| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Wallace & Gromit: The Curse of the Were-Rabbit | $16,100,000 | $16,025,987 | -$74,013 | -0.5% | 3,645 | $16,121,000 | $16,047,174 | 1 | DreamWorks Distribution | - |
| 2 | 2 | - | Flightplan | $10,788,000 | $10,764,440 | -$23,560 | -0.2% | 3,323 | $60,940,000 | $60,916,649 | 3 | Walt Disney Studios Motion Pictures | - |
| 3 | 3 | - | In Her Shoes | $10,025,000 | $10,017,575 | -$7,425 | <0.1% | 2,808 | $10,025,000 | $10,017,575 | 1 | Twentieth Century Fox | - |
| 4 | 4 | - | Two for the Money | $8,380,000 | $8,703,240 | +$323,240 | +3.9% | 2,391 | $8,380,000 | $8,703,240 | 1 | Universal Pictures | - |
| 5 | 5 | - | The Gospel | $8,000,000 | $7,523,571 | -$476,429 | -6% | 969 | $8,000,000 | $7,523,571 | 1 | Screen Gems | - |
| 6 | 6 | - | Corpse Bride | $6,540,000 | $6,511,336 | -$28,664 | -0.4% | 3,004 | $42,145,000 | $42,116,028 | 4 | Warner Bros. | - |
| 7 | 7 | - | Waiting... | $5,700,000 | $6,021,106 | +$321,106 | +5.6% | 1,652 | $5,700,000 | $6,021,106 | 1 | Lionsgate | - |
| 8 | 9 | +1 | A History of Violence | $5,125,000 | - | - | - | 1,340 | $16,697,000 | - | 3 | New Line Cinema | - |
| 9 | 8 | -1 | Serenity | $4,925,000 | $5,352,090 | +$427,090 | +8.7% | 2,189 | $17,594,000 | $18,020,875 | 2 | Universal Pictures | - |
| 10 | 10 | - | Into the Blue | $4,800,000 | $4,830,342 | +$30,342 | +0.6% | 2,789 | $13,873,000 | $13,903,087 | 2 | Sony Pictures Releasing | - |
| 11 | 11 | - | The Greatest Game Ever Played | $4,012,000 | $3,905,532 | -$106,468 | -2.7% | 1,810 | $8,788,000 | $8,680,794 | 2 | Walt Disney Studios Motion Pictures | - |
| 12 | 12 | - | Just Like Heaven | $3,400,000 | $3,453,588 | +$53,588 | +1.6% | 2,307 | $43,568,000 | $43,621,756 | 4 | DreamWorks Distribution | - |
| 13 | 13 | - | The Exorcism of Emily Rose | $2,500,000 | $2,442,028 | -$57,972 | -2.3% | 1,827 | $72,189,000 | $72,130,811 | 5 | Screen Gems | - |
| 14 | 15 | +1 | Roll Bounce | $1,650,000 | $1,742,119 | +$92,119 | +5.6% | 888 | $15,047,000 | $15,139,600 | 3 | Fox Searchlight Pictures | - |
| 15 | 16 | +1 | Proof | $1,552,000 | - | - | - | 517 | $4,458,000 | - | 4 | Miramax | - |
| 16 | 17 | +1 | The Constant Gardener | $809,000 | - | - | - | 469 | $31,209,000 | - | 6 | Focus Features | - |
| 17 | 18 | +1 | Lord of War | $675,000 | $680,766 | +$5,766 | +0.9% | 550 | $23,271,000 | $23,276,743 | 4 | Lionsgate | - |
| 18 | 19 | +1 | March of the Penguins | $430,000 | $473,074 | +$43,074 | +10% | 469 | $75,445,000 | $75,392,512 | 16 | Warner Independent Pictures (WIP) | - |
| 19 | 21 | +2 | Good Night, and Good Luck. | $420,000 | $421,446 | +$1,446 | +0.3% | 11 | $420,000 | $421,446 | 1 | Warner Independent Pictures (WIP) | - |
| 20 | 22 | +2 | Capote | $414,000 | - | - | - | 24 | $905,000 | - | 2 | Sony Pictures Classics | - |
| 21 | 24 | +3 | An Unfinished Life | $401,000 | $385,984 | -$15,016 | -3.7% | 428 | $8,279,000 | $8,264,735 | 5 | Miramax | - |
| 22 | 26 | +4 | Thumbsucker | $341,000 | $328,552 | -$12,448 | -3.7% | 330 | $850,000 | $837,473 | 4 | Sony Pictures Classics | - |
| 23 | 27 | +4 | Wedding Crashers | $320,000 | $319,913 | -$87 | <0.1% | 360 | $207,090,000 | $207,090,289 | 13 | New Line Cinema | - |
| 24 | 29 | +5 | Cry Wolf | $240,000 | $285,420 | +$45,420 | +18.9% | 258 | $9,496,000 | $9,540,933 | 4 | Rogue Pictures | - |
| 25 | 33 | +8 | Everything Is Illuminated | $225,000 | $220,978 | -$4,022 | -1.8% | 85 | $751,000 | $747,435 | 4 | Warner Independent Pictures (WIP) | - |
| 26 | 37 | +11 | Broken Flowers | $131,000 | $134,864 | +$3,864 | +2.9% | 152 | $13,441,000 | $13,444,579 | 10 | Focus Features | - |
| 27 | 35 | +8 | Separate Lies | $128,000 | $139,175 | +$11,175 | +8.7% | 59 | $284,000 | $295,153 | 4 | Fox Searchlight Pictures | - |
| 28 | 38 | +10 | The Squid and the Whale | $124,000 | $129,844 | +$5,844 | +4.7% | 4 | $148,000 | $154,474 | 1 | IDP Distribution | - |
| 29 | 41 | +12 | The Prize Winner of Defiance, Ohio | $107,000 | $106,439 | -$561 | -0.5% | 41 | $328,000 | $327,969 | 2 | DreamWorks Distribution | - |
| 30 | 44 | +14 | Junebug | $100,000 | $95,231 | -$4,769 | -4.8% | 84 | $2,421,000 | $2,416,555 | 10 | Sony Pictures Classics | - |
| 31 | 46 | +15 | Mirrormask | $96,000 | $93,539 | -$2,461 | -2.6% | 24 | $283,000 | $280,791 | 2 | IDP Distribution | - |
| 32 | 47 | +15 | Grizzly Man | $85,000 | $76,403 | -$8,597 | -10.1% | 62 | $2,791,000 | $2,782,496 | 9 | Lionsgate | - |
| 33 | 50 | +17 | The Aristocrats | $62,500 | $53,461 | -$9,039 | -14.5% | 60 | $6,142,000 | $6,132,550 | 11 | THINKFilm | - |
| 34 | 57 | +23 | G | $37,400 | $32,927 | -$4,473 | -12% | 27 | $608,000 | $603,309 | 4 | Aloha Releasing Inc. | - |
| 35 | 59 | +24 | Little Manhattan | $30,800 | $30,708 | -$92 | -0.3% | 2 | $80,600 | $81,299 | 2 | Twentieth Century Fox | - |
| 36 | 65 | +29 | Green Street Hooligans | $23,800 | $23,143 | -$657 | -2.8% | 23 | $277,000 | $276,465 | 5 | Freestyle Releasing | - |
| 37 | 66 | +29 | The Man | $13,000 | $20,322 | +$7,322 | +56.3% | 58 | $8,319,000 | $8,326,035 | 5 | New Line Cinema | - |
