| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Million Dollar Baby | $106,786 | -11.7% | 40 | +3 | $2,669 | $877,581 | 5 | Distribution Company | false | false |
| 2 | 3 | The Grudge | $103,523 | -13.1% | 38 | - | $2,724 | $344,480 | 2 | Distribution Company | false | false |
| 3 | 2 | The Aviator | $97,565 | -19.2% | 62 | +6 | $1,573 | $627,490 | 3 | Warner Bros. | false | false |
| 4 | 4 | Meet the Fockers | $94,892 | +9.2% | 84 | +7 | $1,129 | $3,074,958 | 9 | United International Pictures | false | false |
| 5 | - | Open Water | $75,082 | - | 23 | - | $3,264 | $75,082 | 1 | CDI Films | true | false |
| 6 | 5 | Alexander | $64,943 | -4% | 54 | +9 | $1,202 | $770,720 | 5 | Warner Bros. | false | false |
| 7 | 6 | Hide and Seek | $52,174 | -3.3% | 57 | +8 | $915 | $1,111,846 | 7 | 20th Century Fox International | false | false |
| 8 | - | Vera Drake | $49,999 | - | 19 | - | $2,631 | $49,999 | 1 | Alfa Films | true | false |
| 9 | 7 | Finding Neverland | $43,176 | -11.4% | 48 | +3 | $899 | $738,359 | 6 | Buena Vista International | false | false |
| 10 | 8 | Sideways | $39,039 | -0.1% | 10 | -1 | $3,903 | $285,176 | 4 | 20th Century Fox International | false | false |
| 11 | - | Spanglish | $30,857 | - | 13 | - | $2,373 | $30,857 | 1 | Sony Pictures Releasing | true | false |
| 12 | 9 | The Chorus 2005 Re-release | $30,636 | -3% | 12 | - | $2,553 | $109,382 | 2 | Buena Vista International | false | false |
| 13 | 11 | Whisky | $23,556 | -13.9% | 13 | - | $1,812 | $82,024 | 2 | Primer Plano Film Group | false | false |
| 14 | 13 | National Treasure | $21,740 | +2.6% | 55 | +5 | $395 | $969,579 | 8 | Buena Vista International | false | false |
| 15 | 14 | The SpongeBob SquarePants Movie | $19,985 | -2% | 63 | -5 | $317 | $1,156,162 | 10 | United International Pictures | false | false |
| 16 | 10 | Closer | $19,432 | -32.3% | 34 | - | $571 | $627,492 | 7 | Sony Pictures Releasing | false | false |
| 17 | 12 | The Sea Inside | $16,504 | -24.3% | 25 | - | $660 | $243,592 | 6 | 20th Century Fox International | false | false |
| 18 | 15 | A Series of Unfortunate Events | $16,031 | -19% | 34 | -10 | $471 | $456,324 | 6 | United International Pictures | false | false |
| 19 | - | Elektra | $12,986 | - | 20 | - | $649 | $85,604 | 4 | 20th Century Fox International | false | false |
