| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Da Vinci Code | $1,132,738 | -26.1% | 129 | - | $8,780 | $4,050,202 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | X-Men: The Last Stand | $524,232 | - | 94 | - | $5,576 | $976,740 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Mission: Impossible III | $188,750 | -7.4% | 86 | -11 | $2,194 | $1,936,476 | 4 | United International Pictures | false | false |
| 4 | 3 | Ice Age: The Meltdown | $119,528 | +3% | 70 | -9 | $1,707 | $5,894,495 | 9 | 20th Century Fox International | false | false |
| 5 | 4 | Heartbreak Hotel | $57,565 | -0.7% | 52 | -7 | $1,107 | $4,575,940 | 10 | Svensk Filmindustri (SF) | false | false |
| 6 | 5 | Scary Movie 4 | $36,337 | -11.8% | 35 | - | $1,038 | $973,099 | 7 | Buena Vista International | false | false |
| 7 | 6 | Inside Man | $13,664 | -10.1% | 19 | -11 | $719 | $1,009,321 | 9 | United International Pictures | false | false |
| 8 | 11 | Lassie | $13,591 | +32.1% | 22 | -1 | $617 | $213,065 | 8 | Svensk Filmindustri (SF) | false | false |
| 9 | 8 | V for Vendetta | $11,680 | -6% | 11 | -4 | $1,061 | $1,574,217 | 11 | Sandrew Metronome Distribution Sverige AB | false | false |
| 10 | 10 | When a Stranger Calls | $10,962 | +3.3% | 9 | -9 | $1,218 | $357,617 | 8 | Sony Pictures Releasing | false | false |
| 11 | 12 | Brokeback Mountain | $10,014 | +7.6% | 18 | -2 | $556 | $2,224,711 | 17 | Sandrew Metronome Distribution Sverige AB | false | false |
| 12 | 7 | Walk the Line | $9,567 | -34% | 18 | -10 | $531 | $1,624,854 | 17 | 20th Century Fox International | false | false |
| 13 | 13 | Stoned | $7,946 | +9.2% | 18 | -2 | $441 | $63,442 | 4 | NonStop Entertainment | false | false |
| 14 | 9 | Big Momma's House 2 | $7,276 | -40.8% | 4 | -10 | $1,819 | $377,793 | 8 | 20th Century Fox International | false | false |
| 15 | 17 | Firewall | $5,015 | +31.8% | 9 | - | $557 | $171,669 | 6 | Sandrew Metronome Distribution Sverige AB | false | false |
| 16 | 18 | Get Rich or Die Tryin' | $4,748 | +27.1% | 5 | - | $949 | $65,536 | 5 | United International Pictures | false | false |
| 17 | - | The Matador | $4,394 | - | 9 | - | $488 | $82,181 | 6 | Scanbox Entertainment | false | false |
| 18 | 16 | Syriana | $4,242 | +10.4% | 9 | +1 | $471 | $512,589 | 12 | Sandrew Metronome Distribution Sverige AB | false | false |
| 19 | - | Tristram Shandy | $3,857 | - | 4 | - | $964 | $57,673 | 6 | Atlantic Film | false | false |
