| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Charlie and the Chocolate Factory | $28,300,000 | $28,253,338 | -$46,662 | -0.2% | 3,790 | $114,100,000 | $114,058,892 | 2 | Warner Bros. | - |
| 2 | 2 | - | Wedding Crashers | $26,200,000 | - | - | - | 2,925 | $80,900,000 | - | 2 | New Line Cinema | - |
| 3 | 3 | - | Fantastic Four | $12,300,000 | $12,646,871 | +$346,871 | +2.8% | 3,449 | $122,600,000 | $122,931,780 | 3 | Twentieth Century Fox | - |
| 4 | 4 | - | The Island | $12,100,000 | $12,409,070 | +$309,070 | +2.6% | 3,122 | $12,100,000 | $12,409,070 | 1 | DreamWorks Distribution | - |
| 5 | 5 | - | Bad News Bears | $11,500,000 | $11,382,472 | -$117,528 | -1% | 3,183 | $11,500,000 | $11,382,472 | 1 | Paramount Pictures | - |
| 6 | 6 | - | War of the Worlds | $8,800,000 | $8,925,605 | +$125,605 | +1.4% | 3,265 | $208,300,000 | $208,421,643 | 4 | Paramount Pictures | - |
| 7 | 7 | - | Hustle & Flow | $8,100,000 | $8,017,808 | -$82,192 | -1% | 1,013 | $8,100,000 | $8,017,808 | 1 | Paramount Classics | - |
| 8 | 8 | - | The Devil's Rejects | $7,000,000 | $7,067,335 | +$67,335 | +1% | 1,757 | $7,000,000 | $7,067,335 | 1 | Lionsgate | - |
| 9 | 9 | - | Batman Begins | $4,700,000 | $4,727,469 | +$27,469 | +0.6% | 2,275 | $191,100,000 | $191,105,194 | 6 | Warner Bros. | - |
| 10 | 10 | - | March of the Penguins | $4,300,000 | $4,382,340 | +$82,340 | +1.9% | 695 | $9,200,000 | $9,306,689 | 5 | Warner Independent Pictures (WIP) | - |
| 11 | 11 | - | Mr. & Mrs. Smith | $3,600,000 | $3,701,842 | +$101,842 | +2.8% | 1,916 | $174,600,000 | $174,644,345 | 7 | Twentieth Century Fox | - |
| 12 | 12 | - | Herbie: Fully Loaded | $1,900,000 | $2,020,307 | +$120,307 | +6.3% | 1,953 | $60,200,000 | $60,327,540 | 5 | Walt Disney Studios Motion Pictures | - |
| 13 | 20 | +7 | Me and You and Everyone We Know | $340,728 | - | - | - | 136 | $1,924,460 | - | 6 | IFC Films | - |
