| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Perfume: The Story of a Murderer | $5,518,058 | -17.9% | 774 | +1 | $7,129 | $28,035,544 | 3 | Constantin Film | false | false |
| 2 | - | Click | $2,096,987 | - | 627 | - | $3,344 | $2,096,987 | 1 | Sony Pictures Releasing | true | false |
| 3 | - | World Trade Center | $1,679,218 | - | 496 | - | $3,385 | $1,679,218 | 1 | United International Pictures | true | false |
| 4 | 2 | Cars | $1,244,611 | -16.4% | 805 | -9 | $1,546 | $10,027,270 | 4 | Buena Vista International | false | false |
| 5 | 3 | You, Me and Dupree | $791,123 | -33.3% | 348 | - | $2,273 | $2,273,239 | 2 | United International Pictures | false | false |
| 6 | 4 | Crank | $642,409 | -26.9% | 399 | - | $1,610 | $1,775,819 | 2 | Universum Film (UFA) | false | false |
| 7 | 5 | Grave Decisions | $419,287 | +13.6% | 100 | +2 | $4,192 | $4,584,317 | 7 | Movienet | false | false |
| 8 | - | TKKG: The Secret of the Mysterious Mind Machine | $371,659 | - | 453 | - | $820 | $371,659 | 1 | Constantin Film | true | false |
| 9 | 6 | The Trip to Panama | $277,084 | -20.4% | 557 | +4 | $497 | $725,443 | 2 | Warner Bros. | false | false |
| 10 | - | The Science of Sleep | $197,114 | - | 110 | - | $1,791 | $197,114 | 1 | Prokino Filmverleih | true | false |
| 11 | 8 | Pirates of the Caribbean: Dead Man's Chest | $189,184 | -27.5% | 227 | -160 | $833 | $60,238,685 | 10 | Buena Vista International | false | false |
| 12 | 7 | Miami Vice | $130,803 | -50.3% | 230 | -168 | $568 | $9,422,280 | 6 | United International Pictures | false | false |
| 13 | 12 | Emma's Bliss | $94,261 | -2.3% | 117 | -3 | $805 | $2,023,913 | 7 | Pandora Filmproduktion | false | false |
| 14 | 11 | Thank You for Smoking | $89,147 | -12.1% | 85 | -4 | $1,048 | $1,285,705 | 5 | 20th Century Fox International | false | false |
| 15 | 15 | Volver | $88,525 | +9.8% | 104 | -7 | $851 | $5,267,346 | 9 | TOBIS Film | false | false |
