| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | The Mummy Returns | - | - | - | $94,097,480 | 3,553 | $202,019,785 | 46.6% | May 4, 2001 | Universal Pictures |
| 2 | Bridget Jones's Diary | - | - | - | $8,687,459 | 2,547 | $71,543,427 | 12.1% | Apr 13, 2001 | Miramax |
| 3 | Driven | - | - | - | $8,170,899 | 2,905 | $32,720,065 | 25% | Apr 27, 2001 | Warner Bros. |
| 4 | Along Came a Spider | - | - | - | $5,473,545 | 2,573 | $74,078,174 | 7.4% | Apr 6, 2001 | Paramount Pictures |
| 5 | Spy Kids | - | - | - | $4,890,019 | 3,191 | $112,719,001 | 4.3% | Mar 30, 2001 | Miramax |
| 6 | Crocodile Dundee in Los Angeles | - | - | - | $4,103,679 | 2,166 | $25,635,682 | 16% | Apr 20, 2001 | Paramount Pictures |
| 7 | Blow | - | - | - | $3,900,548 | 2,249 | $52,990,775 | 7.4% | Apr 6, 2001 | New Line Cinema |
| 8 | A Knight's Tale | - | - | - | $3,066,619 | 2,980 | $56,569,702 | 5.4% | May 11, 2001 | Sony Pictures Releasing |
| 9 | The Forsaken | - | - | - | $1,955,576 | 1,514 | $7,288,451 | 26.8% | Apr 27, 2001 | Screen Gems |
| 10 | Memento | - | - | - | $1,935,720 | 531 | $25,544,867 | 7.6% | Mar 16, 2001 | Newmarket Films |
| 11 | Town & Country | - | - | - | $1,933,989 | 2,222 | $6,719,973 | 28.8% | Apr 27, 2001 | New Line Cinema |
| 12 | Joe Dirt | - | - | - | $1,913,505 | 2,638 | $27,087,695 | 7.1% | Apr 11, 2001 | Sony Pictures Releasing |
| 13 | One Night at McCool's | - | - | - | $1,911,373 | 1,818 | $6,290,673 | 30.4% | Apr 27, 2001 | USA Films |
| 14 | Kingdom Come | - | - | - | $1,564,217 | 1,111 | $23,249,649 | 6.7% | Apr 11, 2001 | Fox Searchlight Pictures |
| 15 | The Tailor of Panama | - | - | - | $1,442,188 | 441 | $13,729,742 | 10.5% | Mar 30, 2001 | Sony Pictures Releasing |
| 16 | Freddy Got Fingered | - | - | - | $1,381,337 | 2,271 | $14,254,993 | 9.7% | Apr 20, 2001 | Twentieth Century Fox |
| 17 | Enemy at the Gates | - | - | - | $1,037,009 | 1,724 | $51,401,758 | 2% | Mar 16, 2001 | Paramount Pictures |
| 18 | Crouching Tiger, Hidden Dragon | - | - | - | $932,976 | 2,027 | $128,078,872 | 0.7% | Dec 8, 2000 | Sony Pictures Classics |
| 19 | Josie and the Pussycats | - | - | - | $660,235 | 2,558 | $14,271,015 | 4.6% | Apr 11, 2001 | Universal Pictures |
| 20 | Heartbreakers | - | - | - | $604,299 | 2,751 | $40,336,607 | 1.5% | Mar 23, 2001 | Metro-Goldwyn-Mayer (MGM) |
| 21 | Traffic | - | - | - | $580,471 | 1,755 | $124,115,725 | 0.5% | Dec 27, 2000 | USA Films |
| 22 | Amores Perros | - | - | - | $577,445 | 187 | $5,408,467 | 10.7% | Mar 30, 2001 | Lionsgate |
| 23 | Someone Like You | - | - | - | $537,400 | 2,349 | $27,343,067 | 2% | Mar 30, 2001 | Twentieth Century Fox |
| 24 | O Brother, Where Art Thou? | - | - | - | $504,911 | 847 | $45,512,588 | 1.1% | Dec 22, 2000 | Walt Disney Studios Motion Pictures |
| 25 | The Mexican | - | - | - | $421,262 | 3,162 | $66,845,033 | 0.6% | Mar 2, 2001 | DreamWorks Distribution |
| 26 | Chocolat | - | - | - | $413,959 | 1,928 | $71,509,363 | 0.6% | Dec 15, 2000 | Miramax |
| 27 | Exit Wounds | - | - | - | $373,821 | 2,830 | $51,758,599 | 0.7% | Mar 16, 2001 | Warner Bros. |
| 28 | Cast Away | - | - | - | $325,505 | 3,061 | $233,632,142 | 0.1% | Dec 22, 2000 | Twentieth Century Fox |
| 29 | The Brothers | - | - | - | $316,332 | 1,378 | $27,457,409 | 1.2% | Mar 23, 2001 | Screen Gems |
| 30 | Hannibal | - | - | - | $258,067 | 3,292 | $165,092,268 | 0.2% | Feb 9, 2001 | Metro-Goldwyn-Mayer (MGM) |
| 31 | With a Friend Like Harry... | - | - | - | $243,323 | 220 | $3,830,441 | 6.4% | Apr 20, 2001 | Miramax |
| 32 | The Dish | - | - | - | $237,531 | 82 | $2,552,992 | 9.3% | Mar 16, 2001 | Warner Bros. |
| 33 | Pokémon 3 the Movie: Spell of the Unown | - | - | - | $232,727 | 2,675 | $17,052,128 | 1.4% | Apr 6, 2001 | Warner Bros. |
| 34 | The Center of the World | - | - | - | $206,580 | 45 | $1,101,344 | 18.8% | Apr 20, 2001 | Artisan Entertainment |
| 35 | Widow of St. Pierre | - | - | - | $197,171 | 83 | $3,193,889 | 6.2% | Mar 2, 2001 | Lionsgate |
| 36 | Pollock | - | - | - | $174,613 | 280 | $8,598,593 | 2% | Dec 15, 2000 | Sony Pictures Classics |
| 37 | What Women Want | - | - | - | $153,374 | 3,092 | $182,811,707 | <0.1% | Dec 15, 2000 | Paramount Pictures |
| 38 | Gabriela | - | - | - | $146,085 | 30 | $2,335,352 | 6.3% | Mar 16, 2001 | Power Point Films |
| 39 | The Luzhin Defence | - | - | - | $135,534 | 49 | $1,053,070 | 12.9% | Apr 20, 2001 | Sony Pictures Classics |
| 40 | The Emperor's New Groove | - | - | - | $132,421 | 2,887 | $89,302,687 | 0.1% | Dec 15, 2000 | Walt Disney Studios Motion Pictures |
| 41 | In the Mood for Love | - | - | - | $131,006 | 74 | $2,738,980 | 4.8% | Feb 2, 2001 | USA Films |
| 42 | Michael Jordan to the Max | - | - | - | $127,551 | 56 | $18,650,521 | 0.7% | May 5, 2000 | IMAX |
| 43 | Shackleton's Antarctic Adventure | - | - | - | $127,370 | 26 | $15,553,324 | 0.8% | Feb 10, 2001 | WGBH Giant-Screen Films |
| 44 | Down to Earth | - | - | - | $119,401 | 2,521 | $64,186,502 | 0.2% | Feb 16, 2001 | Paramount Pictures |
| 45 | The Golden Bowl | - | - | - | $115,247 | 117 | $3,050,532 | 3.8% | Apr 27, 2001 | Lionsgate |
| 46 | Cirque du Soleil: Journey of Man | - | - | - | $104,882 | 22 | $15,627,434 | 0.7% | May 5, 2000 | Sony Pictures Classics |
| 47 | Double Take | - | - | - | $94,592 | 1,631 | $29,831,583 | 0.3% | Jan 12, 2001 | Walt Disney Studios Motion Pictures |
| 48 | The Claim | - | - | - | $94,012 | 29 | $669,258 | 14% | Dec 29, 2000 | Metro-Goldwyn-Mayer (MGM) |
| 49 | Keep the River on Your Right: A Modern Cannibal Tale | - | - | - | $87,530 | 15 | $373,366 | 23.4% | Mar 30, 2001 | IFC Films |
| 50 | See Spot Run | - | - | - | $87,090 | 2,656 | $33,357,476 | 0.3% | Mar 2, 2001 | Warner Bros. |
| 51 | Miss Congeniality | - | - | - | $78,874 | 2,668 | $106,807,667 | <0.1% | Dec 22, 2000 | Warner Bros. |
| 52 | Just Visiting | - | - | - | $78,305 | 1,590 | $4,781,539 | 1.6% | Apr 6, 2001 | Walt Disney Studios Motion Pictures |
| 53 | The Circle | - | - | - | $67,774 | 16 | $440,554 | 15.4% | Mar 9, 2001 | WinStar Cinema |
| 54 | All Access: Front Row. Backstage. Live! | - | - | - | $65,899 | 35 | $992,683 | 6.6% | Apr 6, 2001 | IMAX |
| 55 | The House of Mirth | - | - | - | $55,897 | 63 | $3,043,284 | 1.8% | Dec 22, 2000 | Sony Pictures Classics |
| 56 | Brigham City | - | - | - | $55,515 | 55 | $852,206 | 6.5% | Apr 6, 2001 | Excel Entertainment |
| 57 | You Can Count on Me | - | - | - | $45,642 | 150 | $9,416,804 | 0.5% | Nov 10, 2000 | Paramount Classics |
| 58 | Himalaya 2001 Re-release | - | - | - | $45,070 | 34 | $2,487,878 | 1.8% | Mar 30, 2001 | Kino International |
| 59 | The Closet | - | - | - | $35,986 | 145 | $6,678,894 | 0.5% | Jun 6, 2001 | Miramax |
| 60 | Under the Sand | - | - | - | $32,657 | 25 | $1,452,698 | 2.2% | May 4, 2001 | WinStar Cinema |
| 61 | T-Rex: Back to the Cretaceous | - | - | - | $27,541 | 38 | $53,354,743 | <0.1% | Oct 23, 1998 | IMAX |
| 62 | Pavilion of Women | - | - | - | $25,835 | 9 | $36,992 | 69.8% | May 4, 2001 | Focus Features |
| 63 | CyberWorld | - | - | - | $21,310 | 38 | $11,253,900 | 0.2% | Oct 6, 2000 | IMAX |
| 64 | About Adam | - | - | - | $16,375 | 11 | $159,668 | 10.3% | May 11, 2001 | Miramax |
| 65 | Nora | - | - | - | $15,120 | 8 | $15,120 | 100% | May 4, 2001 | Andora Pictures International |
| 66 | Time and Tide | - | - | - | $10,770 | 1 | $10,770 | 100% | May 4, 2001 | Sony Pictures Releasing |
| 67 | Bread and Roses | - | - | - | $9,975 | 39 | $533,479 | 1.9% | May 11, 2001 | Lionsgate |
| 68 | Shrek | - | - | - | $5,655 | 3,715 | $268,200,241 | <0.1% | May 16, 2001 | DreamWorks Distribution |
| 69 | Startup.com | - | - | - | $4,197 | 35 | $1,283,356 | 0.3% | May 11, 2001 | Artisan Entertainment |
| 70 | The Caveman's Valentine | - | - | - | $4,124 | 59 | $687,194 | 0.6% | Mar 2, 2001 | Focus Features |
| 71 | Beautiful Creatures | - | - | - | $1,927 | 12 | $55,835 | 3.5% | Apr 6, 2001 | Focus Features |
| 72 | Gladiator | - | - | - | $542 | 3,188 | $187,705,427 | <0.1% | May 5, 2000 | DreamWorks Distribution |
| 73 | Rat | - | - | - | $378 | 1 | $2,630 | 14.4% | Apr 27, 2001 | Focus Features |
