| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Mission: Impossible III | $404,813 | -26.2% | 109 | -19 | $3,713 | $1,225,912 | 2 | United International Pictures | false | false |
| 2 | 2 | Ice Age 2: The Meltdown | $152,815 | -50% | 195 | - | $783 | $6,825,766 | 7 | 20th Century Fox International | false | false |
| 3 | 3 | Scary Movie 4 | $86,175 | -31% | 80 | - | $1,077 | $2,011,659 | 5 | Buena Vista International | false | false |
| 4 | 4 | Lucky Number Slevin | $52,075 | -7.3% | 40 | - | $1,301 | $489,308 | 4 | Independent Films | false | false |
| 5 | 5 | Inside Man | $48,119 | -8.1% | 65 | - | $740 | $2,068,142 | 8 | United International Pictures | false | false |
| 6 | 7 | Memoirs of a Geisha | $44,503 | +1.2% | 35 | - | $1,271 | $837,048 | 6 | Sony Pictures Releasing | false | false |
| 7 | - | Last Holiday | $33,418 | - | 15 | - | $2,227 | $70,192 | 1 | United International Pictures | true | false |
| 8 | 6 | The Wild | $32,732 | -31.4% | 78 | - | $419 | $329,008 | 4 | Buena Vista International | false | false |
| 9 | - | Hoodwinked! | $25,243 | - | 35 | - | $721 | $41,953 | 1 | RCV Film Distribution | true | false |
| 10 | 10 | Final Destination 3 | $22,487 | -19.6% | 47 | +10 | $478 | $686,394 | 6 | RCV Film Distribution | false | false |
| 11 | 9 | Failure to Launch | $22,487 | -20.2% | 47 | +1 | $478 | $686,394 | 6 | United International Pictures | false | false |
| 12 | 8 | Asterix and the Vikings | $17,706 | -40.1% | 60 | - | $295 | $280,847 | 4 | Independent Films | false | false |
| 13 | 12 | V for Vendetta | $17,020 | -20.9% | 24 | -9 | $709 | $260,847 | 7 | Warner Bros. | false | false |
| 14 | - | The Weather Man | $15,695 | - | 12 | - | $1,307 | $26,443 | 1 | United International Pictures | true | false |
| 15 | 15 | The White Massai | $15,673 | +44.8% | 13 | +1 | $1,205 | $244,070 | 9 | Benelux Film Distributors | false | false |
| 16 | 11 | The Little Polar Bear 2: The Mysterious Island | $13,616 | -50.1% | 81 | +2 | $168 | $205,389 | 3 | Warner Bros. | false | false |
| 17 | 14 | Brokeback Mountain | $13,228 | -2.7% | 28 | -2 | $472 | $1,952,458 | 13 | A-Film Distribution | false | false |
| 18 | 13 | Tristan + Isolde | $11,221 | -34.7% | 26 | -9 | $431 | $214,347 | 4 | Benelux Film Distributors | false | false |
| 19 | 17 | Capote | $10,069 | +11.1% | 8 | - | $1,258 | $269,752 | 8 | Sony Pictures Releasing | false | false |
| 20 | 18 | The World's Fastest Indian | $6,621 | -2.1% | 10 | - | $662 | $52,141 | 2 | Independent Films | false | false |
