| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Over the Hedge | $581,668 | - | 102 | - | $5,702 | $744,595 | 1 | United International Pictures | true | false |
| 2 | 1 | Cars | $181,272 | -36.3% | 63 | -22 | $2,877 | $3,033,628 | 5 | Buena Vista International | false | false |
| 3 | 3 | Click | $86,651 | -6.7% | 27 | +1 | $3,209 | $588,015 | 4 | Sony Pictures Releasing | false | false |
| 4 | 2 | Uro | $83,936 | -28.8% | 46 | -10 | $1,824 | $1,724,755 | 5 | Sandrew Metronome Distribution Sverige AB | false | false |
| 5 | 6 | Volver | $73,256 | +5.9% | 16 | - | $4,578 | $491,759 | 4 | Sandrew Metronome Distribution Sverige AB | false | false |
| 6 | 4 | Sons | $66,659 | -20.6% | 30 | - | $2,221 | $208,350 | 2 | Sandrew Metronome Distribution Sverige AB | false | false |
| 7 | - | Heartbreak Hotel | $44,527 | - | 20 | - | $2,226 | $45,540 | 1 | Svensk Filmindustri (SF) | true | false |
| 8 | 7 | Reprise | $43,419 | -34.7% | 32 | -8 | $1,356 | $314,255 | 3 | Sony Pictures Releasing | false | false |
| 9 | 5 | My Super Ex-Girlfriend | $42,794 | -42.3% | 30 | - | $1,426 | $147,812 | 2 | 20th Century Fox International | false | false |
| 10 | 10 | Monster House | $31,967 | -12.2% | 29 | - | $1,102 | $83,083 | 2 | Sony Pictures Releasing | false | false |
| 11 | 8 | Trigger | $31,531 | -26.7% | 31 | -5 | $1,017 | $731,535 | 7 | Svensk Filmindustri (SF) | false | false |
| 12 | 11 | Pirates of the Caribbean: Dead Man's Chest | $28,323 | -19.1% | 14 | -3 | $2,023 | $8,182,838 | 11 | Buena Vista International | false | false |
| 13 | - | Fearless | $26,987 | - | 8 | - | $3,373 | $32,198 | 1 | Sony Pictures Releasing | true | false |
| 14 | 9 | Miami Vice | $23,047 | -40% | 31 | -6 | $743 | $1,547,099 | 7 | United International Pictures | false | false |
| 15 | 13 | United 93 | $22,901 | -25.9% | 20 | - | $1,145 | $630,908 | 6 | United International Pictures | false | false |
| 16 | 12 | Garfield: A Tail of Two Kitties | $16,551 | -52% | 18 | -9 | $919 | $1,802,045 | 10 | 20th Century Fox International | false | false |
| 17 | - | A Prairie Home Companion | $14,529 | - | 6 | - | $2,421 | $15,463 | 1 | Scanbox Entertainment | true | false |
| 18 | 16 | After the Wedding | $14,283 | -16.1% | 4 | -4 | $3,570 | $229,479 | 5 | Sony Pictures Releasing | false | false |
| 19 | 15 | An Inconvenient Truth | $14,058 | -18.3% | 20 | - | $702 | $95,864 | 3 | United International Pictures | false | false |
| 20 | 17 | The Break-Up | $11,464 | -7.8% | 23 | -2 | $498 | $956,916 | 8 | United International Pictures | false | false |
