont | $4,773 | -52.6% | 16 | -2 | $298 | $1,156,523 | 15 | Rialto Distribution | false | false |
