| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | The Devil Wears Prada | $2,617,746 | +161.9% | 323 | +130 | $8,104 | $3,720,555 | 2 | 20th Century Fox International | false | false |
| 2 | - | Step Up | $1,285,611 | - | 154 | - | $8,348 | $1,285,611 | 1 | United International Pictures | true | false |
| 3 | 1 | Talladega Nights: The Ballad of Ricky Bobby | $765,191 | -40.8% | 2,890 | +2,601 | $264 | $2,674,453 | 2 | Sony Pictures Releasing | false | false |
| 4 | 3 | Monster House | $644,738 | -22.8% | 266 | +5 | $2,423 | $3,534,446 | 3 | Sony Pictures Releasing | false | false |
| 5 | 4 | Garfield: A Tail of Two Kitties | $577,371 | -7.6% | 204 | +3 | $2,830 | $2,295,966 | 4 | 20th Century Fox International | false | false |
| 6 | 5 | Barnyard | $408,218 | -10.4% | 205 | -1 | $1,991 | $1,405,363 | 2 | United International Pictures | false | false |
| 7 | - | The Wild | $352,493 | - | 253 | - | $1,393 | $1,024,822 | 1 | Buena Vista International | true | false |
| 8 | - | The Ant Bully | $250,041 | - | 211 | - | $1,185 | $706,731 | 1 | Warner Bros. | true | false |
| 9 | 8 | Stormbreaker | $225,981 | -33.9% | 179 | -11 | $1,262 | $1,047,973 | 2 | Roadshow Films | false | false |
| 10 | 9 | An Inconvenient Truth | $220,600 | -30% | 58 | -1 | $3,803 | $1,392,951 | 3 | United International Pictures | false | false |
| 11 | 6 | Nacho Libre | $213,506 | -47.8% | 220 | -12 | $970 | $2,002,381 | 3 | United International Pictures | false | false |
| 12 | 10 | Kenny | $195,412 | -33% | 98 | -5 | $1,994 | $3,067,067 | 7 | Madman Entertainment | false | false |
| 13 | 7 | John Tucker Must Die | $144,465 | -59.9% | 133 | -43 | $1,086 | $2,517,034 | 4 | 20th Century Fox International | false | false |
| 14 | - | Beerfest | $122,220 | - | 101 | - | $1,210 | $122,220 | 1 | Warner Bros. | true | false |
| 15 | 11 | Material Girls | $118,240 | -50.2% | 127 | -3 | $931 | $1,003,265 | 3 | Hoyts Distribution | false | false |
| 16 | 14 | The Wind that Shakes the Barley | $80,805 | -23% | 25 | +1 | $3,232 | $284,287 | 2 | Dendy Films | false | false |
| 17 | - | Aquamarine | $51,661 | - | 81 | - | $637 | $51,661 | 1 | 20th Century Fox International | true | false |
| 18 | 16 | Thank You for Smoking | $50,887 | -41.4% | 46 | -19 | $1,106 | $1,977,109 | 6 | 20th Century Fox International | false | false |
| 19 | 15 | Friends with Money | $45,847 | -53.9% | 38 | -6 | $1,206 | $1,240,411 | 5 | Roadshow Films | false | false |
| 20 | - | Pirates of the Caribbean: Dead Man's Chest | $40,749 | - | 24 | - | $1,697 | $28,477,460 | 13 | Buena Vista International | false | false |
