| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Hitch | $1,846,637 | -33.1% | - | - | - | $5,516,240 | 2 | Sony Pictures Releasing | false | false |
| 2 | - | Be Cool | $960,330 | - | - | - | - | $976,522 | 1 | 20th Century Fox International | true | false |
| 3 | 2 | Constantine | $535,289 | -47.9% | - | - | - | $4,869,443 | 3 | Roadshow Films | false | false |
| 4 | - | Are We There Yet? | $529,805 | - | - | - | - | $545,828 | 1 | Sony Pictures Releasing | true | false |
| 5 | 4 | Million Dollar Baby | $386,815 | -28.2% | - | - | - | $4,412,795 | 6 | Roadshow Films | false | false |
| 6 | 3 | The Aviator | $368,989 | -41.9% | - | - | - | $5,891,639 | 5 | Roadshow Films | false | false |
| 7 | 5 | Bride & Prejudice | $215,287 | -38.4% | - | - | - | $2,510,932 | 4 | Roadshow Films | false | false |
| 8 | - | Friday Night Lights | $170,089 | - | - | - | - | $170,610 | 1 | United International Pictures | true | false |
| 9 | 7 | Sideways | $127,223 | -33.1% | - | - | - | $3,137,183 | 7 | 20th Century Fox International | false | false |
| 10 | 11 | My House in Umbria | $107,874 | -3.1% | - | - | - | $482,235 | 3 | Hopscotch Films | false | false |
| 11 | 8 | House of Flying Daggers | $99,330 | -45.6% | - | - | - | $1,759,225 | 4 | United International Pictures | false | false |
| 12 | - | Ong-Bak: The Thai Warrior | $87,158 | - | - | - | - | $87,158 | 1 | Madman Entertainment | true | false |
| 13 | 10 | Meet the Fockers | $82,704 | -34.8% | - | - | - | $27,625,667 | 12 | United International Pictures | false | false |
| 14 | 12 | Hotel Rwanda | $80,849 | -24.6% | - | - | - | $468,318 | 3 | Roadshow Films | false | false |
| 15 | 6 | Spanglish | $69,313 | -66.1% | - | - | - | $2,113,280 | 4 | Sony Pictures Releasing | false | false |
| 16 | 9 | Hide and Seek | $63,362 | -63.8% | - | - | - | $3,505,659 | 5 | 20th Century Fox International | false | false |
| 17 | 14 | The Door in the Floor | $60,628 | -30.3% | - | - | - | $171,278 | 2 | Dendy Films | false | false |
| 18 | 17 | The Motorcycle Diaries | $59,479 | +47.8% | - | - | - | $2,474,723 | 13 | Dendy Films | false | false |
| 19 | 13 | Ray | $46,218 | -52.7% | - | - | - | $3,111,367 | 7 | United International Pictures | false | false |
| 20 | - | Riding Giants | $41,610 | - | - | - | - | $41,610 | 1 | Sony Pictures Releasing | true | false |
