| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Rain Man | - | - | - | $71,912,605 | 1,590 | $172,825,435 | Dec 16 | Metro-Goldwyn-Mayer (MGM) | false |
| 2 | Twins | - | - | - | $42,409,110 | 1,659 | $111,938,388 | Dec 9 | Universal Pictures | false |
| 3 | Beaches | - | - | - | $38,933,963 | 1,122 | $57,041,866 | Dec 23 | Walt Disney Studios Motion Pictures | false |
| 4 | Working Girl | - | - | - | $32,449,802 | 1,149 | $63,779,477 | Dec 23 | Twentieth Century Fox | false |
| 5 | The Accidental Tourist | - | - | - | $32,193,259 | 954 | $32,632,093 | Dec 23 | Warner Bros. | false |
| 6 | Three Fugitives | - | - | - | $30,365,895 | 1,374 | $40,586,886 | Jan 27 | Walt Disney Studios Motion Pictures | false |
| 7 | The Naked Gun: From the Files of Police Squad! | - | - | - | $29,267,165 | 1,969 | $78,756,177 | Dec 2 | Paramount Pictures | false |
| 8 | Mississippi Burning | - | - | - | $25,066,394 | 1,134 | $34,603,943 | Dec 9 | Orion Pictures | false |
| 9 | The 'Burbs | - | - | - | $20,231,142 | 1,956 | $36,601,993 | Feb 17 | Universal Pictures | false |
| 10 | Dirty Rotten Scoundrels | - | - | - | $18,517,567 | 1,515 | $42,039,085 | Dec 16 | Orion Pictures | false |
| 11 | The Fly II | - | - | - | $16,114,305 | 1,528 | $20,021,322 | Feb 10 | Twentieth Century Fox | false |
| 12 | Dangerous Liaisons | - | - | - | $15,867,583 | 762 | $34,670,720 | Dec 23 | Warner Bros. | false |
| 13 | Her Alibi | - | - | - | $15,190,711 | 1,429 | $18,699,037 | Feb 3 | Warner Bros. | false |
| 14 | Bill & Ted's Excellent Adventure | - | - | - | $12,978,843 | 1,321 | $40,485,039 | Feb 17 | Orion Pictures | false |
| 15 | Oliver & Company | - | - | - | $12,279,408 | 1,503 | $53,279,055 | Nov 18 | Walt Disney Studios Motion Pictures | false |
| 16 | Tequila Sunrise | - | - | - | $11,613,929 | 1,411 | $41,292,551 | Dec 2 | Warner Bros. | false |
| 17 | Cousins | - | - | - | $11,327,358 | 747 | $22,026,369 | Feb 10 | Paramount Pictures | false |
| 18 | Who's Harry Crumb? | - | - | - | $10,982,364 | 1,198 | $10,982,364 | Feb 3 | TriStar Pictures | false |
| 19 | I'm Gonna Git You Sucka | - | - | - | $10,486,927 | 266 | $13,030,057 | Dec 16 | United Artists | false |
| 20 | The Land Before Time | - | - | - | $9,680,361 | 1,414 | $48,336,291 | Nov 18 | Universal Pictures | false |
| 21 | DeepStar Six | - | - | - | $8,143,225 | 1,118 | $8,143,225 | Jan 13 | TriStar Pictures | false |
| 22 | Tap | - | - | - | $6,944,971 | 587 | $9,114,702 | Feb 10 | TriStar Pictures | false |
| 23 | True Believer | - | - | - | $5,953,979 | 897 | $8,742,750 | Feb 17 | Columbia Pictures | false |
| 24 | Scrooged | - | - | - | $4,857,740 | 1,897 | $60,328,558 | Nov 23 | Paramount Pictures | false |
| 25 | My Stepmother Is an Alien | - | - | - | $4,823,344 | 1,148 | $13,854,000 | Dec 9 | Columbia Pictures | false |
| 26 | Torch Song Trilogy | - | - | - | $4,733,264 | 135 | $4,865,997 | Dec 16 | New Line Cinema | false |
| 27 | The January Man | - | - | - | $4,611,062 | 883 | $4,611,062 | Jan 13 | Metro-Goldwyn-Mayer (MGM) | false |
| 28 | The Mighty Quinn | - | - | - | $4,557,214 | 234 | $4,557,214 | Feb 17 | Metro-Goldwyn-Mayer (MGM) | false |
| 29 | Hellbound: Hellraiser II | - | - | - | $4,051,754 | 1,187 | $12,090,735 | Dec 23 | New World Pictures | false |
| 30 | Physical Evidence | - | - | - | $3,560,932 | 695 | $3,560,932 | Jan 27 | Columbia Pictures | false |
| 31 | Kinjite: Forbidden Subjects | - | - | - | $3,416,846 | 320 | $3,416,846 | Feb 3 | Cannon Film Distributors | false |
| 32 | Talk Radio | - | - | - | $3,138,568 | 653 | $3,468,572 | Dec 23 | Universal Pictures | false |
| 33 | Cocoon: The Return | - | - | - | $2,845,102 | 997 | $18,924,919 | Nov 23 | Twentieth Century Fox | false |
| 34 | Gleaming the Cube | - | - | - | $2,777,280 | 469 | $2,777,280 | Jan 13 | Twentieth Century Fox | false |
| 35 | Bird | - | - | - | $2,138,486 | 93 | $2,181,286 | Sep 30 | Warner Bros. | false |
| 36 | Vincent | - | - | - | $1,569,634 | 16 | $1,577,480 | Aug 19 | Roxie Releasing | false |
| 37 | Another Woman | - | - | - | $1,446,787 | 24 | $1,562,749 | Oct 14 | Orion Pictures | false |
| 38 | Pumpkinhead 1989 Re-release | - | - | - | $1,000,000 | 142 | $1,000,000 | Jan 13 | United Artists | false |
| 39 | American Ninja 3: Blood Hunt | - | - | - | $902,152 | 140 | $902,152 | Feb 24 | Cannon Film Distributors | false |
| 40 | Parents | - | - | - | $870,532 | 94 | $870,532 | Jan 27 | Vestron Pictures | false |
| 41 | The Toxic Avenger Part II | - | - | - | $792,966 | 15 | $792,966 | Feb 24 | Troma | false |
| 42 | Ernest Saves Christmas | - | - | - | $386,375 | 1,640 | $28,202,109 | Nov 11 | Walt Disney Studios Motion Pictures | false |
| 43 | The Chocolate War | - | - | - | $289,273 | 11 | $303,624 | Nov 18 | - | false |
| 44 | Some Girls | - | - | - | $259,352 | 23 | $401,421 | Sep 9 | Metro-Goldwyn-Mayer (MGM) | false |
| 45 | The Experts | - | - | - | $249,281 | 100 | $169,203 | Jan 13 | Paramount Pictures | false |
| 46 | Manifesto | - | - | - | $70,060 | 1 | $70,060 | Jan 27 | Cannon Film Distributors | false |
| 47 | Cohen and Tate | - | - | - | $64,227 | 75 | $64,227 | Jan 27 | Hemdale | false |
| 48 | Rachel River | - | - | - | $60,698 | 4 | $60,698 | Jan 20 | Taurus Entertainment Company | false |
| 49 | Bert Rigby, You're a Fool | - | - | - | $60,659 | 23 | $75,868 | Feb 24 | Warner Bros. | false |
| 50 | High Hopes | - | - | - | $41,947 | 25 | $1,192,322 | Feb 24 | Skouras Pictures | false |
| 51 | Powwow Highway | - | - | - | $14,523 | 14 | $283,747 | Feb 24 | Warner Bros. | false |
| 52 | Under the Sun of Satan | - | - | - | $12,184 | 2 | $68,765 | Jan 20 | Alive Films | false |
| 53 | Paperhouse | - | - | - | $8,540 | 9 | $241,278 | Feb 17 | Vestron Pictures | false |
