| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | The Mummy Returns | - | - | - | $124,224,810 | 3,553 | $202,019,785 | 61.5% | May 4, 2001 | Universal Pictures |
| 2 | Bridget Jones's Diary | - | - | - | $9,205,628 | 2,547 | $71,543,427 | 12.9% | Apr 13, 2001 | Miramax |
| 3 | Driven | - | - | - | $8,404,073 | 2,905 | $32,720,065 | 25.7% | Apr 27, 2001 | Warner Bros. |
| 4 | Along Came a Spider | - | - | - | $5,721,009 | 2,573 | $74,078,174 | 7.7% | Apr 6, 2001 | Paramount Pictures |
| 5 | Spy Kids | - | - | - | $4,879,299 | 3,191 | $112,719,001 | 4.3% | Mar 30, 2001 | Miramax |
| 6 | Blow | - | - | - | $4,298,917 | 2,249 | $52,990,775 | 8.1% | Apr 6, 2001 | New Line Cinema |
| 7 | Crocodile Dundee in Los Angeles | - | - | - | $4,132,384 | 2,166 | $25,635,682 | 16.1% | Apr 20, 2001 | Paramount Pictures |
| 8 | A Knight's Tale | - | - | - | $3,890,450 | 2,980 | $56,569,702 | 6.9% | May 11, 2001 | Sony Pictures Releasing |
| 9 | Joe Dirt | - | - | - | $2,626,250 | 2,638 | $27,087,695 | 9.7% | Apr 11, 2001 | Sony Pictures Releasing |
| 10 | The Forsaken | - | - | - | $2,512,746 | 1,514 | $7,288,451 | 34.5% | Apr 27, 2001 | Screen Gems |
| 11 | Town & Country | - | - | - | $2,496,079 | 2,222 | $6,719,973 | 37.1% | Apr 27, 2001 | New Line Cinema |
| 12 | One Night at McCool's | - | - | - | $2,456,598 | 1,818 | $6,290,673 | 39.1% | Apr 27, 2001 | USA Films |
| 13 | Kingdom Come | - | - | - | $2,308,557 | 1,111 | $23,249,649 | 9.9% | Apr 11, 2001 | Fox Searchlight Pictures |
| 14 | Memento | - | - | - | $2,120,899 | 531 | $25,544,867 | 8.3% | Mar 16, 2001 | Newmarket Films |
| 15 | Freddy Got Fingered | - | - | - | $1,786,872 | 2,271 | $14,254,993 | 12.5% | Apr 20, 2001 | 20th Century Fox |
| 16 | Enemy at the Gates | - | - | - | $1,567,964 | 1,724 | $51,401,758 | 3.1% | Mar 16, 2001 | Paramount Pictures |
| 17 | The Tailor of Panama | - | - | - | $1,521,972 | 441 | $13,729,742 | 11.1% | Mar 30, 2001 | Sony Pictures Releasing |
| 18 | Crouching Tiger, Hidden Dragon | - | - | - | $1,430,856 | 2,027 | $128,078,872 | 1.1% | Dec 8, 2000 | Sony Pictures Classics |
| 19 | Traffic | - | - | - | $1,015,371 | 1,755 | $124,115,725 | 0.8% | Dec 27, 2000 | USA Films |
| 20 | Heartbreakers | - | - | - | $931,274 | 2,751 | $40,336,607 | 2.3% | Mar 23, 2001 | Metro-Goldwyn-Mayer (MGM) |
| 21 | Amores Perros | - | - | - | $894,720 | 187 | $5,408,467 | 16.5% | Mar 30, 2001 | Lionsgate |
| 22 | Josie and the Pussycats | - | - | - | $840,055 | 2,558 | $14,271,015 | 5.9% | Apr 11, 2001 | Universal Pictures |
| 23 | O Brother, Where Art Thou? | - | - | - | $820,861 | 847 | $45,512,588 | 1.8% | Dec 22, 2000 | Walt Disney Studios Motion Pictures |
| 24 | Someone Like You | - | - | - | $755,475 | 2,349 | $27,343,067 | 2.8% | Mar 30, 2001 | 20th Century Fox |
| 25 | The Mexican | - | - | - | $603,245 | 3,162 | $66,845,033 | 0.9% | Mar 2, 2001 | DreamWorks Distribution |
| 26 | Exit Wounds | - | - | - | $558,126 | 2,830 | $51,758,599 | 1.1% | Mar 16, 2001 | Warner Bros. |
| 27 | Chocolat | - | - | - | $509,538 | 1,928 | $71,509,363 | 0.7% | Dec 15, 2000 | Miramax |
| 28 | Cast Away | - | - | - | $502,280 | 3,061 | $233,632,142 | 0.2% | Dec 22, 2000 | 20th Century Fox |
| 29 | The Brothers | - | - | - | $454,807 | 1,378 | $27,457,409 | 1.7% | Mar 23, 2001 | Screen Gems |
| 30 | With a Friend Like Harry... | - | - | - | $437,018 | 220 | $3,830,441 | 11.4% | Apr 20, 2001 | Miramax |
| 31 | Hannibal | - | - | - | $389,982 | 3,292 | $165,092,268 | 0.2% | Feb 9, 2001 | Metro-Goldwyn-Mayer (MGM) |
| 32 | The Dish | - | - | - | $373,861 | 82 | $2,552,992 | 14.6% | Mar 16, 2001 | Warner Bros. |
| 33 | The Center of the World | - | - | - | $340,180 | 45 | $1,101,344 | 30.9% | Apr 20, 2001 | Artisan Entertainment |
| 34 | Pokémon 3 the Movie: Spell of the Unown | - | - | - | $318,687 | 2,675 | $17,052,128 | 1.9% | Apr 6, 2001 | Warner Bros. |
| 35 | Widow of St. Pierre | - | - | - | $303,471 | 83 | $3,193,889 | 9.5% | Mar 2, 2001 | Lionsgate |
| 36 | Pollock | - | - | - | $256,258 | 280 | $8,598,593 | 3% | Dec 15, 2000 | Sony Pictures Classics |
| 37 | Gabriela | - | - | - | $237,050 | 30 | $2,335,352 | 10.2% | Mar 16, 2001 | Power Point Films |
| 38 | Michael Jordan to the Max | - | - | - | $232,501 | 56 | $18,650,521 | 1.2% | May 5, 2000 | IMAX |
| 39 | The Golden Bowl | - | - | - | $225,467 | 117 | $3,050,532 | 7.4% | Apr 27, 2001 | Lionsgate |
| 40 | The House of Mirth | - | - | - | $224,062 | 63 | $3,043,284 | 7.4% | Dec 22, 2000 | Sony Pictures Classics |
| 41 | The Luzhin Defence | - | - | - | $215,964 | 49 | $1,053,070 | 20.5% | Apr 20, 2001 | Sony Pictures Classics |
| 42 | What Women Want | - | - | - | $212,024 | 3,092 | $182,811,707 | 0.1% | Dec 15, 2000 | Paramount Pictures |
| 43 | Shackleton's Antarctic Adventure | - | - | - | $199,990 | 26 | $15,553,324 | 1.3% | Feb 10, 2001 | WGBH Giant-Screen Films |
| 44 | The Emperor's New Groove | - | - | - | $194,486 | 2,887 | $89,302,687 | 0.2% | Dec 15, 2000 | Walt Disney Studios Motion Pictures |
| 45 | Down to Earth | - | - | - | $178,356 | 2,521 | $64,186,502 | 0.3% | Feb 16, 2001 | Paramount Pictures |
| 46 | Cirque du Soleil: Journey of Man | - | - | - | $175,352 | 22 | $15,627,434 | 1.1% | May 5, 2000 | Sony Pictures Classics |
| 47 | Double Take | - | - | - | $143,832 | 1,631 | $29,831,583 | 0.5% | Jan 12, 2001 | Walt Disney Studios Motion Pictures |
| 48 | The Claim | - | - | - | $138,387 | 29 | $669,258 | 20.7% | Dec 29, 2000 | Metro-Goldwyn-Mayer (MGM) |
| 49 | In the Mood for Love | - | - | - | $131,006 | 74 | $2,738,980 | 4.8% | Feb 2, 2001 | USA Films |
| 50 | The Circle | - | - | - | $105,709 | 16 | $440,554 | 24% | Mar 9, 2001 | WinStar Cinema |
| 51 | You Can Count on Me | - | - | - | $104,592 | 150 | $9,416,804 | 1.1% | Nov 10, 2000 | Paramount Classics |
| 52 | The Trumpet of the Swan | - | - | - | $102,202 | 125 | $102,202 | 100% | May 11, 2001 | Sony Pictures Releasing |
| 53 | Keep the River on Your Right: A Modern Cannibal Tale | - | - | - | $87,530 | 15 | $373,366 | 23.4% | Mar 30, 2001 | IFC Films |
| 54 | See Spot Run | - | - | - | $87,090 | 2,656 | $33,357,476 | 0.3% | Mar 2, 2001 | Warner Bros. |
| 55 | CyberWorld | - | - | - | $85,025 | 38 | $11,253,900 | 0.8% | Oct 6, 2000 | IMAX |
| 56 | Miss Congeniality | - | - | - | $78,874 | 2,668 | $106,807,667 | <0.1% | Dec 22, 2000 | Warner Bros. |
| 57 | Just Visiting | - | - | - | $78,305 | 1,590 | $4,781,539 | 1.6% | Apr 6, 2001 | Walt Disney Studios Motion Pictures |
| 58 | All Access: Front Row. Backstage. Live! | - | - | - | $65,899 | 35 | $992,683 | 6.6% | Apr 6, 2001 | IMAX |
| 59 | Bread and Roses | - | - | - | $59,850 | 39 | $533,479 | 11.2% | May 11, 2001 | Lionsgate |
| 60 | Brigham City | - | - | - | $55,515 | 55 | $852,206 | 6.5% | Apr 6, 2001 | Excel Entertainment |
| 61 | About Adam | - | - | - | $51,095 | 11 | $159,668 | 32% | May 11, 2001 | Miramax |
| 62 | Himalaya 2001 Re-release | - | - | - | $45,070 | 34 | $2,487,878 | 1.8% | Mar 30, 2001 | Kino International |
| 63 | The Closet | - | - | - | $35,986 | 145 | $6,678,894 | 0.5% | Jun 6, 2001 | Miramax |
| 64 | Pavilion of Women | - | - | - | $33,282 | 9 | $36,992 | 90% | May 4, 2001 | Focus Features |
| 65 | Under the Sand | - | - | - | $32,657 | 25 | $1,452,698 | 2.2% | May 4, 2001 | WinStar Cinema |
| 66 | T-Rex: Back to the Cretaceous | - | - | - | $27,541 | 38 | $53,354,743 | <0.1% | Oct 23, 1998 | IMAX |
| 67 | Startup.com | - | - | - | $25,182 | 35 | $1,283,356 | 2% | May 11, 2001 | Artisan Entertainment |
| 68 | Shrek | - | - | - | $20,099 | 3,715 | $268,200,241 | <0.1% | May 16, 2001 | DreamWorks Distribution |
| 69 | The King Is Alive | - | - | - | $17,929 | 6 | $17,929 | 100% | May 11, 2001 | IFC Films |
| 70 | Nora | - | - | - | $15,120 | 8 | $15,120 | 100% | May 4, 2001 | Andora Pictures International |
| 71 | Time and Tide | - | - | - | $10,770 | 1 | $10,770 | 100% | May 4, 2001 | Sony Pictures Releasing |
| 72 | The Caveman's Valentine | - | - | - | $5,784 | 59 | $687,194 | 0.8% | Mar 2, 2001 | Focus Features |
| 73 | Beautiful Creatures | - | - | - | $2,825 | 12 | $55,835 | 5.1% | Apr 6, 2001 | Focus Features |
| 74 | Gladiator | - | - | - | $542 | 3,188 | $187,705,427 | <0.1% | May 5, 2000 | DreamWorks Distribution |
| 75 | Rat | - | - | - | $378 | 1 | $2,630 | 14.4% | Apr 27, 2001 | Focus Features |
