| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Doctor Strange in the Multiverse of Madness | - | - | - | $306,621,490 | 4,534 | $411,331,607 | 74.5% | May 6, 2022 | Walt Disney Studios Motion Pictures |
| 2 | The Bad Guys | - | - | - | $19,984,030 | 4,042 | $97,459,240 | 20.5% | Apr 22, 2022 | Universal Pictures |
| 3 | Sonic the Hedgehog 2 | - | - | - | $13,049,249 | 4,258 | $190,872,904 | 6.8% | Apr 8, 2022 | Paramount Pictures |
| 4 | Everything Everywhere All at Once | - | - | - | $9,903,756 | 2,220 | $77,191,785 | 12.8% | Mar 25, 2022 | A24 |
| 5 | Fantastic Beasts: The Secrets of Dumbledore | - | - | - | $8,874,756 | 4,245 | $95,850,844 | 9.3% | Apr 15, 2022 | Warner Bros. |
| 6 | The Northman | - | - | - | $6,567,475 | 3,284 | $34,233,110 | 19.2% | Apr 22, 2022 | Focus Features |
| 7 | The Lost City | - | - | - | $5,732,154 | 4,283 | $105,344,029 | 5.4% | Mar 25, 2022 | Paramount Pictures |
| 8 | Firestarter | - | - | - | $4,799,100 | 3,413 | $9,739,250 | 49.3% | May 13, 2022 | Universal Pictures |
| 9 | The Unbearable Weight of Massive Talent | - | - | - | $3,766,208 | 3,036 | $20,300,157 | 18.6% | Apr 22, 2022 | Lionsgate |
| 10 | Memory | - | - | - | $2,638,904 | 2,555 | $7,329,043 | 36% | Apr 29, 2022 | Open Road Films (II) |
| 11 | Father Stu | - | - | - | $1,759,538 | 2,705 | $20,884,796 | 8.4% | Apr 13, 2022 | Sony Pictures Releasing |
| 12 | Family Camp | - | - | - | $1,749,668 | 1,057 | $3,973,263 | 44% | May 13, 2022 | Roadside Attractions |
| 13 | Morbius | - | - | - | $1,109,947 | 4,268 | $73,865,530 | 1.5% | Apr 1, 2022 | Columbia Pictures |
| 14 | The Duke | - | - | - | $843,572 | 353 | $1,526,970 | 55.2% | Apr 22, 2022 | Sony Pictures Classics |
| 15 | Uncharted | - | - | - | $805,595 | 4,275 | $148,648,820 | 0.5% | Feb 18, 2022 | Sony Pictures Releasing |
| 16 | Ambulance | - | - | - | $666,120 | 3,412 | $22,781,115 | 2.9% | Apr 8, 2022 | Universal Pictures |
| 17 | Petite Maman | - | - | - | $484,881 | 224 | $829,065 | 58.5% | Apr 22, 2022 | Neon |
| 18 | The Batman | - | - | - | $184,099 | 4,417 | $369,345,583 | <0.1% | Mar 4, 2022 | Warner Bros. |
| 19 | ¿Y cómo es él? | - | - | - | $168,135 | 325 | $1,500,636 | 11.2% | Apr 22, 2022 | Lionsgate |
| 20 | Happening | - | - | - | $133,850 | 188 | $181,023 | 73.9% | May 6, 2022 | IFC Films |
| 21 | Spider-Man: No Way Home | - | - | - | $91,322 | 4,336 | $804,793,477 | <0.1% | Dec 17, 2021 | Sony Pictures Releasing |
| 22 | Eiffel | - | - | - | $68,598 | 308 | $444,814 | 15.4% | Apr 29, 2022 | Blue Fox Entertainment |
| 23 | Inland Empire 2022 Re-release | - | - | - | $54,885 | 14 | $253,523 | 21.6% | Apr 8, 2022 | Janus Films |
| 24 | On the Count of Three | - | - | - | $50,620 | 19 | $54,515 | 92.9% | May 13, 2022 | United Artists Releasing |
| 25 | Vortex | - | - | - | $49,359 | 39 | $145,708 | 33.9% | May 6, 2022 | Utopia |
| 26 | Firebird | - | - | - | $47,401 | 89 | $144,118 | 32.9% | Apr 29, 2022 | Roadside Attractions |
| 27 | Green Ghost and the Masters of the Stone | - | - | - | $46,917 | 135 | $113,685 | 41.3% | Apr 29, 2022 | Gravitas Ventures |
| 28 | Jujutsu Kaisen 0 | - | - | - | $40,877 | 2,418 | $34,542,754 | 0.1% | Mar 18, 2022 | Crunchyroll |
| 29 | Diva 2022 Re-release | - | - | - | $38,688 | 2 | $73,411 | 52.7% | May 6, 2022 | Rialto Pictures |
| 30 | Hit the Road | - | - | - | $32,362 | 432 | $151,018 | 21.4% | Apr 22, 2022 | Kino Lorber |
| 31 | Dog | - | - | - | $29,484 | 3,827 | $61,778,069 | <0.1% | Feb 18, 2022 | United Artists Releasing |
| 32 | Remembering Heaven | - | - | - | $28,249 | 14 | $40,907 | 69.1% | May 6, 2022 | Purdie Distribution |
| 33 | Around the World in 80 Days | - | - | - | $27,780 | 86 | $48,757 | 57% | May 12, 2022 | Viva Pictures |
| 34 | The Automat | - | - | - | $23,232 | 20 | $257,371 | 9% | Feb 18, 2022 | Slice of Pie |
| 35 | Montana Story | - | - | - | $21,166 | 290 | $292,915 | 7.2% | May 13, 2022 | Bleecker Street Media |
| 36 | Pleasure | - | - | - | $19,977 | 44 | $106,789 | 18.7% | May 13, 2022 | Neon |
| 37 | Lux Æterna | - | - | - | $18,736 | 25 | $50,027 | 37.5% | May 6, 2022 | Yellow Veil Pictures |
| 38 | The Innocents | - | - | - | $17,470 | 32 | $30,053 | 58.1% | May 13, 2022 | IFC Films |
| 39 | Take Me to the River: New Orleans | - | - | - | $14,024 | 33 | $43,563 | 32.2% | Apr 22, 2022 | N/A |
| 40 | Love in Kilnerry | - | - | - | $13,850 | 11 | $213,099 | 6.5% | Apr 8, 2022 | Archway Pictures |
| 41 | Hatching | - | - | - | $12,154 | 190 | $182,925 | 6.6% | Apr 29, 2022 | IFC Films |
| 42 | The Rose Maker | - | - | - | $12,072 | 26 | $119,160 | 10.1% | Apr 1, 2022 | Music Box Films |
| 43 | Anaïs in Love | - | - | - | $9,466 | 55 | $42,941 | 22% | Apr 29, 2022 | Magnolia Pictures |
| 44 | Jazz Fest: A New Orleans Story | - | - | - | $9,300 | 302 | $179,005 | 5.2% | May 13, 2022 | Sony Pictures Releasing |
| 45 | In Front of Your Face | - | - | - | $9,150 | 1 | $9,150 | 100% | May 6, 2022 | The Cinema Guild |
| 46 | We're All Going to the World's Fair | - | - | - | $8,904 | 9 | $101,178 | 8.8% | Apr 15, 2022 | Utopia |
| 47 | The Tale of King Crab | - | - | - | $5,186 | 9 | $26,919 | 19.3% | Apr 15, 2022 | Oscilloscope |
| 48 | Mothering Sunday | - | - | - | $4,398 | 293 | $275,352 | 1.6% | Mar 25, 2022 | Sony Pictures Classics |
| 49 | Mississippi Masala 2022 Re-release | - | - | - | $4,052 | 7 | $23,729 | 17.1% | Apr 15, 2022 | Janus Films |
| 50 | Paris, 13th District | - | - | - | $3,543 | 67 | $73,118 | 4.8% | Apr 15, 2022 | IFC Films |
| 51 | Kamikaze Hearts | - | - | - | $3,132 | 3 | $6,669 | 47% | May 13, 2022 | N/A |
| 52 | The Sound of Violet | - | - | - | $2,949 | 29 | $32,333 | 9.1% | Apr 29, 2022 | Atlas Distribution Company |
| 53 | The Conversation 2022 Re-release | - | - | - | $2,267 | 19 | $143,329 | 1.6% | May 6, 2022 | Rialto Pictures |
| 54 | Waterman | - | - | - | $1,488 | 44 | $316,848 | 0.5% | Apr 1, 2022 | Purdie Distribution |
| 55 | Charlotte | - | - | - | $1,101 | 20 | $18,520 | 5.9% | Apr 22, 2022 | Good Deed Entertainment |
| 56 | Strawberry Mansion | - | - | - | $1,068 | 28 | $97,526 | 1.1% | Feb 18, 2022 | Music Box Films |
| 57 | Stunt Rock 2022 Re-release | - | - | - | $992 | 15 | $9,530 | 10.4% | Mar 25, 2022 | Kino Lorber |
| 58 | Cow | - | - | - | $613 | 32 | $22,504 | 2.7% | Apr 8, 2022 | IFC Films |
| 59 | L'Arracheuse de temps | - | - | - | $517 | 72 | $750,623 | <0.1% | Nov 19, 2021 | Entertainment One |
| 60 | Ahed's Knee | - | - | - | $510 | 18 | $52,702 | 1% | Mar 18, 2022 | Kino Lorber |
| 61 | Aline | - | - | - | $404 | 72 | $667,815 | <0.1% | Nov 26, 2021 | Roadside Attractions |
| 62 | I've Heard the Mermaids Singing 2022 Re-release | - | - | - | $366 | 4 | $6,903 | 5.3% | Mar 11, 2022 | Kino Lorber |
| 63 | Bronco Bullfrog 2022 Re-release | - | - | - | $159 | 2 | $13,171 | 1.2% | Mar 25, 2022 | Seventy-Seven |
| 64 | Writing with Fire | - | - | - | $146 | 9 | $28,262 | 0.5% | Nov 26, 2021 | Music Box Films |
