| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Nacho Libre | $172,774 | - | 51 | - | $3,387 | $172,774 | 1 | United International Pictures | true | false |
| 2 | - | Garfield: A Tail of Two Kitties | $171,072 | - | 78 | - | $2,193 | $171,072 | 1 | 20th Century Fox International | true | false |
| 3 | - | Stick It | $115,787 | - | 30 | - | $3,859 | $115,787 | 1 | Roadshow Films | true | false |
| 4 | 1 | Mrs Palfrey at the Claremont | $85,410 | -27.6% | 41 | +2 | $2,083 | $706,877 | 5 | Rialto Distribution | false | false |
| 5 | - | An Inconvenient Truth | $54,316 | - | 10 | - | $5,431 | $121,209 | 1 | United International Pictures | true | false |
| 6 | 2 | Little Man | $47,375 | -52.5% | 43 | - | $1,101 | $378,370 | 3 | Sony Pictures Releasing | false | false |
| 7 | 6 | Wah-Wah | $39,632 | -11.3% | 11 | - | $3,602 | $134,578 | 2 | Hopscotch Films | false | false |
| 8 | 4 | Silent Hill | $34,899 | -31% | 28 | -1 | $1,246 | $226,917 | 3 | United International Pictures | false | false |
| 9 | 3 | Lady in the Water | $34,169 | -50.3% | 44 | - | $776 | $127,024 | 2 | Warner Bros. | false | false |
| 10 | 5 | DOA: Dead or Alive | $27,323 | -39.1% | 21 | +1 | $1,301 | $88,619 | 2 | United International Pictures | false | false |
| 11 | 10 | Thank You for Smoking | $27,028 | -17.3% | 10 | - | $2,702 | $216,159 | 4 | 20th Century Fox International | false | false |
| 12 | - | Monster House | $18,983 | - | 34 | - | $558 | $54,974 | - | Sony Pictures Releasing | - | false |
| 13 | 7 | Snakes on a Plane | $18,520 | -54.7% | 27 | -14 | $685 | $325,512 | 4 | Roadshow Films | false | false |
| 14 | - | The Wild | $17,722 | - | 34 | - | $521 | $17,722 | - | Buena Vista International | - | false |
| 15 | 8 | Clerks II | $16,008 | -57.6% | 26 | - | $615 | $68,704 | 2 | Roadshow Films | false | false |
| 16 | - | These Foolish Things | $15,043 | - | 10 | - | $1,504 | $15,043 | 1 | - | true | false |
| 17 | 15 | The Three Burials of Melquiades Estrada | $12,704 | -29.4% | 7 | -1 | $1,814 | $47,634 | 2 | Madman Entertainment | false | false |
| 18 | 12 | Pirates of the Caribbean: Dead Man's Chest | $12,076 | -62% | 23 | -21 | $525 | $4,598,022 | 11 | Buena Vista International | false | false |
| 19 | 14 | United 93 | $9,387 | -60% | 15 | -8 | $625 | $248,566 | 5 | United International Pictures | false | false |
| 20 | 16 | As It Is in Heaven | $9,194 | -46.7% | 13 | -1 | $707 | $441,540 | 38 | Rialto Distribution | false | false |
