| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Flightplan | $15,038,000 | $14,805,739 | -$232,261 | -1.5% | 3,424 | $46,145,000 | $45,912,018 | 2 | Walt Disney Studios Motion Pictures | - |
| 2 | 2 | - | Serenity | $10,141,000 | $10,086,680 | -$54,320 | -0.5% | 2,188 | $10,141,000 | $10,086,680 | 1 | Universal Pictures | - |
| 3 | 3 | - | Corpse Bride | $9,755,000 | $10,033,257 | +$278,257 | +2.9% | 3,204 | $32,910,000 | $33,188,109 | 3 | Warner Bros. | - |
| 4 | 4 | - | A History of Violence | $8,200,000 | - | - | - | 1,340 | $8,969,000 | - | 2 | New Line Cinema | - |
| 5 | 5 | - | Into the Blue | $7,000,000 | $7,057,854 | +$57,854 | +0.8% | 2,789 | $7,000,000 | $7,057,854 | 1 | Sony Pictures Releasing | - |
| 6 | 6 | - | Just Like Heaven | $6,100,000 | $6,128,180 | +$28,180 | +0.5% | 3,543 | $38,396,000 | $38,424,283 | 3 | DreamWorks Distribution | - |
| 7 | 7 | - | The Exorcism of Emily Rose | $4,400,000 | $4,380,280 | -$19,720 | -0.4% | 3,004 | $68,522,000 | $68,502,023 | 4 | Screen Gems | - |
| 8 | 8 | - | Roll Bounce | $4,025,000 | $4,029,257 | +$4,257 | +0.1% | 1,661 | $12,673,000 | $12,677,124 | 2 | Fox Searchlight Pictures | - |
| 9 | 9 | - | The Greatest Game Ever Played | $3,749,000 | $3,657,322 | -$91,678 | -2.4% | 1,014 | $3,749,000 | $3,657,322 | 1 | Walt Disney Studios Motion Pictures | - |
| 10 | 10 | - | The 40-Year-Old Virgin | $3,110,000 | $3,120,045 | +$10,045 | +0.3% | 2,152 | $101,396,000 | $101,405,778 | 7 | Universal Pictures | - |
| 11 | 11 | - | Lord of War | $2,450,000 | $2,462,153 | +$12,153 | +0.5% | 2,125 | $21,630,000 | $21,642,637 | 3 | Lionsgate | - |
| 12 | 12 | - | The Constant Gardener | $1,396,000 | - | - | - | 1,004 | $29,846,000 | - | 5 | Focus Features | - |
| 13 | 13 | - | Proof | $1,177,000 | - | - | - | 240 | $2,522,000 | - | 3 | Miramax | - |
| 14 | 16 | +2 | An Unfinished Life | $1,091,000 | - | - | - | 805 | $7,461,000 | - | 4 | Miramax | - |
| 15 | 14 | -1 | Transporter 2 | $1,075,000 | $1,160,986 | +$85,986 | +8% | 1,056 | $41,675,000 | $41,761,272 | 5 | Twentieth Century Fox | - |
| 16 | 15 | -1 | March of the Penguins | $1,068,000 | $1,114,959 | +$46,959 | +4.4% | 1,078 | $74,468,000 | $74,515,363 | 15 | Warner Independent Pictures (WIP) | - |
| 17 | 17 | - | Cry Wolf | $969,000 | - | - | - | 1,038 | $8,976,000 | - | 3 | Rogue Pictures | - |
| 18 | 18 | - | Oliver Twist | $875,000 | $888,721 | +$13,721 | +1.6% | 779 | $967,000 | $981,198 | 2 | Sony Pictures Releasing | - |
| 19 | 19 | - | Wedding Crashers | $625,000 | $590,352 | -$34,648 | -5.5% | 676 | $206,577,000 | $206,542,642 | 12 | New Line Cinema | - |
| 20 | 23 | +3 | Capote | $349,000 | $324,857 | -$24,143 | -6.9% | 12 | $349,000 | $324,857 | 1 | Sony Pictures Classics | - |
| 21 | 27 | +6 | Broken Flowers | $209,000 | $202,499 | -$6,501 | -3.1% | 222 | $13,230,000 | $13,224,003 | 9 | Focus Features | - |
| 22 | 30 | +8 | Everything Is Illuminated | $190,000 | $185,076 | -$4,924 | -2.6% | 60 | $462,000 | $457,646 | 3 | Warner Independent Pictures (WIP) | - |
| 23 | 35 | +12 | Thumbsucker | $176,000 | $156,250 | -$19,750 | -11.2% | 91 | $448,000 | $428,365 | 3 | Sony Pictures Classics | - |
| 24 | 34 | +10 | The Prize Winner of Defiance, Ohio | $155,000 | $159,056 | +$4,056 | +2.6% | 41 | $155,000 | $159,056 | 1 | DreamWorks Distribution | - |
| 25 | 36 | +11 | Junebug | $138,000 | $143,990 | +$5,990 | +4.3% | 125 | $2,262,000 | $2,267,595 | 9 | Sony Pictures Classics | - |
| 26 | 38 | +12 | Mirrormask | $127,000 | $126,449 | -$551 | -0.4% | 18 | $127,000 | $126,449 | 1 | IDP Distribution | - |
| 27 | 41 | +14 | The Thing About My Folks | $111,000 | $109,348 | -$1,652 | -1.5% | 113 | $712,000 | $710,031 | 3 | Picturehouse | - |
| 28 | 43 | +15 | Grizzly Man | $95,000 | $91,894 | -$3,106 | -3.3% | 81 | $2,661,000 | $2,657,856 | 8 | Lionsgate | - |
| 29 | 45 | +16 | G | $91,400 | $87,951 | -$3,449 | -3.8% | 40 | $554,000 | $550,693 | 3 | Aloha Releasing Inc. | - |
| 30 | 44 | +14 | The Man | $89,000 | $90,369 | +$1,369 | +1.5% | 234 | $8,277,000 | $8,278,660 | 4 | New Line Cinema | - |
| 31 | 46 | +15 | The Aristocrats | $84,000 | $82,426 | -$1,574 | -1.9% | 92 | $6,033,000 | $6,031,653 | 10 | THINKFilm | - |
| 32 | 51 | +19 | Separate Lies | $77,700 | $65,295 | -$12,405 | -16% | 25 | $141,000 | $128,792 | 3 | Fox Searchlight Pictures | - |
| 33 | 59 | +26 | Green Street Hooligans | $40,100 | $32,580 | -$7,520 | -18.8% | 21 | $243,000 | $235,722 | 4 | Freestyle Releasing | - |
| 34 | 56 | +22 | Little Manhattan | $38,200 | $36,397 | -$1,803 | -4.7% | 2 | $38,200 | $36,397 | 1 | Twentieth Century Fox | - |
| 35 | 54 | +19 | 2046 | $34,900 | $38,253 | +$3,353 | +9.6% | 47 | $1,304,000 | $1,306,948 | 9 | Sony Pictures Classics | - |
