| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Jackass Number Two | $1,822,586 | - | 198 | - | $9,204 | $1,849,337 | 1 | United International Pictures | true | false |
| 2 | 1 | Saw III | $928,307 | -53% | 208 | - | $4,463 | $3,532,097 | 2 | Hoyts Distribution | false | false |
| 3 | - | A Good Year | $847,035 | - | 286 | - | $2,961 | $889,925 | 1 | 20th Century Fox International | true | false |
| 4 | 2 | The Departed | $528,613 | -35.9% | 235 | -34 | $2,249 | $7,470,376 | 5 | Warner Bros. | false | false |
| 5 | - | Lucky Number Slevin | $382,357 | - | 116 | - | $3,296 | $493,045 | 1 | Roadshow Films | true | false |
| 6 | 4 | Little Miss Sunshine | $312,087 | -32.8% | 133 | -1 | $2,346 | $3,621,105 | 5 | 20th Century Fox International | false | false |
| 7 | 3 | Flags of Our Fathers | $285,689 | -48.3% | 215 | +1 | $1,328 | $1,056,580 | 2 | Warner Bros. | false | false |
| 8 | 5 | The Devil Wears Prada | $226,093 | -44.4% | 200 | -64 | $1,130 | $12,290,440 | 8 | 20th Century Fox International | false | false |
| 9 | 9 | Kenny | $169,210 | -26.9% | 114 | -1 | $1,484 | $5,258,940 | 13 | Madman Entertainment | false | false |
| 10 | 6 | BoyTown | $159,416 | -56% | 168 | -34 | $948 | $2,255,294 | 4 | Roadshow Films | false | false |
| 11 | 8 | Children of Men | $141,586 | -48.7% | 114 | -50 | $1,241 | $1,972,091 | 4 | United International Pictures | false | false |
| 12 | 7 | The Grudge 2 | $139,821 | -51.6% | 133 | -27 | $1,051 | $1,251,921 | 3 | Roadshow Films | false | false |
| 13 | 10 | Step Up | $97,454 | -38.3% | 158 | +26 | $616 | $4,973,306 | 7 | United International Pictures | false | false |
| 14 | 11 | An Inconvenient Truth | $84,130 | -33.1% | 61 | -2 | $1,379 | $2,726,133 | 9 | United International Pictures | false | false |
| 15 | 15 | The Nightmare Before Christmas 2006 3D Release | $78,457 | -24.7% | 15 | - | $5,230 | $305,132 | 2 | Buena Vista International | false | false |
| 16 | 17 | Mrs Palfrey at the Claremont | $63,370 | -32% | 32 | - | $1,980 | $324,576 | 3 | Rialto Distribution | false | false |
| 17 | 14 | Garfield: A Tail of Two Kitties | $62,586 | -41.9% | 139 | -24 | $450 | $5,369,874 | 10 | 20th Century Fox International | false | false |
| 18 | - | Shortbus | $49,056 | - | 8 | - | $6,132 | $60,193 | 1 | Hopscotch Films | true | false |
| 19 | 19 | God on My Side | $47,893 | -0.5% | 17 | +3 | $2,817 | $155,230 | 2 | Hopscotch Films | false | false |
| 20 | 12 | Crank | $31,839 | -73.9% | 43 | -68 | $740 | $1,000,861 | 4 | Hoyts Distribution | false | false |
