| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Doctor Strange in the Multiverse of Madness | - | - | - | $247,993,449 | 4,534 | $411,331,607 | 60.3% | May 6, 2022 | Walt Disney Studios Motion Pictures |
| 2 | The Bad Guys | - | - | - | $13,276,485 | 4,042 | $97,459,240 | 13.6% | Apr 22, 2022 | Universal Pictures |
| 3 | Sonic the Hedgehog 2 | - | - | - | $8,489,996 | 4,258 | $190,872,904 | 4.4% | Apr 8, 2022 | Paramount Pictures |
| 4 | Everything Everywhere All at Once | - | - | - | $6,476,102 | 2,220 | $77,191,785 | 8.4% | Mar 25, 2022 | A24 |
| 5 | Fantastic Beasts: The Secrets of Dumbledore | - | - | - | $6,222,960 | 4,245 | $95,850,844 | 6.5% | Apr 15, 2022 | Warner Bros. |
| 6 | The Northman | - | - | - | $4,673,490 | 3,284 | $34,233,110 | 13.7% | Apr 22, 2022 | Focus Features |
| 7 | The Lost City | - | - | - | $4,002,710 | 4,283 | $105,344,029 | 3.8% | Mar 25, 2022 | Paramount Pictures |
| 8 | The Unbearable Weight of Massive Talent | - | - | - | $2,598,211 | 3,036 | $20,300,157 | 12.8% | Apr 22, 2022 | Lionsgate |
| 9 | Memory | - | - | - | $2,131,828 | 2,555 | $7,329,043 | 29.1% | Apr 29, 2022 | Open Road Films (II) |
| 10 | Firestarter | - | - | - | $1,549,840 | 3,413 | $9,739,250 | 15.9% | May 13, 2022 | Universal Pictures |
| 11 | Father Stu | - | - | - | $1,300,498 | 2,705 | $20,884,796 | 6.2% | Apr 13, 2022 | Sony Pictures Releasing |
| 12 | Morbius | - | - | - | $881,398 | 4,268 | $73,865,530 | 1.2% | Apr 1, 2022 | Columbia Pictures |
| 13 | The Duke | - | - | - | $595,197 | 353 | $1,526,970 | 39% | Apr 22, 2022 | Sony Pictures Classics |
| 14 | Family Camp | - | - | - | $498,578 | 1,057 | $3,973,263 | 12.5% | May 13, 2022 | Roadside Attractions |
| 15 | Ambulance | - | - | - | $459,855 | 3,412 | $22,781,115 | 2% | Apr 8, 2022 | Universal Pictures |
| 16 | Petite Maman | - | - | - | $344,781 | 224 | $829,065 | 41.6% | Apr 22, 2022 | Neon |
| 17 | Uncharted | - | - | - | $299,449 | 4,275 | $148,648,820 | 0.2% | Feb 18, 2022 | Sony Pictures Releasing |
| 18 | The Batman | - | - | - | $140,876 | 4,417 | $369,345,583 | <0.1% | Mar 4, 2022 | Warner Bros. |
| 19 | ¿Y cómo es él? | - | - | - | $117,874 | 325 | $1,500,636 | 7.9% | Apr 22, 2022 | Lionsgate |
| 20 | Spider-Man: No Way Home | - | - | - | $64,847 | 4,336 | $804,793,477 | <0.1% | Dec 17, 2021 | Sony Pictures Releasing |
| 21 | Happening | - | - | - | $63,219 | 188 | $181,023 | 34.9% | May 6, 2022 | IFC Films |
| 22 | Inland Empire 2022 Re-release | - | - | - | $54,885 | 14 | $253,523 | 21.6% | Apr 8, 2022 | Janus Films |
| 23 | Vortex | - | - | - | $49,359 | 39 | $145,708 | 33.9% | May 6, 2022 | Utopia |
| 24 | Eiffel | - | - | - | $43,803 | 308 | $444,814 | 9.8% | Apr 29, 2022 | Blue Fox Entertainment |
| 25 | Jujutsu Kaisen 0 | - | - | - | $40,877 | 2,418 | $34,542,754 | 0.1% | Mar 18, 2022 | Crunchyroll |
| 26 | Green Ghost and the Masters of the Stone | - | - | - | $36,784 | 135 | $113,685 | 32.4% | Apr 29, 2022 | Gravitas Ventures |
| 27 | Firebird | - | - | - | $34,978 | 89 | $144,118 | 24.3% | Apr 29, 2022 | Roadside Attractions |
| 28 | Diva 2022 Re-release | - | - | - | $33,768 | 2 | $73,411 | 46% | May 6, 2022 | Rialto Pictures |
| 29 | Dog | - | - | - | $29,484 | 3,827 | $61,778,069 | <0.1% | Feb 18, 2022 | United Artists Releasing |
| 30 | Remembering Heaven | - | - | - | $22,665 | 14 | $40,907 | 55.4% | May 6, 2022 | Purdie Distribution |
| 31 | Hit the Road | - | - | - | $18,212 | 432 | $151,018 | 12.1% | Apr 22, 2022 | Kino Lorber |
| 32 | On the Count of Three | - | - | - | $14,100 | 19 | $54,515 | 25.9% | May 13, 2022 | United Artists Releasing |
| 33 | Lux Æterna | - | - | - | $12,956 | 25 | $50,027 | 25.9% | May 6, 2022 | Yellow Veil Pictures |
| 34 | The Automat | - | - | - | $11,577 | 20 | $257,371 | 4.5% | Feb 18, 2022 | Slice of Pie |
| 35 | Hatching | - | - | - | $10,939 | 190 | $182,925 | 6% | Apr 29, 2022 | IFC Films |
| 36 | Pleasure | - | - | - | $10,330 | 44 | $106,789 | 9.7% | May 13, 2022 | Neon |
| 37 | In Front of Your Face | - | - | - | $9,150 | 1 | $9,150 | 100% | May 6, 2022 | The Cinema Guild |
| 38 | Montana Story | - | - | - | $8,743 | 290 | $292,915 | 3% | May 13, 2022 | Bleecker Street Media |
| 39 | The Rose Maker | - | - | - | $8,602 | 26 | $119,160 | 7.2% | Apr 1, 2022 | Music Box Films |
| 40 | Love in Kilnerry | - | - | - | $8,366 | 11 | $213,099 | 3.9% | Apr 8, 2022 | Archway Pictures |
| 41 | Anaïs in Love | - | - | - | $8,256 | 55 | $42,941 | 19.2% | Apr 29, 2022 | Magnolia Pictures |
| 42 | We're All Going to the World's Fair | - | - | - | $5,824 | 9 | $101,178 | 5.8% | Apr 15, 2022 | Utopia |
| 43 | Around the World in 80 Days | - | - | - | $4,630 | 86 | $48,757 | 9.5% | May 12, 2022 | Viva Pictures |
| 44 | The Innocents | - | - | - | $4,115 | 32 | $30,053 | 13.7% | May 13, 2022 | IFC Films |
| 45 | Mississippi Masala 2022 Re-release | - | - | - | $4,052 | 7 | $23,729 | 17.1% | Apr 15, 2022 | Janus Films |
| 46 | The Tale of King Crab | - | - | - | $2,706 | 9 | $26,919 | 10.1% | Apr 15, 2022 | Oscilloscope |
| 47 | Paris, 13th District | - | - | - | $2,648 | 67 | $73,118 | 3.6% | Apr 15, 2022 | IFC Films |
| 48 | Mothering Sunday | - | - | - | $2,628 | 293 | $275,352 | 1% | Mar 25, 2022 | Sony Pictures Classics |
| 49 | Take Me to the River: New Orleans | - | - | - | $2,544 | 33 | $43,563 | 5.8% | Apr 22, 2022 | N/A |
| 50 | The Sound of Violet | - | - | - | $1,928 | 29 | $32,333 | 6% | Apr 29, 2022 | Atlas Distribution Company |
| 51 | Jazz Fest: A New Orleans Story | - | - | - | $1,550 | 302 | $179,005 | 0.9% | May 13, 2022 | Sony Pictures Releasing |
| 52 | Waterman | - | - | - | $1,488 | 44 | $316,848 | 0.5% | Apr 1, 2022 | Purdie Distribution |
| 53 | Charlotte | - | - | - | $1,101 | 20 | $18,520 | 5.9% | Apr 22, 2022 | Good Deed Entertainment |
| 54 | The Conversation 2022 Re-release | - | - | - | $909 | 19 | $143,329 | 0.6% | May 6, 2022 | Rialto Pictures |
| 55 | Cow | - | - | - | $613 | 32 | $22,504 | 2.7% | Apr 8, 2022 | IFC Films |
| 56 | Kamikaze Hearts | - | - | - | $522 | 3 | $6,669 | 7.8% | May 13, 2022 | N/A |
| 57 | L'Arracheuse de temps | - | - | - | $517 | 72 | $750,623 | <0.1% | Nov 19, 2021 | Entertainment One |
| 58 | Ahed's Knee | - | - | - | $510 | 18 | $52,702 | 1% | Mar 18, 2022 | Kino Lorber |
| 59 | Aline | - | - | - | $404 | 72 | $667,815 | <0.1% | Nov 26, 2021 | Roadside Attractions |
| 60 | Stunt Rock 2022 Re-release | - | - | - | $272 | 15 | $9,530 | 2.9% | Mar 25, 2022 | Kino Lorber |
| 61 | Strawberry Mansion | - | - | - | $178 | 28 | $97,526 | 0.2% | Feb 18, 2022 | Music Box Films |
| 62 | I've Heard the Mermaids Singing 2022 Re-release | - | - | - | $161 | 4 | $6,903 | 2.3% | Mar 11, 2022 | Kino Lorber |
| 63 | Bronco Bullfrog 2022 Re-release | - | - | - | $159 | 2 | $13,171 | 1.2% | Mar 25, 2022 | Seventy-Seven |
| 64 | Writing with Fire | - | - | - | $146 | 9 | $28,262 | 0.5% | Nov 26, 2021 | Music Box Films |
