| Est. Rank | Rank | Diff | Release
| Est. Gross | Actual | Diff | % Diff | Theaters | Estimated Total | Actual | Weekend | Distributor
| New This Week
|
|---|
| 1 | 1 | - | Batman Begins | $46,900,000 | $48,745,440 | +$1,845,440 | +3.9% | 3,858 | $71,100,000 | $72,896,986 | 1 | Warner Bros. | - |
| 2 | 2 | - | Mr. & Mrs. Smith | $27,300,000 | $26,037,023 | -$1,262,977 | -4.6% | 3,451 | $98,000,000 | $96,697,986 | 2 | Twentieth Century Fox | - |
| 3 | 3 | - | Madagascar | $11,100,000 | $10,737,325 | -$362,675 | -3.3% | 3,533 | $147,200,000 | $146,831,846 | 4 | DreamWorks Distribution | - |
| 4 | 4 | - | Star Wars: Episode III - Revenge of the Sith | $9,700,000 | $10,038,498 | +$338,498 | +3.5% | 2,923 | $347,800,000 | $348,140,685 | 5 | Twentieth Century Fox | - |
| 5 | 5 | - | The Longest Yard | $8,000,000 | $8,239,853 | +$239,853 | +3% | 3,312 | $131,900,000 | $132,144,471 | 4 | Paramount Pictures | - |
| 6 | 6 | - | The Adventures of Sharkboy and Lavagirl 3-D | $6,600,000 | - | - | - | 2,655 | $24,000,000 | - | 2 | Dimension Films | - |
| 7 | 8 | +1 | The Perfect Man | $5,500,000 | $5,300,980 | -$199,020 | -3.6% | 2,087 | $5,500,000 | $5,300,980 | 1 | Universal Pictures | - |
| 8 | 7 | -1 | Cinderella Man | $5,200,000 | $5,572,285 | +$372,285 | +7.2% | 2,610 | $43,600,000 | $43,893,695 | 3 | Universal Pictures | - |
| 9 | 9 | - | The Sisterhood of the Traveling Pants | $3,200,000 | $3,127,232 | -$72,768 | -2.3% | 2,206 | $30,200,000 | $30,160,110 | 3 | Warner Bros. | - |
| 10 | 10 | - | The Honeymooners | $2,600,000 | $2,648,330 | +$48,330 | +1.9% | 1,912 | $9,500,000 | $9,551,584 | 2 | Paramount Pictures | - |
| 11 | 11 | - | Crash | $1,300,000 | $1,297,689 | -$2,311 | -0.2% | 651 | $46,400,000 | $46,422,459 | 7 | Lionsgate | - |
| 12 | 12 | - | Monster-in-Law | $1,100,000 | - | - | - | 1,165 | $78,700,000 | - | 6 | New Line Cinema | - |
