| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Fantastic Four | $1,686,430 | -39.5% | - | - | - | $5,759,854 | 2 | 20th Century Fox International | false | false |
| 2 | 3 | War of the Worlds | $1,492,741 | -43.3% | - | - | - | $12,972,259 | 3 | United International Pictures | false | false |
| 3 | - | Sin City | $1,451,231 | - | - | - | - | $1,457,497 | 1 | Buena Vista International | true | false |
| 4 | 2 | Bewitched | $1,420,495 | -46.3% | - | - | - | $5,222,250 | 2 | Sony Pictures Releasing | false | false |
| 5 | 4 | Madagascar | $794,981 | -45.6% | - | - | - | $18,013,618 | 5 | United International Pictures | false | false |
| 6 | 5 | Herbie Fully Loaded | $638,522 | -29.3% | - | - | - | $6,418,842 | 4 | Buena Vista International | false | false |
| 7 | - | House of Wax | $580,585 | - | - | - | - | $580,585 | 1 | Roadshow Films | true | false |
| 8 | 6 | Batman Begins | $514,643 | -37.2% | - | - | - | $10,842,163 | 5 | Warner Bros. | false | false |
| 9 | 7 | Mr. & Mrs. Smith | $305,372 | -40.6% | - | - | - | $14,653,628 | 6 | 20th Century Fox International | false | false |
| 10 | 8 | Pooh's Heffalump Movie | $188,296 | -27.5% | - | - | - | $1,336,173 | 4 | Buena Vista International | false | false |
| 11 | 12 | Oyster Farmer | $148,856 | -5.7% | - | - | - | $559,545 | 3 | Dendy Films | false | false |
| 12 | 10 | A Good Woman | $144,899 | -15% | - | - | - | $1,263,553 | 4 | Hopscotch Films | false | false |
| 13 | 9 | The Sisterhood of the Traveling Pants | $120,932 | -36.9% | - | - | - | $1,234,030 | 4 | Warner Bros. | false | false |
| 14 | 11 | Star Wars: Episode III - Revenge of the Sith | $85,815 | -46.5% | - | - | - | $26,270,330 | 9 | 20th Century Fox International | false | false |
| 15 | 13 | The Longest Yard | $55,722 | -51.6% | - | - | - | $8,109,838 | 7 | Sony Pictures Releasing | false | false |
| 16 | 16 | Sharks 3D | $43,135 | -3.4% | - | - | - | $467,519 | 11 | IMAX | false | false |
| 17 | - | Because of Winn-Dixie | $36,676 | - | - | - | - | $36,676 | 1 | 20th Century Fox International | true | false |
| 18 | 15 | My Summer of Love | $30,337 | -32.6% | - | - | - | $188,048 | 3 | United International Pictures | false | false |
| 19 | 17 | The Yes Men | $23,739 | -22.6% | - | - | - | $75,257 | 2 | Rialto Distribution | false | false |
| 20 | 18 | The Beat That My Heart Skipped | $23,001 | -21.6% | - | - | - | $117,098 | 3 | Palace Films | false | false |
