| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Cast Away | - | - | - | $35,024,952 | 3,061 | $233,632,142 | 15% | Dec 22, 2000 | Twentieth Century Fox |
| 2 | Traffic | - | - | - | $29,343,303 | 1,755 | $124,115,725 | 23.6% | Dec 27, 2000 | USA Films |
| 3 | What Women Want | - | - | - | $27,182,060 | 3,092 | $182,811,707 | 14.9% | Dec 15, 2000 | Paramount Pictures |
| 4 | Miss Congeniality | - | - | - | $22,940,521 | 2,668 | $106,807,667 | 21.5% | Dec 22, 2000 | Warner Bros. |
| 5 | Save the Last Dance | - | - | - | $16,641,000 | 2,570 | $91,057,006 | 18.3% | Jan 12, 2001 | Paramount Pictures |
| 6 | The Family Man | - | - | - | $15,584,555 | 2,441 | $75,793,305 | 20.6% | Dec 22, 2000 | Universal Pictures |
| 7 | The Emperor's New Groove | - | - | - | $11,137,546 | 2,887 | $89,302,687 | 12.5% | Dec 15, 2000 | Walt Disney Studios Motion Pictures |
| 8 | Crouching Tiger, Hidden Dragon | - | - | - | $10,806,822 | 2,027 | $128,078,872 | 8.4% | Dec 8, 2000 | Sony Pictures Classics |
| 9 | Vertical Limit | - | - | - | $7,502,624 | 2,602 | $69,243,859 | 10.8% | Dec 8, 2000 | Sony Pictures Releasing |
| 10 | Thirteen Days | - | - | - | $7,197,068 | 2,034 | $34,592,089 | 20.8% | Dec 22, 2000 | New Line Cinema |
| 11 | Finding Forrester | - | - | - | $6,804,679 | 2,002 | $51,804,714 | 13.1% | Dec 22, 2000 | Sony Pictures Releasing |
| 12 | Dracula 2000 | - | - | - | $6,176,693 | 2,204 | $33,022,767 | 18.7% | Dec 22, 2000 | Miramax |
| 13 | Dude, Where's My Car? | - | - | - | $5,327,359 | 2,100 | $46,729,800 | 11.4% | Dec 15, 2000 | Twentieth Century Fox |
| 14 | Double Take | - | - | - | $3,734,522 | 1,631 | $29,831,583 | 12.5% | Jan 12, 2001 | Walt Disney Studios Motion Pictures |
| 15 | All the Pretty Horses | - | - | - | $3,710,060 | 1,593 | $15,540,353 | 23.9% | Dec 25, 2000 | Miramax |
| 16 | How the Grinch Stole Christmas | - | - | - | $3,315,125 | 3,256 | $261,231,700 | 1.3% | Nov 17, 2000 | Universal Pictures |
| 17 | Chocolat | - | - | - | $2,987,970 | 1,928 | $71,509,363 | 4.2% | Dec 15, 2000 | Miramax |
| 18 | O Brother, Where Art Thou? | - | - | - | $2,912,142 | 847 | $45,512,588 | 6.4% | Dec 22, 2000 | Walt Disney Studios Motion Pictures |
| 19 | 102 Dalmatians | - | - | - | $2,258,991 | 2,704 | $66,957,026 | 3.4% | Nov 22, 2000 | Walt Disney Studios Motion Pictures |
| 20 | Unbreakable | - | - | - | $1,871,552 | 2,708 | $95,011,339 | 2% | Nov 22, 2000 | Walt Disney Studios Motion Pictures |
| 21 | Proof of Life | - | - | - | $1,814,769 | 2,705 | $32,598,931 | 5.6% | Dec 8, 2000 | Warner Bros. |
| 22 | Antitrust | - | - | - | $1,812,724 | 2,433 | $11,328,094 | 16% | Jan 12, 2001 | Metro-Goldwyn-Mayer (MGM) |
| 23 | Rugrats in Paris | - | - | - | $1,512,233 | 2,937 | $76,507,756 | 2% | Nov 17, 2000 | Paramount Pictures |
| 24 | State and Main | - | - | - | $1,219,316 | 462 | $6,944,471 | 17.6% | Dec 22, 2000 | Fine Line Features |
| 25 | Meet the Parents | - | - | - | $1,166,145 | 2,697 | $166,244,045 | 0.7% | Oct 6, 2000 | Universal Pictures |
| 26 | Encounter in the Third Dimension | - | - | - | $1,093,918 | 16 | $7,195,792 | 15.2% | Feb 26, 1999 | nWave Pictures |
| 27 | Quills | - | - | - | $1,031,435 | 223 | $7,065,332 | 14.6% | Nov 24, 2000 | Fox Searchlight Pictures |
| 28 | You Can Count on Me | - | - | - | $941,464 | 150 | $9,416,804 | 10% | Nov 10, 2000 | Paramount Classics |
| 29 | Billy Elliot | - | - | - | $798,031 | 510 | $21,995,263 | 3.6% | Oct 13, 2000 | Focus Features |
| 30 | Remember the Titans | - | - | - | $624,114 | 2,803 | $115,654,751 | 0.5% | Sep 29, 2000 | Walt Disney Studios Motion Pictures |
| 31 | Charlie's Angels | - | - | - | $546,822 | 3,037 | $125,305,545 | 0.4% | Nov 3, 2000 | Sony Pictures Releasing |
| 32 | Men of Honor | - | - | - | $461,445 | 2,188 | $48,818,921 | 0.9% | Nov 10, 2000 | Twentieth Century Fox |
| 33 | Dungeons & Dragons | - | - | - | $415,886 | 2,078 | $15,391,970 | 2.7% | Dec 8, 2000 | New Line Cinema |
| 34 | CyberWorld | - | - | - | $358,734 | 38 | $11,253,900 | 3.2% | Oct 6, 2000 | IMAX |
| 35 | Malena | - | - | - | $352,141 | 117 | $3,448,233 | 10.2% | Dec 22, 2000 | Miramax |
| 36 | Margaret Cho: I'm the One That I Want | - | - | - | $326,396 | 8 | $1,210,967 | 27% | Aug 4, 2000 | Cho Taussig Productions |
| 37 | Best in Show | - | - | - | $278,752 | 497 | $18,715,392 | 1.5% | Sep 29, 2000 | Warner Bros. |
| 38 | Little Nicky | - | - | - | $220,099 | 2,910 | $39,464,775 | 0.6% | Nov 10, 2000 | New Line Cinema |
| 39 | Before Night Falls | - | - | - | $178,544 | 127 | $4,242,892 | 4.2% | Dec 22, 2000 | Fine Line Features |
| 40 | Shadow of the Vampire | - | - | - | $174,182 | 513 | $8,293,784 | 2.1% | Dec 29, 2000 | Lionsgate |
| 41 | Michael Jordan to the Max | - | - | - | $168,521 | 56 | $18,650,521 | 0.9% | May 5, 2000 | IMAX |
| 42 | Space Cowboys | - | - | - | $163,345 | 2,835 | $90,464,773 | 0.2% | Aug 4, 2000 | Warner Bros. |
| 43 | The House of Mirth | - | - | - | $152,759 | 63 | $3,043,284 | 5% | Dec 22, 2000 | Sony Pictures Classics |
| 44 | Bedazzled | - | - | - | $150,041 | 2,571 | $37,886,980 | 0.4% | Oct 20, 2000 | Twentieth Century Fox |
| 45 | Red Planet | - | - | - | $138,382 | 2,703 | $17,480,890 | 0.8% | Nov 10, 2000 | Warner Bros. |
| 46 | Requiem for a Dream | - | - | - | $136,929 | 93 | $3,635,482 | 3.8% | Oct 6, 2000 | Artisan Entertainment |
| 47 | A Hard Day's Night | - | - | - | $136,423 | 63 | $965,351 | 14.1% | Dec 1, 2000 | Miramax |
| 48 | The 6th Day | - | - | - | $126,609 | 2,516 | $34,604,280 | 0.4% | Nov 17, 2000 | Sony Pictures Releasing |
| 49 | T-Rex: Back to the Cretaceous | - | - | - | $109,080 | 38 | $53,354,743 | 0.2% | Oct 23, 1998 | IMAX |
| 50 | Cirque du Soleil: Journey of Man | - | - | - | $105,337 | 22 | $15,627,434 | 0.7% | May 5, 2000 | Sony Pictures Classics |
| 51 | Bounce | - | - | - | $85,414 | 2,028 | $36,805,288 | 0.2% | Nov 17, 2000 | Miramax |
| 52 | Pay It Forward | - | - | - | $78,532 | 2,130 | $33,519,628 | 0.2% | Oct 20, 2000 | Warner Bros. |
| 53 | Galapagos | - | - | - | $72,630 | 14 | $18,630,372 | 0.4% | Oct 29, 1999 | IMAX |
| 54 | The Legend of Bagger Vance | - | - | - | $56,494 | 2,162 | $30,919,168 | 0.2% | Nov 3, 2000 | DreamWorks Distribution |
| 55 | Extreme | - | - | - | $51,514 | 21 | $12,475,172 | 0.4% | Apr 2, 1999 | IMAX |
| 56 | Mysteries of Egypt | - | - | - | $45,022 | 27 | $40,593,486 | 0.1% | Aug 21, 1998 | IMAX |
| 57 | Raju Chacha | - | - | - | $41,849 | 35 | $194,698 | 21.5% | Dec 29, 2000 | Eros Worldwide |
| 58 | Wonder Boys | - | - | - | $39,602 | 1,509 | $19,393,557 | 0.2% | Feb 23, 2000 | Paramount Pictures |
| 59 | What Lies Beneath | - | - | - | $39,560 | 2,925 | $155,464,351 | <0.1% | Jul 21, 2000 | DreamWorks Distribution |
| 60 | Panic | - | - | - | $37,735 | 11 | $779,137 | 4.8% | Dec 1, 2000 | Roxie Releasing |
| 61 | Seong Chun-hyang | - | - | - | $36,263 | 16 | $798,977 | 4.5% | Dec 29, 2000 | Lot 47 Films |
| 62 | The Contender | - | - | - | $35,694 | 1,639 | $17,872,723 | 0.2% | Oct 13, 2000 | DreamWorks Distribution |
| 63 | Catfish in Black Bean Sauce | - | - | - | $31,082 | 20 | $1,319,592 | 2.4% | Jun 9, 2000 | Iron Hill Pictures |
| 64 | Yi Yi | - | - | - | $19,987 | 15 | $1,136,776 | 1.8% | Oct 6, 2000 | WinStar Cinema |
| 65 | A Time for Drunken Horses | - | - | - | $18,121 | 21 | $587,654 | 3.1% | Oct 27, 2000 | - |
| 66 | An Everlasting Piece | - | - | - | $13,488 | 8 | $75,228 | 17.9% | Dec 22, 2000 | DreamWorks Distribution |
| 67 | Left Luggage | - | - | - | $11,843 | 7 | $1,069,540 | 1.1% | Sep 22, 2000 | Castle Hill Productions |
| 68 | The Log | - | - | - | $10,862 | 4 | $238,754 | 4.5% | Sep 29, 2000 | Empire Pictures Inc. |
| 69 | Khiladi 420 | - | - | - | $7,893 | 12 | $26,731 | 29.5% | Dec 29, 2000 | Eros Worldwide |
