| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Happy Feet | $42,320,000 | $41,533,432 | -$786,568 | -1.9% | 3,804 | $42,320,000 | $41,533,432 | 1 | Warner Bros. | - |
| 2 | 2 | - | Casino Royale | $40,600,000 | $40,833,156 | +$233,156 | +0.6% | 3,434 | $40,600,000 | $40,833,156 | 1 | Sony Pictures Releasing | - |
| 3 | 3 | - | Borat | $14,350,000 | $14,602,874 | +$252,874 | +1.8% | 2,611 | $90,504,000 | $90,757,366 | 3 | Twentieth Century Fox | - |
| 4 | 4 | - | The Santa Clause 3: The Escape Clause | $8,218,000 | $8,302,661 | +$84,661 | +1% | 3,359 | $51,620,000 | $51,704,119 | 3 | Walt Disney Studios Motion Pictures | - |
| 5 | 6 | +1 | Flushed Away | $6,812,000 | $6,596,962 | -$215,038 | -3.2% | 3,307 | $48,803,000 | $48,588,533 | 3 | DreamWorks | - |
| 6 | 5 | -1 | Stranger Than Fiction | $6,600,000 | $6,605,197 | +$5,197 | <0.1% | 2,270 | $22,900,000 | $22,905,344 | 2 | Sony Pictures Releasing | - |
| 7 | 8 | +1 | Babel | $2,902,000 | $2,904,642 | +$2,642 | <0.1% | 1,251 | $12,013,000 | $12,016,104 | 4 | Paramount Vantage | - |
| 8 | 7 | -1 | Saw III | $2,800,000 | $2,916,062 | +$116,062 | +4.1% | 1,942 | $74,852,000 | $74,968,353 | 4 | Lionsgate | - |
| 9 | 9 | - | The Departed | $2,605,000 | $2,585,402 | -$19,598 | -0.8% | 1,611 | $113,861,000 | $113,841,430 | 7 | Warner Bros. | - |
| 10 | 10 | - | After Dark's Horror Fest: 8 Films to Die For | $2,482,000 | - | - | - | 488 | $2,482,000 | - | 1 | Freestyle Releasing | - |
| 11 | 11 | - | The Queen | $2,300,000 | - | - | - | 606 | $17,291,000 | - | 8 | Miramax | - |
| 12 | 12 | - | Let's Go to Prison | $2,108,000 | $2,220,050 | +$112,050 | +5.3% | 1,495 | $2,108,000 | $2,220,050 | 1 | Universal Pictures | - |
| 13 | 13 | - | The Prestige | $2,004,000 | $1,949,969 | -$54,031 | -2.7% | 1,470 | $49,418,000 | $49,363,657 | 5 | Walt Disney Studios Motion Pictures | - |
| 14 | 14 | - | The Return | $1,726,000 | - | - | - | 1,953 | $6,873,000 | - | 2 | Rogue Pictures | - |
| 15 | 15 | - | A Good Year | $1,625,000 | $1,602,385 | -$22,615 | -1.4% | 2,067 | $6,425,000 | $6,402,072 | 2 | Twentieth Century Fox | - |
| 16 | 16 | - | Flags of Our Fathers | $824,000 | $819,575 | -$4,425 | -0.5% | 1,049 | $32,675,000 | $32,670,358 | 5 | DreamWorks | - |
| 17 | 17 | - | Harsh Times | $475,000 | $495,756 | +$20,756 | +4.4% | 956 | $3,090,000 | $3,112,154 | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 18 | 20 | +2 | For Your Consideration | $394,000 | $372,012 | -$21,988 | -5.6% | 23 | $394,000 | $372,012 | 1 | Warner Independent Pictures (WIP) | - |
| 19 | 19 | - | Fast Food Nation | $390,000 | $410,804 | +$20,804 | +5.3% | 321 | $390,000 | $410,804 | 1 | Fox Searchlight Pictures | - |
| 20 | 21 | +1 | Flicka | $375,000 | $370,793 | -$4,207 | -1.1% | 624 | $20,156,000 | $20,151,771 | 5 | Twentieth Century Fox | - |
| 21 | 24 | +3 | Man of the Year | $290,000 | $271,255 | -$18,745 | -6.5% | 464 | $37,123,000 | $37,104,465 | 6 | Universal Pictures | - |
| 22 | 27 | +5 | One Night with the King | $205,000 | - | - | - | 229 | $13,113,000 | - | 6 | 8x Entertainment | - |
| 23 | 30 | +7 | The Wedding Weekend | $162,000 | $164,127 | +$2,127 | +1.3% | 71 | - | $436,400 | 4 | The Weinstein Company | - |
| 24 | 32 | +8 | Volver | $145,000 | $142,952 | -$2,048 | -1.4% | 6 | $683,000 | $680,896 | 3 | Sony Pictures Classics | - |
| 25 | 37 | +12 | Employee of the Month | $95,000 | $101,027 | +$6,027 | +6.3% | 149 | $28,359,000 | $28,364,748 | 7 | Lionsgate | - |
| 26 | 41 | +15 | Shortbus | $86,900 | $77,380 | -$9,520 | -11% | 52 | $1,633,000 | $1,623,034 | 7 | THINKFilm | - |
| 27 | 42 | +15 | Bobby | $67,000 | $69,039 | +$2,039 | +3% | 2 | $67,000 | $69,039 | 1 | Metro-Goldwyn-Mayer (MGM) | - |
| 28 | 43 | +15 | Copying Beethoven | $55,000 | $58,733 | +$3,733 | +6.8% | 29 | $153,000 | $157,187 | 2 | Metro-Goldwyn-Mayer (MGM) | - |
| 29 | 51 | +22 | Keeping Mum | $24,400 | $27,122 | +$2,722 | +11.2% | 28 | $1,464,000 | $1,467,021 | 10 | THINKFilm | - |
| 30 | 61 | +31 | The U.S. vs. John Lennon | $13,000 | $11,885 | -$1,115 | -8.6% | 29 | $1,088,000 | $1,087,205 | 10 | Lionsgate | - |
| 31 | 63 | +32 | Deliver Us from Evil | $10,000 | $11,085 | +$1,085 | +10.8% | 10 | $181,000 | $181,735 | 6 | Lionsgate | - |
| 32 | 84 | +52 | Color of the Cross | $3,700 | $4,200 | +$500 | +13.5% | 12 | $84,300 | $84,744 | 4 | Rocky Mountain Pictures | - |
