| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Wedding Crashers | $197,508 | -28.5% | 58 | - | $3,405 | $1,025,014 | 3 | Roadshow Films | false | false |
| 2 | - | Kung Fu Hustle | $96,193 | - | 41 | - | $2,346 | $116,037 | 1 | Sony Pictures Releasing | true | false |
| 3 | - | Crash | $92,094 | - | 14 | - | $6,578 | $92,094 | 1 | Icon Film Distribution | true | false |
| 4 | 2 | The Skeleton Key | $67,666 | -37.6% | 42 | - | $1,611 | $211,010 | 2 | United International Pictures | false | false |
| 5 | 3 | Sin City | $63,881 | -41% | 51 | - | $1,252 | $490,699 | 3 | Buena Vista International | false | false |
| 6 | - | The Queen of Sheba's Pearls | $36,968 | - | 12 | - | $3,080 | $66,077 | 1 | Rialto Distribution | true | false |
| 7 | 4 | The Island | $36,768 | -26.1% | 48 | +1 | $766 | $925,590 | 6 | Warner Bros. | false | false |
| 8 | 5 | Beauty Shop | $21,017 | -45.6% | 18 | - | $1,167 | $69,632 | 2 | 20th Century Fox International | false | false |
| 9 | 8 | Ladies in Lavender | $19,617 | -18.9% | 28 | -3 | $700 | $1,101,534 | 13 | Icon Film Distribution | false | false |
| 10 | 6 | The Woodsman | $19,230 | -39.5% | 21 | +2 | $915 | $78,260 | 2 | Rialto Distribution | false | false |
| 11 | 7 | Fantastic Four | $19,203 | -29.5% | 42 | -9 | $457 | $1,773,358 | 8 | 20th Century Fox International | false | false |
| 12 | 13 | Madagascar | $18,517 | +1.5% | 58 | -5 | $319 | $3,494,167 | 10 | United International Pictures | false | false |
| 13 | 15 | Herbie Fully Loaded | $17,130 | +24.5% | 50 | +2 | $342 | $985,854 | 9 | Buena Vista International | false | false |
| 14 | 9 | Millions | $14,914 | -37.5% | 12 | - | $1,242 | $130,600 | 4 | 20th Century Fox International | false | false |
| 15 | 10 | The Longest Yard | $13,709 | -40.9% | 35 | -6 | $391 | $1,387,872 | 8 | Sony Pictures Releasing | false | false |
| 16 | 11 | A Good Woman | $13,328 | -30.6% | 17 | -7 | $784 | $501,302 | 9 | Hopscotch Films | false | false |
| 17 | 12 | War of the Worlds | $11,452 | -39.8% | 24 | -20 | $477 | $2,615,120 | 9 | United International Pictures | false | false |
| 18 | 16 | Mr. & Mrs. Smith | $8,474 | -27.9% | 22 | -4 | $385 | $2,518,950 | 12 | 20th Century Fox International | false | false |
| 19 | 14 | Land of the Dead | $6,321 | -59.7% | 12 | -14 | $526 | $173,158 | 4 | United International Pictures | false | false |
| 20 | 19 | What the #$*! Do We (K)now!? 2005 Re-release | $5,737 | -18.1% | 9 | -2 | $637 | $165,904 | 15 | Hopscotch Films | false | false |
