| Rank
| Release
| Genre
| Budget
| Running Time
| Gross | Max Theaters | Total Gross | % of Total | Release Date | Distributor
|
|---|
| 1 | Crocodile Dundee II | - | - | - | $54,566,713 | 2,837 | $109,306,210 | 49.9% | May 25, 1988 | Paramount Pictures |
| 2 | Rambo III | - | - | - | $36,500,587 | 2,562 | $53,715,611 | 68% | May 25, 1988 | TriStar Pictures |
| 3 | Willow | - | - | - | $28,122,093 | 1,209 | $57,269,863 | 49.1% | May 20, 1988 | Metro-Goldwyn-Mayer (MGM) |
| 4 | Colors | - | - | - | $19,851,850 | 1,388 | $46,616,067 | 42.6% | Apr 15, 1988 | Orion Pictures |
| 5 | Friday the 13th: The New Blood | - | - | - | $17,617,543 | 1,796 | $19,170,001 | 91.9% | May 13, 1988 | Paramount Pictures |
| 6 | Beetlejuice | - | - | - | $16,870,548 | 1,582 | $73,707,461 | 22.9% | Mar 30, 1988 | Warner Bros. |
| 7 | Big | - | - | - | $14,315,281 | 1,419 | $114,968,774 | 12.5% | Jun 3, 1988 | Twentieth Century Fox |
| 8 | Moonstruck | - | - | - | $11,026,511 | 1,178 | $80,640,528 | 13.7% | Dec 18, 1987 | Metro-Goldwyn-Mayer (MGM) |
| 9 | Shakedown | - | - | - | $10,068,039 | 1,580 | $10,068,039 | 100% | May 6, 1988 | Universal Pictures |
| 10 | Funny Farm | - | - | - | $8,975,413 | 1,557 | $25,537,221 | 35.1% | Jun 3, 1988 | Warner Bros. |
| 11 | Salsa | - | - | - | $8,892,589 | 1,125 | $8,892,589 | 100% | May 6, 1988 | Cannon Film Distributors |
| 12 | Biloxi Blues | - | - | - | $8,475,588 | 1,330 | $43,184,798 | 19.6% | Mar 25, 1988 | Universal Pictures |
| 13 | The Last Emperor | - | - | - | $7,821,078 | 877 | $43,984,230 | 17.8% | Nov 20, 1987 | Columbia Pictures |
| 14 | The Milagro Beanfield War | - | - | - | $6,813,045 | 437 | $13,825,794 | 49.3% | Mar 18, 1988 | Universal Pictures |
| 15 | Above the Law | - | - | - | $6,342,384 | 868 | $18,869,631 | 33.6% | Apr 8, 1988 | Warner Bros. |
| 16 | Stand and Deliver | - | - | - | $5,871,438 | 472 | $13,994,920 | 42% | Mar 11, 1988 | Warner Bros. |
| 17 | Return to Snowy River | - | - | - | $5,028,081 | 1,121 | $13,687,027 | 36.7% | Apr 15, 1988 | Walt Disney Studios Motion Pictures |
| 18 | Three Men and a Baby | - | - | - | $4,337,129 | 1,813 | $167,780,960 | 2.6% | Nov 25, 1987 | Walt Disney Studios Motion Pictures |
| 19 | Casual Sex? | - | - | - | $4,228,945 | 1,265 | $12,277,096 | 34.4% | Apr 22, 1988 | Universal Pictures |
| 20 | Good Morning, Vietnam | - | - | - | $4,058,365 | 1,598 | $123,922,370 | 3.3% | Dec 25, 1987 | Walt Disney Studios Motion Pictures |
| 21 | Dead Heat | - | - | - | $3,588,626 | 1,012 | $3,588,626 | 100% | May 6, 1988 | New World Pictures |
| 22 | Dominick and Eugene | - | - | - | $2,673,966 | 76 | $3,076,031 | 86.9% | Mar 18, 1988 | Orion Pictures |
| 23 | The Manchurian Candidate 1988 Re-release | - | - | - | $2,643,053 | 49 | $2,757,256 | 95.9% | Feb 12, 1988 | Metro-Goldwyn-Mayer (MGM) |
| 24 | The Seventh Sign | - | - | - | $2,190,847 | 1,258 | $18,875,011 | 11.6% | Apr 1, 1988 | TriStar Pictures |
| 25 | Sunset | - | - | - | $2,036,441 | 1,024 | $4,594,452 | 44.3% | Apr 29, 1988 | TriStar Pictures |
| 26 | Stormy Monday | - | - | - | $1,729,498 | 49 | $1,791,328 | 96.5% | Apr 22, 1988 | Atlantic Releasing Corporation |
| 27 | Critters 2: The Main Course | - | - | - | $1,565,077 | 1,114 | $3,813,293 | 41% | Apr 29, 1988 | New Line Cinema |
| 28 | Lady in White | - | - | - | $1,347,110 | 107 | $1,705,139 | 79% | Apr 22, 1988 | New Century |
| 29 | The Unholy | - | - | - | $1,305,834 | 1,189 | $6,337,299 | 20.6% | Apr 22, 1988 | Vestron Pictures |
| 30 | Big Business | - | - | - | $1,302,435 | 1,232 | $40,150,487 | 3.2% | Jun 10, 1988 | Walt Disney Studios Motion Pictures |
| 31 | The Presidio | - | - | - | $1,039,522 | 1,168 | $20,324,096 | 5.1% | Jun 10, 1988 | Paramount Pictures |
| 32 | Aria | - | - | - | $1,018,105 | 34 | $1,028,679 | 99% | Mar 18, 1988 | Miramax |
| 33 | Poltergeist III | - | - | - | $867,357 | 1,471 | $14,114,488 | 6.1% | Jun 10, 1988 | Metro-Goldwyn-Mayer (MGM) |
| 34 | Bulletproof | - | - | - | $807,947 | 268 | $807,947 | 100% | May 13, 1988 | Universal Pictures |
| 35 | Two Moon Junction | - | - | - | $759,195 | 458 | $1,547,397 | 49.1% | Apr 29, 1988 | Lorimar Motion Pictures |
| 36 | Maniac Cop | - | - | - | $671,382 | 50 | $671,382 | 100% | May 13, 1988 | - |
| 37 | Da | - | - | - | $627,078 | 1 | $644,532 | 97.3% | Apr 29, 1988 | - |
| 38 | Powaqqatsi | - | - | - | $548,045 | 22 | $589,244 | 93% | Apr 29, 1988 | Cannon Film Distributors |
| 39 | The Decline of Western Civilization Part II: The Metal Years | - | - | - | $373,743 | 21 | $373,743 | 100% | Jun 3, 1988 | New Line Cinema |
| 40 | Prison | - | - | - | $345,704 | 42 | $345,704 | 100% | May 6, 1988 | New World Pictures |
| 41 | Judgment in Berlin | - | - | - | $229,556 | 81 | $229,556 | 100% | May 6, 1988 | New Line Cinema |
| 42 | A Time of Destiny | - | - | - | $225,667 | 220 | $1,212,487 | 18.6% | Apr 22, 1988 | Columbia Pictures |
| 43 | Beatrice | - | - | - | $193,983 | 8 | $211,821 | 91.6% | Mar 18, 1988 | The Samuel Goldwyn Company |
| 44 | My Best Friend Is a Vampire | - | - | - | $174,380 | 170 | $174,380 | 100% | May 6, 1988 | - |
| 45 | The Kitchen Toto | - | - | - | $101,807 | 4 | $101,807 | 100% | May 13, 1988 | Cannon Film Distributors |
| 46 | Consuming Passions | - | - | - | $95,694 | 5 | $118,206 | 81% | Apr 6, 1988 | The Samuel Goldwyn Company |
