| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Mr. & Mrs. Smith | $7,150,617 | - | 450 | - | $15,890 | $7,150,617 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Star Wars: Episode III - Revenge of the Sith | $2,898,988 | -51.8% | 489 | -1 | $5,928 | $64,223,442 | 4 | 20th Century Fox International | false | false |
| 3 | 2 | Sin City | $1,863,736 | -58.2% | 399 | +4 | $4,671 | $8,433,499 | 2 | Buena Vista International | false | false |
| 4 | 3 | The Pacifier | $699,456 | -53.8% | 333 | -18 | $2,100 | $6,139,236 | 3 | Buena Vista International | false | false |
| 5 | 6 | House of Wax | $458,831 | -53.2% | 294 | -10 | $1,560 | $4,590,946 | 3 | Warner Bros. | false | false |
| 6 | 5 | Monster-in-Law | $435,363 | -56.2% | 318 | -46 | $1,369 | $10,710,495 | 5 | Entertainment Film Distributors | false | false |
| 7 | 4 | The League of Gentlemen's Apocalypse | $425,203 | -57.9% | 278 | -4 | $1,529 | $1,871,417 | 2 | United International Pictures | false | false |
| 8 | 7 | Millions | $216,856 | -57.7% | 237 | -18 | $915 | $2,265,203 | 3 | Pathé | false | false |
| 9 | - | Parineeta | $209,048 | - | 33 | - | $6,334 | $209,048 | 1 | UTV Motion Pictures | true | false |
| 10 | 8 | Kingdom of Heaven | $112,796 | -64.5% | 125 | -82 | $902 | $13,823,818 | 6 | 20th Century Fox International | false | false |
| 11 | 11 | Bunty Aur Babli | $90,368 | -48.1% | 28 | -2 | $3,227 | $858,241 | 3 | Yash Raj Films | false | false |
| 12 | 9 | The Hitchhiker's Guide to the Galaxy | $86,230 | -64.2% | 121 | -101 | $712 | $19,154,624 | 7 | Buena Vista International | false | false |
| 13 | 13 | The Consequences of Love | $53,161 | -40.1% | 9 | -1 | $5,906 | $365,419 | 3 | Artificial Eye | false | false |
| 14 | 12 | Valiant | $47,579 | -67.8% | 196 | -100 | $242 | $15,287,905 | 12 | Entertainment Film Distributors | false | false |
| 15 | 10 | It's All Gone Pete Tong | $38,540 | -83.8% | 77 | -167 | $500 | $1,347,044 | 3 | Redbus Film Distribution | false | false |
| 16 | 15 | A Good Woman | $26,394 | -56.8% | 38 | -5 | $694 | $1,049,886 | 5 | Vertigo Films | false | false |
| 17 | 17 | Mysterious Skin | $21,185 | -32.5% | 14 | - | $1,513 | $293,982 | 4 | Tartan | false | false |
| 18 | 16 | The Interpreter | $19,448 | -68.1% | 28 | -22 | $694 | $12,965,074 | 9 | United International Pictures | false | false |
| 19 | - | Inside Deep Throat | $17,952 | - | 18 | - | $997 | $17,952 | 1 | Momentum Pictures | true | false |
