Domestic 2006 Weekend 15
April 14-17, 2006 - Easter weekend
Key:New This WeekEstimated
| Rank | LW | Release | Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | - | Scary Movie 4 | $44,196,859 | - | 3,602 | - | $12,270 | $44,196,859 | 1 | - |
| 2 | - | Ice Age: The Meltdown | $23,114,420 | - | 3,873 | - | $5,968 | $150,314,711 | 3 | Twentieth Century Fox |
| 3 | - | The Benchwarmers | $11,381,434 | - | 3,282 | - | $3,467 | $37,350,065 | 2 | Revolution Studios |
| 4 | - | The Wild | $11,295,457 | - | 2,854 | - | $3,957 | $11,295,457 | 1 | Walt Disney Studios Motion Pictures |
| 5 | - | Take the Lead | $7,648,000 | - | 3,009 | - | $2,541 | $23,465,000 | 2 | New Line Cinema |
| 6 | - | Inside Man | $7,071,835 | - | 2,477 | - | $2,855 | $76,065,200 | 4 | Universal Pictures |
| 7 | - | Lucky Number Slevin | $5,305,345 | - | 1,989 | - | $2,667 | $14,849,692 | 2 | - |
| 8 | - | Thank You for Smoking | $4,911,551 | - | 1,015 | - | $4,838 | $11,960,020 | 5 | - |
| 9 | - | Failure to Launch | $2,895,411 | - | 1,950 | - | $1,484 | $83,466,647 | 6 | Paramount Pictures |
| 10 | - | V for Vendetta | $2,496,575 | - | 1,380 | - | $1,809 | $66,309,991 | 5 | Warner Bros. |
| 11 | - | ATL | $1,573,786 | - | 1,315 | - | $1,196 | $19,883,445 | 3 | Warner Bros. |
| 12 | - | Phat Girlz | $1,501,391 | - | 1,060 | - | $1,416 | $5,498,130 | 2 | - |
| 13 | - | She's the Man | $1,115,089 | - | 2,026 | - | $550 | $31,969,625 | 5 | DreamWorks |
| 14 | - | My Brother's Wife | $1,107,583 | - | 206 | - | $5,376 | $1,107,583 | 1 | Lionsgate Films |
| 15 | - | Stay Alive | $826,587 | - | 1,039 | - | $795 | $22,176,487 | 4 | Walt Disney Studios Motion Pictures |
| 16 | - | Friends with Money | $808,000 | - | 42 | - | $19,238 | $1,603,000 | 2 | Sony Pictures Classics |
| 17 | - | Larry the Cable Guy: Health Inspector | $738,913 | - | 976 | - | $757 | $14,832,895 | 4 | Lionsgate Films |
| 18 | - | Deep Sea | $497,329 | - | 46 | - | $10,811 | $6,081,074 | 7 | Warner Bros. |
| 19 | - | The Shaggy Dog | $467,580 | - | 748 | - | $625 | $56,804,255 | 6 | Walt Disney Studios Motion Pictures |
| 20 | - | The Hills Have Eyes | $366,865 | - | 357 | - | $1,027 | $40,978,021 | 6 | - |
| 21 | - | Slither | $352,590 | - | 511 | - | $690 | $7,579,600 | 3 | Universal Pictures |
| 22 | - | Brick | $259,000 | - | 45 | - | $5,755 | $660,000 | 3 | Focus Features |
| 23 | - | The Pink Panther | $225,929 | - | 343 | - | $658 | $82,226,474 | 10 | Sony Pictures Releasing |
| 24 | - | Preaching to the Choir | $209,000 | - | 143 | - | $1,461 | $209,000 | 1 | Freestyle Releasing |
| 25 | - | Basic Instinct 2 | $177,461 | - | 323 | - | $549 | $5,851,188 | 3 | Sony Pictures Releasing |
| 26 | - | Big Momma's House 2 | $174,463 | - | 168 | - | $1,038 | $69,787,522 | 12 | Twentieth Century Fox |
| 27 | - | Firewall | $172,197 | - | 292 | - | $589 | $48,369,950 | 10 | Warner Bros. |
| 28 | - | Curious George | $145,685 | - | 310 | - | $469 | $58,021,160 | 10 | Universal Pictures |
| 29 | - | 16 Blocks | $133,789 | - | 140 | - | $955 | $36,223,911 | 7 | Warner Bros. |
| 30 | - | Date Movie | $129,477 | - | 169 | - | $766 | $48,235,644 | 9 | Twentieth Century Fox |
| 31 | - | Nanny McPhee | $125,125 | - | 197 | - | $635 | $46,889,265 | 12 | Universal Pictures |
| 32 | - | Hoodwinked! | $115,778 | - | 201 | - | $576 | $51,179,136 | 18 | The Weinstein Company |
| 33 | - | Aquamarine | $81,582 | - | 133 | - | $613 | $18,383,607 | 7 | Twentieth Century Fox |
| 34 | - | Hard Candy | $64,144 | - | 2 | - | $32,072 | $64,144 | 1 | Lionsgate Films |
| 35 | - | Neil Young: Heart of Gold | $61,761 | - | 61 | - | $1,012 | $1,604,375 | 10 | Paramount Classics |
| 36 | - | Mrs. Henderson Presents | $59,251 | - | 74 | - | $800 | $10,848,535 | 19 | The Weinstein Company |
| 37 | - | Madea's Family Reunion | $44,694 | - | 73 | - | $612 | $63,131,351 | 8 | Lionsgate Films |
| 38 | - | Cheaper by the Dozen 2 | $40,555 | - | 43 | - | $943 | $82,528,324 | 17 | Twentieth Century Fox |
| 39 | - | Transamerica | $38,544 | - | 44 | - | $876 | $8,834,885 | 20 | The Weinstein Company |
| 40 | - | Syriana | $30,169 | - | 52 | - | $580 | $50,818,353 | 21 | Warner Bros. |
| 41 | - | Walk the Line | $19,800 | - | 23 | - | $860 | $119,489,415 | 22 | Twentieth Century Fox |
| 42 | - | Ask the Dust | $17,068 | - | 46 | - | $371 | $712,860 | 6 | Paramount Classics |
| 43 | - | The Libertine | $12,118 | - | 24 | - | $504 | $4,831,254 | 21 | The Weinstein Company |
| 44 | - | Duck Season 2005 Re-release | $6,893 | - | 17 | - | $405 | $135,276 | 6 | Warner Independent Pictures (WIP) |
| 45 | - | Night Watch 2005 Re-release | $5,971 | - | 11 | - | $542 | $1,476,321 | 9 | - |
