| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Home Alone | - | - | - | $81,365,353 | 2,173 | $285,761,243 | Nov 16 | Twentieth Century Fox | false |
| 2 | Dances with Wolves | - | - | - | $54,840,247 | 1,636 | $184,208,848 | Nov 9 | Orion Pictures | false |
| 3 | Sleeping with the Enemy | - | - | - | $45,376,689 | 1,545 | $101,599,005 | Feb 8 | Twentieth Century Fox | false |
| 4 | Kindergarten Cop | - | - | - | $44,446,660 | 1,937 | $91,457,688 | Dec 22 | Universal Pictures | false |
| 5 | Awakenings | - | - | - | $41,730,573 | 1,330 | $52,096,475 | Dec 22 | Columbia Pictures | false |
| 6 | The Silence of the Lambs | - | - | - | $36,250,654 | 1,642 | $130,742,922 | Feb 14 | Orion Pictures | false |
| 7 | Edward Scissorhands | - | - | - | $27,677,187 | 1,372 | $56,362,352 | Dec 7 | Twentieth Century Fox | false |
| 8 | The Godfather Part III | - | - | - | $27,632,696 | 1,922 | $66,666,062 | Dec 25 | Paramount Pictures | false |
| 9 | White Fang | - | - | - | $27,587,820 | 1,259 | $34,793,160 | Jan 18 | Walt Disney Studios Motion Pictures | false |
| 10 | Lionheart | - | - | - | $24,078,196 | 1,485 | $24,078,196 | Jan 11 | Universal Pictures | false |
| 11 | Green Card | - | - | - | $23,824,005 | 757 | $29,888,235 | Dec 25 | Walt Disney Studios Motion Pictures | false |
| 12 | Hamlet | - | - | - | $20,254,479 | 624 | $20,710,451 | Dec 22 | Warner Bros. | false |
| 13 | Misery | - | - | - | $20,249,150 | 1,370 | $61,276,872 | Nov 30 | Columbia Pictures | false |
| 14 | Look Who's Talking Too | - | - | - | $18,447,138 | 1,647 | $47,789,074 | Dec 14 | TriStar Pictures | false |
| 15 | L.A. Story | - | - | - | $18,297,177 | 1,122 | $28,862,081 | Feb 8 | TriStar Pictures | false |
| 16 | Mermaids | - | - | - | $17,892,119 | 1,154 | $35,419,397 | Dec 14 | Orion Pictures | false |
| 17 | Three Men and a Little Lady | - | - | - | $16,428,227 | 1,614 | $71,609,321 | Nov 21 | Walt Disney Studios Motion Pictures | false |
| 18 | King Ralph | - | - | - | $15,668,505 | 1,646 | $34,002,045 | Feb 15 | Universal Pictures | false |
| 19 | Once Around | - | - | - | $14,851,083 | 735 | $14,851,083 | Jan 18 | Universal Pictures | false |
| 20 | Not Without My Daughter | - | - | - | $14,789,113 | 1,141 | $14,789,113 | Jan 11 | Metro-Goldwyn-Mayer (MGM) | false |
| 21 | Flight of the Intruder | - | - | - | $14,587,732 | 1,489 | $14,587,732 | Jan 18 | Paramount Pictures | false |
| 22 | The Grifters | - | - | - | $13,273,636 | 780 | $13,446,769 | Dec 7 | Miramax | false |
| 23 | The NeverEnding Story II: The Next Chapter | - | - | - | $12,923,619 | 1,208 | $17,373,527 | Feb 8 | Warner Bros. | false |
| 24 | The Russia House | - | - | - | $10,588,133 | 768 | $22,997,992 | Dec 22 | Metro-Goldwyn-Mayer (MGM) | false |
| 25 | Warlock | - | - | - | $9,094,451 | 261 | $9,094,451 | Jan 11 | Trimark Pictures | false |
| 26 | Ghost | - | - | - | $7,064,201 | 1,766 | $217,631,306 | Jul 13 | Paramount Pictures | false |
| 27 | Alice | - | - | - | $7,008,891 | 325 | $7,331,647 | Dec 25 | Orion Pictures | false |
| 28 | Nothing But Trouble | - | - | - | $6,893,080 | 1,671 | $8,479,793 | Feb 15 | Warner Bros. | false |
| 29 | The Rescuers Down Under | - | - | - | $5,601,121 | 1,487 | $27,931,461 | Nov 16 | Walt Disney Studios Motion Pictures | false |
| 30 | Eve of Destruction | - | - | - | $5,451,119 | 987 | $5,451,119 | Jan 18 | Orion Pictures | false |
| 31 | Scenes from a Mall | - | - | - | $4,831,703 | 1,039 | $9,563,393 | Feb 22 | Walt Disney Studios Motion Pictures | false |
| 32 | Run | - | - | - | $4,409,328 | 1,175 | $4,409,328 | Feb 1 | Walt Disney Studios Motion Pictures | false |
| 33 | Popcorn | - | - | - | $4,205,000 | 1,055 | $4,205,000 | Feb 1 | - | false |
| 34 | The Bonfire of the Vanities | - | - | - | $4,196,224 | 1,395 | $15,691,192 | Dec 22 | Warner Bros. | false |
| 35 | He Said, She Said | - | - | - | $3,645,415 | 908 | $9,804,775 | Feb 22 | Paramount Pictures | false |
| 36 | The Rookie | - | - | - | $3,327,792 | 1,862 | $21,633,874 | Dec 7 | Warner Bros. | false |
| 37 | Vincent & Theo | - | - | - | $2,195,027 | 59 | $2,231,274 | Nov 2 | Hemdale | false |
| 38 | Cadence | - | - | - | $2,070,871 | 31 | $2,070,871 | Jan 18 | New Line Cinema | false |
| 39 | Almost an Angel | - | - | - | $1,814,586 | 1,373 | $6,939,946 | Dec 22 | Paramount Pictures | false |
| 40 | Havana | - | - | - | $1,800,036 | 835 | $9,243,140 | Dec 14 | Universal Pictures | false |
| 41 | The Sheltering Sky | - | - | - | $1,660,882 | 95 | $2,075,084 | Dec 14 | Warner Bros. | false |
| 42 | Book of Love | - | - | - | $1,382,259 | 227 | $1,382,259 | Feb 1 | New Line Cinema | false |
| 43 | Goodfellas | - | - | - | $1,214,337 | 1,328 | $46,836,214 | Sep 19 | Warner Bros. | false |
| 44 | Hidden Agenda | - | - | - | $944,212 | 114 | $1,030,938 | Nov 21 | Hemdale | false |
| 45 | Come See the Paradise | - | - | - | $725,020 | 97 | $947,306 | Dec 25 | Twentieth Century Fox | false |
| 46 | Queens Logic | - | - | - | $612,781 | 37 | $612,781 | Feb 1 | New Line Cinema | false |
| 47 | Meet the Applegates | - | - | - | $485,772 | 155 | $485,772 | Feb 1 | Triton Pictures | false |
| 48 | Men of Respect | - | - | - | $139,155 | 33 | $139,155 | Jan 18 | Columbia Pictures | false |
| 49 | Rosencrantz & Guildenstern Are Dead | - | - | - | $33,818 | 18 | $739,104 | Feb 8 | Cinecom Pictures | false |
| 50 | Iron & Silk | - | - | - | $18,312 | 14 | $356,077 | Feb 15 | Miramax | false |
