| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Gladiator | - | - | - | $81,134,303 | 3,188 | $187,705,427 | 43.2% | May 5, 2000 | DreamWorks Distribution |
| 2 | U-571 | - | - | - | $17,454,880 | 2,820 | $77,122,415 | 22.6% | Apr 21, 2000 | Universal Pictures |
| 3 | Frequency | - | - | - | $13,770,963 | 2,631 | $45,010,278 | 30.6% | Apr 28, 2000 | New Line Cinema |
| 4 | The Flintstones in Viva Rock Vegas | - | - | - | $13,047,720 | 3,125 | $35,268,275 | 37% | Apr 28, 2000 | Universal Pictures |
| 5 | Battlefield Earth | - | - | - | $12,283,200 | 3,307 | $21,471,685 | 57.2% | May 12, 2000 | Warner Bros. |
| 6 | Where the Heart Is | - | - | - | $11,483,710 | 2,439 | $33,772,838 | 34% | Apr 28, 2000 | 20th Century Fox |
| 7 | Love & Basketball | - | - | - | $6,218,148 | 1,245 | $27,459,615 | 22.6% | Apr 21, 2000 | New Line Cinema |
| 8 | Keeping the Faith | - | - | - | $6,058,781 | 2,171 | $37,047,880 | 16.4% | Apr 14, 2000 | Walt Disney Studios Motion Pictures |
| 9 | I Dreamed of Africa | - | - | - | $5,187,632 | 2,112 | $6,651,522 | 78% | May 5, 2000 | Sony Pictures Releasing |
| 10 | Erin Brockovich | - | - | - | $5,057,175 | 3,070 | $125,595,205 | 4% | Mar 17, 2000 | Universal Pictures |
| 11 | Center Stage | - | - | - | $5,023,956 | 1,506 | $17,200,925 | 29.2% | May 12, 2000 | Sony Pictures Releasing |
| 12 | Screwed | - | - | - | $4,080,020 | 1,761 | $7,027,345 | 58.1% | May 12, 2000 | Universal Pictures |
| 13 | 28 Days | - | - | - | $3,960,704 | 2,523 | $37,170,488 | 10.7% | Apr 14, 2000 | Sony Pictures Releasing |
| 14 | Rules of Engagement | - | - | - | $3,741,347 | 3,220 | $61,335,230 | 6.1% | Apr 7, 2000 | Paramount Pictures |
| 15 | Final Destination | - | - | - | $3,416,473 | 2,587 | $53,331,147 | 6.4% | Mar 17, 2000 | New Line Cinema |
| 16 | Return to Me | - | - | - | $2,730,470 | 2,320 | $32,722,798 | 8.3% | Apr 7, 2000 | Metro-Goldwyn-Mayer (MGM) |
| 17 | The Road to El Dorado | - | - | - | $2,402,342 | 3,223 | $50,863,742 | 4.7% | Mar 31, 2000 | DreamWorks Distribution |
| 18 | Held Up | - | - | - | $2,026,494 | 688 | $4,705,631 | 43.1% | May 12, 2000 | Trimark Pictures |
| 19 | High Fidelity | - | - | - | $1,745,564 | 1,231 | $27,287,137 | 6.4% | Mar 31, 2000 | Walt Disney Studios Motion Pictures |
| 20 | Michael Jordan to the Max | - | - | - | $1,561,874 | 56 | $18,650,521 | 8.4% | May 5, 2000 | IMAX |
| 21 | The Skulls | - | - | - | $1,485,740 | 2,416 | $35,046,120 | 4.2% | Mar 31, 2000 | Universal Pictures |
| 22 | The Virgin Suicides | - | - | - | $1,268,196 | 275 | $4,906,229 | 25.8% | Apr 21, 2000 | Paramount Classics |
| 23 | Mysteries of Egypt | - | - | - | $1,166,964 | 27 | $40,593,486 | 2.9% | Aug 21, 1998 | IMAX |
| 24 | Romeo Must Die | - | - | - | $883,778 | 2,641 | $55,973,336 | 1.6% | Mar 22, 2000 | Warner Bros. |
| 25 | American Psycho | - | - | - | $878,849 | 1,242 | $15,070,285 | 5.8% | Apr 14, 2000 | Lionsgate |
| 26 | Up at the Villa | - | - | - | $801,232 | 112 | $2,933,161 | 27.3% | May 5, 2000 | USA Films |
| 27 | American Beauty | - | - | - | $744,481 | 1,990 | $130,096,601 | 0.6% | Sep 15, 1999 | DreamWorks Distribution |
| 28 | Scream 3 | - | - | - | $585,433 | 3,467 | $89,143,175 | 0.7% | Feb 4, 2000 | Dimension Films |
| 29 | East Is East | - | - | - | $549,043 | 157 | $4,177,818 | 13.1% | Apr 14, 2000 | Miramax |
| 30 | Gossip | - | - | - | $421,516 | 1,525 | $5,108,820 | 8.3% | Apr 21, 2000 | Warner Bros. |
| 31 | Galapagos | - | - | - | $411,349 | 14 | $18,630,372 | 2.2% | Oct 29, 1999 | IMAX |
| 32 | T-Rex: Back to the Cretaceous | - | - | - | $410,230 | 38 | $53,354,743 | 0.8% | Oct 23, 1998 | IMAX |
| 33 | Pitch Black | - | - | - | $403,399 | 1,930 | $39,240,659 | 1% | Feb 18, 2000 | USA Films |
| 34 | Toy Story 2 | - | - | - | $397,963 | 3,257 | $245,852,179 | 0.2% | Nov 19, 1999 | Walt Disney Studios Motion Pictures |
| 35 | East/West | - | - | - | $390,463 | 70 | $2,321,029 | 16.8% | Apr 7, 2000 | Sony Pictures Classics |
| 36 | Next Friday | - | - | - | $271,830 | 1,420 | $57,328,603 | 0.5% | Jan 12, 2000 | New Line Cinema |
| 37 | Timecode | - | - | - | $262,051 | 130 | $1,057,750 | 24.8% | Apr 28, 2000 | Sony Pictures Releasing |
| 38 | Ready to Rumble | - | - | - | $261,579 | 2,585 | $12,394,327 | 2.1% | Apr 7, 2000 | Warner Bros. |
| 39 | Cirque du Soleil: Journey of Man | - | - | - | $253,219 | 22 | $15,627,434 | 1.6% | May 5, 2000 | Sony Pictures Classics |
| 40 | Luminarias | - | - | - | $237,238 | 51 | $292,309 | 81.2% | May 5, 2000 | New Latin Pictures |
| 41 | The Ninth Gate | - | - | - | $231,187 | 1,694 | $18,661,336 | 1.2% | Mar 10, 2000 | Artisan Entertainment |
| 42 | The Big Kahuna | - | - | - | $229,373 | 309 | $3,165,544 | 7.2% | Apr 28, 2000 | Lionsgate |
| 43 | Siegfried & Roy: The Magic Box | - | - | - | $207,581 | 22 | $5,231,283 | 4% | Oct 1, 1999 | IMAX |
| 44 | The Cider House Rules | - | - | - | $202,715 | 1,738 | $57,545,092 | 0.4% | Dec 10, 1999 | Miramax |
| 45 | Alien Adventure | - | - | - | $175,451 | 10 | $8,959,784 | 2% | Aug 20, 1999 | nWave Pictures |
| 46 | Ghost Dog: The Way of the Samurai | - | - | - | $165,314 | 109 | $3,308,029 | 5% | Mar 3, 2000 | Artisan Entertainment |
| 47 | God's Army | - | - | - | $156,363 | 50 | $2,637,726 | 5.9% | Mar 10, 2000 | Zion Films |
| 48 | The Color of Paradise | - | - | - | $148,182 | 33 | $1,817,216 | 8.2% | Mar 31, 2000 | Sony Pictures Classics |
| 49 | Chal Mere Bhai | - | - | - | $141,939 | 25 | $199,227 | 71.2% | May 5, 2000 | Eros Worldwide |
| 50 | Where the Money Is | - | - | - | $133,664 | 1,538 | $5,661,798 | 2.4% | Apr 14, 2000 | USA Films |
| 51 | The Whole Nine Yards | - | - | - | $130,469 | 2,910 | $57,262,492 | 0.2% | Feb 18, 2000 | Warner Bros. |
| 52 | Bicentennial Man | - | - | - | $123,700 | 2,767 | $58,223,861 | 0.2% | Dec 17, 1999 | Walt Disney Studios Motion Pictures |
| 53 | The Other Conquest | - | - | - | $122,594 | 74 | $886,410 | 13.8% | Apr 21, 2000 | Hombre d'Oro |
| 54 | Croupier | - | - | - | $121,451 | 141 | $6,201,143 | 2% | Apr 21, 2000 | - |
| 55 | The Green Mile | - | - | - | $120,613 | 2,875 | $136,801,374 | <0.1% | Dec 10, 1999 | Warner Bros. |
| 56 | Galaxy Quest | - | - | - | $118,647 | 2,450 | $71,583,916 | 0.2% | Dec 25, 1999 | DreamWorks Distribution |
| 57 | My Dog Skip | - | - | - | $104,479 | 2,331 | $34,134,641 | 0.3% | Jan 14, 2000 | Warner Bros. |
| 58 | Joe Gould's Secret | - | - | - | $97,298 | 33 | $468,684 | 20.8% | Apr 7, 2000 | USA Films |
| 59 | Beyond the Mat | - | - | - | $95,180 | 298 | $2,053,648 | 4.6% | Oct 22, 1999 | Lionsgate |
| 60 | The Last September | - | - | - | $95,048 | 56 | $478,053 | 19.9% | Apr 21, 2000 | Trimark Pictures |
| 61 | Hamlet | - | - | - | $83,544 | 65 | $1,577,287 | 5.3% | May 12, 2000 | Miramax |
| 62 | Mission to Mars | - | - | - | $66,163 | 3,101 | $60,883,407 | 0.1% | Mar 10, 2000 | Walt Disney Studios Motion Pictures |
| 63 | The Sixth Sense | - | - | - | $65,323 | 2,821 | $293,506,292 | <0.1% | Aug 6, 1999 | Walt Disney Studios Motion Pictures |
| 64 | The Basket | - | - | - | $61,300 | 113 | $367,098 | 16.7% | Aug 20, 1999 | North by Northwest Entertainment |
| 65 | Bossa Nova | - | - | - | $56,382 | 59 | $1,823,297 | 3.1% | Apr 28, 2000 | Sony Pictures Releasing |
| 66 | Me Myself I | - | - | - | $52,714 | 59 | $369,975 | 14.2% | Apr 7, 2000 | Sony Pictures Classics |
| 67 | All About My Mother | - | - | - | $50,934 | 145 | $8,272,296 | 0.6% | Nov 5, 1999 | Sony Pictures Classics |
| 68 | The Tigger Movie | - | - | - | $49,786 | 2,818 | $45,554,533 | 0.1% | Feb 11, 2000 | Walt Disney Studios Motion Pictures |
| 69 | The Next Best Thing | - | - | - | $48,028 | 2,035 | $14,990,582 | 0.3% | Mar 3, 2000 | Paramount Pictures |
| 70 | Island of the Sharks | - | - | - | $40,613 | 17 | $10,658,505 | 0.4% | Apr 23, 1999 | IMAX |
| 71 | The Filth and the Fury | - | - | - | $38,222 | 29 | $612,192 | 6.2% | Mar 29, 2000 | Fine Line Features |
| 72 | Committed | - | - | - | $22,355 | 13 | $40,361 | 55.4% | Apr 28, 2000 | Miramax |
| 73 | Coming Soon | - | - | - | $4,674 | 1 | $5,453 | 85.7% | May 12, 2000 | Unapix Entertainment Productions |
