| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Hitch | $3,097,914 | -28% | 449 | - | $6,899 | $20,833,004 | 4 | Sony Pictures Releasing | false | false |
| 2 | 1 | Robots | $2,757,631 | -45.1% | 487 | +13 | $5,662 | $9,721,097 | 2 | 20th Century Fox International | false | false |
| 3 | - | Miss Congeniality 2: Armed & Fabulous | $2,429,416 | - | 380 | - | $6,393 | $2,429,416 | 1 | Warner Bros. | true | false |
| 4 | 3 | Constantine | $2,424,987 | -39.7% | 352 | -1 | $6,889 | $8,178,095 | 2 | Warner Bros. | false | false |
| 5 | - | Valiant | $2,045,543 | - | 403 | - | $5,075 | $2,045,543 | 1 | Entertainment Film Distributors | true | false |
| 6 | 4 | Hostage | $858,596 | -21.3% | 310 | -18 | $2,769 | $5,172,612 | 3 | Entertainment Film Distributors | false | false |
| 7 | 5 | Pooh's Heffalump Movie | $354,303 | +16.7% | 409 | +10 | $866 | $883,560 | 2 | Buena Vista International | false | false |
| 8 | - | Melinda and Melinda | $241,169 | - | 53 | - | $4,550 | $241,169 | 1 | 20th Century Fox International | true | false |
| 9 | 7 | Meet the Fockers | $197,184 | -28.8% | 143 | -65 | $1,378 | $53,045,518 | 9 | United International Pictures | false | false |
| 10 | - | Maria Full of Grace | $157,353 | - | 24 | - | $6,556 | $157,353 | 1 | Icon Film Distribution | true | false |
| 11 | 6 | Boogeyman | $154,832 | -47.8% | 171 | -81 | $905 | $3,882,799 | 4 | United International Pictures | false | false |
| 12 | 10 | The Chorus 2005 Re-release | $149,160 | -17.1% | 64 | -2 | $2,330 | $954,638 | 3 | Pathé | false | false |
| 13 | 11 | Are We There Yet? | $138,535 | -22.7% | 191 | -17 | $725 | $5,075,431 | 6 | Sony Pictures Releasing | false | false |
| 14 | 12 | Million Dollar Baby | $136,068 | -20.5% | 89 | -24 | $1,528 | $9,623,435 | 11 | Entertainment Film Distributors | false | false |
| 15 | 8 | Hotel Rwanda | $131,234 | -34.7% | 88 | -31 | $1,491 | $2,494,778 | 5 | Entertainment Film Distributors | false | false |
| 16 | 17 | Sideways | $104,999 | -8% | 56 | -5 | $1,874 | $6,458,922 | 9 | 20th Century Fox International | false | false |
| 17 | 15 | Five Times Two | $92,634 | -33.4% | 17 | +1 | $5,449 | $355,079 | 2 | UGC Distribution | false | false |
| 18 | 16 | Coach Carter | $92,270 | -26.8% | 63 | -19 | $1,464 | $2,772,936 | 5 | United International Pictures | false | false |
| 19 | - | Mickybo and Me | $89,406 | - | 28 | - | $3,193 | $89,406 | 1 | - | true | false |
| 20 | 18 | The Machinist | $82,096 | -19.5% | 26 | +1 | $3,157 | $314,913 | 2 | Tartan | false | false |
