| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Perfume: The Story of a Murderer | $9,698,326 | - | 700 | - | $13,854 | $9,698,326 | 1 | Constantin Film | true | false |
| 2 | 1 | Cars | $2,493,449 | -18.2% | 814 | - | $3,063 | $6,368,122 | 2 | Buena Vista International | false | false |
| 3 | 2 | Miami Vice | $547,702 | -42.4% | 445 | +4 | $1,230 | $8,783,110 | 4 | United International Pictures | false | false |
| 4 | 3 | Pirates of the Caribbean: Dead Man's Chest | $527,781 | -39.3% | 576 | -78 | $916 | $59,461,225 | 8 | Buena Vista International | false | false |
| 5 | 5 | Grave Decisions | $468,525 | +2.5% | 97 | +2 | $4,830 | $3,409,686 | 5 | Movienet | false | false |
| 6 | 4 | The Break-Up | $294,703 | -38.8% | 392 | -8 | $751 | $9,332,757 | 6 | United International Pictures | false | false |
| 7 | 9 | Garfield: A Tail of Two Kitties | $186,561 | -10.2% | 562 | -45 | $331 | $7,551,367 | 6 | 20th Century Fox International | false | false |
| 8 | 7 | Thank You for Smoking | $155,130 | -36.6% | 91 | +1 | $1,704 | $970,140 | 3 | 20th Century Fox International | false | false |
| 9 | 12 | Volver | $126,046 | -34.5% | 115 | - | $1,096 | $4,977,360 | 7 | TOBIS Film | false | false |
| 10 | 6 | Snakes on a Plane | $122,468 | -60.4% | 278 | -1 | $440 | $509,539 | 2 | Warner Bros. | false | false |
| 11 | 13 | Emma's Bliss | $114,721 | -24% | 120 | +5 | $956 | $1,729,971 | 5 | Pandora Filmproduktion | false | false |
| 12 | 11 | Bandidas | $108,521 | -47.1% | 184 | - | $589 | $976,026 | 3 | Universum Film (UFA) | false | false |
| 13 | 14 | Hui Buh: Das Schlossgespenst | $103,441 | -15.7% | 436 | -133 | $237 | $12,886,988 | 9 | Constantin Film | false | false |
| 14 | 15 | Monster House | $83,910 | -19.2% | 287 | -14 | $292 | $1,251,674 | 4 | Sony Pictures Releasing | false | false |
| 15 | 10 | Lady in the Water | $79,111 | -61.7% | 123 | -2 | $643 | $821,423 | 3 | Warner Bros. | false | false |
