| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Snakes on a Plane | $114,879 | - | 41 | - | $2,801 | $114,879 | 1 | Roadshow Films | true | false |
| 2 | 5 | Mrs Palfrey at the Claremont | $103,787 | +39.8% | 33 | +5 | $3,145 | $242,550 | 2 | Rialto Distribution | false | false |
| 3 | 1 | My Super Ex-Girlfriend | $83,920 | -32.9% | 40 | - | $2,098 | $240,716 | 2 | 20th Century Fox International | false | false |
| 4 | 3 | Hoodwinked! | $73,566 | -12.1% | 49 | -1 | $1,501 | $520,130 | 4 | Roadshow Films | false | false |
| 5 | 4 | Pirates of the Caribbean: Dead Man's Chest | $65,906 | -20.8% | 64 | - | $1,029 | $4,263,528 | 8 | Buena Vista International | false | false |
| 6 | 2 | Miami Vice | $57,028 | -42.8% | 43 | -2 | $1,326 | $505,912 | 3 | United International Pictures | false | false |
| 7 | - | Fearless | $51,729 | - | 19 | - | $2,722 | $66,791 | 1 | United International Pictures | true | false |
| 8 | 6 | United 93 | $48,634 | -21.2% | 25 | - | $1,945 | $134,014 | 2 | United International Pictures | false | false |
| 9 | 7 | You, Me and Dupree | $37,848 | -26.8% | 38 | -3 | $996 | $670,058 | 5 | United International Pictures | false | false |
| 10 | - | Thank You for Smoking | $37,683 | - | 10 | - | $3,768 | $71,092 | 1 | 20th Century Fox International | true | false |
| 11 | 8 | Take the Lead | $25,347 | -26.4% | 34 | -8 | $745 | $1,132,573 | 9 | Roadshow Films | false | false |
| 12 | 10 | As It Is in Heaven | $15,372 | -12% | 15 | - | $1,024 | $364,461 | 35 | Rialto Distribution | false | false |
| 13 | 9 | The Lake House | $14,640 | -29.3% | 20 | -9 | $732 | $435,430 | 6 | Roadshow Films | false | false |
| 14 | 13 | Ballets Russes | $9,946 | -5.5% | 4 | - | $2,486 | $38,213 | 3 | Hopscotch Films | false | false |
| 15 | - | Kabhi Alvida Naa Kehna | $9,450 | - | 5 | - | $1,890 | $81,577 | 1 | MG Distribution | true | false |
| 16 | 14 | Breakfast on Pluto | $8,144 | -4.2% | 12 | - | $678 | $81,697 | 5 | Dendy Films | false | false |
| 17 | 11 | Over the Hedge | $7,948 | -42.5% | 43 | -14 | $184 | $2,050,267 | 10 | United International Pictures | false | false |
| 18 | 20 | Confetti | $5,025 | -5.5% | 16 | - | $314 | $118,948 | 6 | 20th Century Fox International | false | false |
| 19 | 16 | Cars | $4,889 | -27.2% | 29 | -6 | $168 | $2,134,640 | 12 | Buena Vista International | false | false |
| 20 | 12 | Superman Returns | $4,421 | -66% | 14 | -14 | $315 | $1,425,056 | 9 | Warner Bros. | false | false |
