| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 283 | T-Rex: Back to the Cretaceous | - | - | - | $9,035 | 38 | $53,354,743 | Oct 23 | IMAX | false |
| 130 | Galapagos | - | - | - | $271,083 | 14 | $18,630,372 | Oct 29 | IMAX | false |
| 216 | Haunted Castle | - | - | - | $36,552 | 10 | $13,651,656 | Feb 23 | - | false |
| 77 | Space Station 3D | - | - | - | $1,555,267 | 64 | $93,383,953 | Apr 19 | IMAX | false |
| 332 | A Grin Without A Cat | - | - | - | $1,550 | 1 | $43,616 | May 1 | Icarus Films | false |
| 189 | Wild Safari - A South African Adventure | - | - | - | $65,158 | 21 | $16,621,530 | Apr 8 | - | false |
| 71 | Magnificent Desolation: Walking on the Moon | - | - | - | $1,761,108 | 82 | $34,137,524 | Sep 23 | IMAX | false |
| 88 | Roving Mars | - | - | - | $969,069 | 27 | $10,407,978 | Jan 27 | Walt Disney Studios Motion Pictures | false |
| 83 | Deep Sea | - | - | - | $1,126,458 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 337 | El Topo | - | - | - | $901 | 4 | $80,302 | Dec 13 | ABKCO Films | false |
| 331 | The Holy Mountain | - | - | - | $1,561 | 3 | $61,001 | Jan 19 | ABKCO Films | false |
| 328 | El inmigrante | - | - | - | $1,711 | 2 | $15,100 | Jul 13 | Indican Pictures | false |
| 170 | A Man Named Pearl | - | - | - | $88,606 | 9 | $208,392 | Aug 31 | Tentmakers Entertainment | false |
| 325 | Forever | - | - | - | $1,938 | 1 | $31,502 | Sep 12 | Icarus Films | false |
| 48 | Sea Monsters: A Prehistoric Adventure | - | - | - | $6,445,643 | 252 | $23,746,066 | Oct 5 | National Geographic Entertainment | false |
| 195 | Bella | - | - | - | $57,342 | 457 | $8,070,537 | Oct 26 | Roadside Attractions | false |
| 255 | Holly | - | - | - | $15,769 | 11 | $166,620 | Nov 9 | Priority Films | false |
| 296 | The Sensation of Sight | - | - | - | $5,085 | 4 | $23,457 | Nov 9 | Monterey Media | false |
| 320 | Yiddish Theater: A Love Story | - | - | - | $2,299 | 3 | $40,182 | Nov 21 | New Love Films | false |
| 290 | Starting Out in the Evening | - | - | - | $6,266 | 43 | $898,786 | Nov 23 | Roadside Attractions | false |
| 267 | The Savages | - | - | - | $12,756 | 201 | $6,623,082 | Nov 28 | - | false |
| 174 | Juno | - | - | - | $84,926 | 2,534 | $143,495,265 | Dec 5 | - | false |
| 348 | The Violin | - | - | - | $452 | 3 | $65,298 | Dec 5 | Film Movement | false |
| 145 | The Singing Revolution | - | - | - | $182,017 | 5 | $426,855 | Dec 7 | Abramorama | false |
| 231 | Aida | - | - | - | $28,476 | 52 | $222,927 | Dec 9 | Emerging Pictures | false |
| 179 | Alvin and the Chipmunks | - | - | - | $78,182 | 3,499 | $217,326,974 | Dec 14 | Twentieth Century Fox | false |
| 264 | Shotgun Stories | - | - | - | $12,889 | 4 | $46,026 | Dec 14 | International Film Circuit | false |
| 109 | National Treasure: Book of Secrets | - | - | - | $583,176 | 3,832 | $219,964,115 | Dec 21 | Walt Disney Studios Motion Pictures | false |
| 113 | The Bucket List | - | - | - | $526,403 | 2,915 | $93,466,502 | Dec 25 | Warner Bros. | false |
| 223 | Persepolis | - | - | - | $32,613 | 536 | $4,445,756 | Dec 25 | Sony Pictures Classics | false |
| 294 | Honeydripper | - | - | - | $5,207 | 26 | $267,880 | Dec 28 | Emerging Pictures | false |
| 303 | Woman on the Beach 2008 Re-release | - | - | - | $4,341 | 1 | $23,686 | Jan 9 | New Yorker Films | false |
| 306 | Times and Winds | - | - | - | $4,132 | 2 | $6,176 | Jan 11 | Kino International | false |
| 177 | 27 Dresses | - | - | - | $81,129 | 3,074 | $76,808,654 | Jan 18 | Twentieth Century Fox | false |
| 234 | Last Year at Marienbad | - | - | - | $27,048 | 2 | $144,492 | Jan 18 | Rialto Pictures | false |
| 257 | Tristan und Isolde, Azione in tre atti | - | - | - | $15,590 | 6 | $50,172 | Jan 18 | Emerging Pictures | false |
| 260 | Taxi to the Dark Side | - | - | - | $13,534 | 20 | $274,661 | Jan 18 | THINKFilm | false |
| 261 | Mad Money | - | - | - | $13,369 | 2,470 | $20,668,843 | Jan 18 | Overture Films | false |
| 289 | Beaufort | - | - | - | $6,572 | 6 | $102,591 | Jan 18 | Kino International | false |
| 291 | Still Life | - | - | - | $6,077 | 2 | $76,983 | Jan 18 | New Yorker Films | false |
| 313 | Teeth | - | - | - | $3,005 | 16 | $347,578 | Jan 18 | Roadside Attractions | false |
| 72 | U2 3D | - | - | - | $1,728,039 | 686 | $10,363,341 | Jan 23 | National Geographic Entertainment | false |
| 246 | 4 Months, 3 Weeks and 2 Days | - | - | - | $18,267 | 47 | $1,198,208 | Jan 25 | IFC Films | false |
| 168 | Caramel | - | - | - | $97,298 | 50 | $1,055,580 | Feb 1 | Roadside Attractions | false |
| 248 | Hannah Montana and Miley Cyrus: Best of Both Worlds Concert | - | - | - | $17,513 | 687 | $65,281,781 | Feb 1 | Walt Disney Studios Motion Pictures | false |
| 279 | Praying with Lior | - | - | - | $10,271 | 4 | $82,553 | Feb 1 | First Run | false |
| 298 | The Witnesses | - | - | - | $4,745 | 6 | $78,440 | Feb 1 | Strand Releasing | false |
| 112 | Fool's Gold | - | - | - | $533,918 | 3,125 | $70,231,041 | Feb 8 | Warner Bros. | false |
| 124 | In Bruges | - | - | - | $367,577 | 232 | $7,800,824 | Feb 8 | Focus Features | false |
| 138 | The Band's Visit | - | - | - | $231,224 | 121 | $3,054,457 | Feb 8 | Sony Pictures Classics | false |
| 230 | Bab'Aziz: The Prince That Contemplated His Soul | - | - | - | $29,008 | 2 | $89,672 | Feb 8 | Typecast Releasing | false |
| 98 | Jumper | - | - | - | $792,519 | 3,430 | $80,172,128 | Feb 14 | Twentieth Century Fox | false |
| 132 | The Spiderwick Chronicles | - | - | - | $258,718 | 3,847 | $71,195,053 | Feb 14 | Paramount Pictures | false |
| 152 | Step Up 2: The Streets | - | - | - | $156,274 | 2,528 | $58,017,783 | Feb 14 | Walt Disney Studios Motion Pictures | false |
| 60 | Dolphins and Whales 3D: Tribes of the Ocean | - | - | - | $3,114,622 | 42 | $7,714,996 | Feb 15 | 3D Entertainment | false |
| 157 | The Year My Parents Went on Vacation | - | - | - | $128,704 | 30 | $807,117 | Feb 15 | City Lights Pictures | false |
| 217 | La Traviata | - | - | - | $36,140 | 49 | $195,494 | Feb 15 | Emerging Pictures | false |
| 81 | The Counterfeiters | - | - | - | $1,252,566 | 170 | $5,488,570 | Feb 22 | Sony Pictures Classics | false |
| 188 | The Duchess of Langeais | - | - | - | $65,659 | 11 | $282,749 | Feb 22 | IFC Films | false |
| 341 | Charlie Bartlett | - | - | - | $715 | 1,122 | $3,951,699 | Feb 22 | Metro-Goldwyn-Mayer (MGM) | false |
| 333 | I Can No Longer Hear the Guitar | - | - | - | $1,366 | 1 | $12,876 | Feb 25 | The Film Desk | false |
| 209 | Chop Shop | - | - | - | $42,935 | 3 | $125,045 | Feb 27 | Koch Lorber Films | false |
| 178 | Penelope | - | - | - | $80,230 | 1,207 | $10,011,996 | Feb 29 | Summit Entertainment | false |
| 235 | The Unforeseen | - | - | - | $26,209 | 3 | $90,287 | Feb 29 | The Cinema Guild | false |
| 275 | Chicago 10 | - | - | - | $10,863 | 14 | $177,490 | Feb 29 | Roadside Attractions | false |
| 338 | A Lawyer Walks Into a Bar... | - | - | - | $896 | 1 | $5,202 | Feb 29 | Indican Pictures | false |
| 350 | Vivere | - | - | - | $174 | 2 | $3,625 | Feb 29 | Regent Releasing | false |
| 266 | Box Elder | - | - | - | $12,775 | 2 | $48,996 | Mar 3 | - | false |
| 245 | Blindsight | - | - | - | $18,917 | 5 | $89,169 | Mar 5 | Abramorama | false |
| 65 | College Road Trip | - | - | - | $2,245,398 | 2,706 | $45,610,425 | Mar 7 | Walt Disney Studios Motion Pictures | false |
| 80 | 10,000 BC | - | - | - | $1,292,082 | 3,454 | $94,784,201 | Mar 7 | Warner Bros. | false |
| 123 | The Bank Job | - | - | - | $388,998 | 1,613 | $30,060,660 | Mar 7 | Lionsgate Films | false |
| 137 | Miss Pettigrew Lives for a Day | - | - | - | $233,248 | 539 | $12,313,694 | Mar 7 | Focus Features | false |
| 158 | Married Life | - | - | - | $122,395 | 120 | $1,507,990 | Mar 7 | Sony Pictures Classics | false |
| 212 | Girls Rock! | - | - | - | $39,574 | 14 | $159,294 | Mar 7 | Shadow Distribution | false |
| 224 | Paranoid Park | - | - | - | $31,393 | 37 | $486,767 | Mar 7 | IFC Films | false |
| 242 | Snow Angels | - | - | - | $20,594 | 47 | $402,858 | Mar 7 | Warner Independent Pictures (WIP) | false |
| 310 | Body of War | - | - | - | $3,442 | 5 | $71,716 | Mar 7 | - | false |
| 327 | CJ7 | - | - | - | $1,755 | 30 | $207,378 | Mar 7 | Sony Pictures Classics | false |
| 334 | Blind Mountain | - | - | - | $1,345 | 2 | $13,164 | Mar 12 | Kino International | false |
| 49 | Horton Hears a Who! | - | - | - | $6,047,148 | 3,961 | $154,529,439 | Mar 14 | Twentieth Century Fox | false |
| 121 | Never Back Down | - | - | - | $427,304 | 2,729 | $24,850,922 | Mar 14 | Summit Entertainment | false |
| 201 | Contempt 2008 Re-release | - | - | - | $53,162 | 2 | $153,619 | Mar 14 | Rialto Pictures | false |
| 211 | Maria Stuarda at La Scala | - | - | - | $40,925 | 43 | $83,214 | Mar 14 | Emerging Pictures | false |
| 236 | Monsieur Verdoux | - | - | - | $25,314 | 2 | $64,636 | Mar 14 | The Film Desk | false |
| 302 | Sleepwalking | - | - | - | $4,366 | 69 | $170,392 | Mar 14 | Overture Films | false |
| 103 | Under the Same Moon | - | - | - | $680,457 | 454 | $12,590,147 | Mar 19 | The Weinstein Company | false |
| 63 | Drillbit Taylor | - | - | - | $2,427,447 | 3,061 | $32,862,104 | Mar 21 | Paramount Pictures | false |
| 129 | Shutter | - | - | - | $278,971 | 2,756 | $25,928,550 | Mar 21 | Twentieth Century Fox | false |
| 144 | Meet the Browns | - | - | - | $184,502 | 2,016 | $41,975,388 | Mar 21 | Lionsgate Films | false |
| 220 | Love Songs | - | - | - | $34,326 | 7 | $104,567 | Mar 21 | IFC Films | false |
| 232 | Planet B-Boy | - | - | - | $27,709 | 14 | $273,870 | Mar 21 | Elephant Eye Films | false |
| 269 | Irina Palm | - | - | - | $12,312 | 4 | $44,383 | Mar 21 | Strand Releasing | false |
| 282 | Shelter | - | - | - | $9,177 | 10 | $142,666 | Mar 21 | Regent Releasing | false |
| 304 | The Hammer | - | - | - | $4,235 | 34 | $443,591 | Mar 21 | International Film Circuit | false |
| 336 | Poisoned by Polonium: The Litvinenko File | - | - | - | $944 | 1 | $5,080 | Mar 21 | Kino International | false |
| 349 | The Grand | - | - | - | $326 | 14 | $115,879 | Mar 21 | Anchor Bay Films | false |
| 183 | Alexandra | - | - | - | $72,594 | 4 | $128,222 | Mar 26 | The Cinema Guild | false |
| 54 | 21 | - | - | - | $4,202,599 | 2,952 | $81,159,365 | Mar 28 | Sony Pictures Releasing | false |
| 96 | Superhero Movie | - | - | - | $813,162 | 2,965 | $25,881,068 | Mar 28 | - | false |
| 126 | Flawless | - | - | - | $338,962 | 65 | $1,200,234 | Mar 28 | Magnolia Pictures | false |
| 154 | My Brother is an Only Child | - | - | - | $153,438 | 14 | $255,620 | Mar 28 | THINKFilm | false |
| 167 | Stop-Loss | - | - | - | $98,148 | 1,305 | $10,915,744 | Mar 28 | Paramount Pictures | false |
| 197 | Run Fatboy Run | - | - | - | $56,633 | 1,133 | $6,003,262 | Mar 28 | Picturehouse | false |
| 213 | A Four Letter Word | - | - | - | $38,507 | 5 | $72,568 | Mar 28 | Embrem Entertainment | false |
| 297 | Hats Off | - | - | - | $4,751 | 5 | $31,272 | Mar 28 | Abramorama | false |
| 343 | Happy Valley | - | - | - | $623 | 7 | $67,665 | Mar 28 | Stone Five Studios | false |
| 345 | Chapter 27 | - | - | - | $511 | 11 | $56,215 | Mar 28 | - | false |
| 87 | Priceless | - | - | - | $1,008,694 | 44 | $2,165,188 | Mar 30 | The Samuel Goldwyn Company | false |
| 287 | La forza del destino | - | - | - | $7,772 | 7 | $52,577 | Mar 31 | Emerging Pictures | false |
| 44 | Nim's Island | - | - | - | $8,212,645 | 3,518 | $48,006,762 | Apr 4 | Twentieth Century Fox | false |
| 75 | Leatherheads | - | - | - | $1,613,513 | 2,798 | $31,373,938 | Apr 4 | Universal Pictures | false |
| 89 | Shine a Light | - | - | - | $936,925 | 277 | $5,505,267 | Apr 4 | Paramount Vantage | false |
| 107 | The Ruins | - | - | - | $635,391 | 2,814 | $17,432,844 | Apr 4 | DreamWorks | false |
| 119 | My Blueberry Nights | - | - | - | $441,931 | 69 | $867,275 | Apr 4 | The Weinstein Company | false |
| 133 | Flight of the Red Balloon | - | - | - | $254,574 | 14 | $461,674 | Apr 4 | IFC Films | false |
| 135 | Jellyfish | - | - | - | $243,254 | 14 | $341,221 | Apr 4 | Zeitgeist Films | false |
| 192 | Water Lilies | - | - | - | $63,058 | 3 | $85,440 | Apr 4 | Koch Lorber Films | false |
| 200 | Tuya's Marriage | - | - | - | $54,228 | 5 | $88,148 | Apr 4 | Music Box Films | false |
| 58 | Young@Heart | - | - | - | $3,321,250 | 212 | $3,992,189 | Apr 9 | - | false |
| 43 | The Visitor | - | - | - | $8,360,845 | 270 | $9,427,089 | Apr 11 | Overture Films | false |
| 53 | Prom Night | - | - | - | $4,921,932 | 2,821 | $43,869,350 | Apr 11 | Screen Gems | false |
| 68 | Street Kings | - | - | - | $1,993,482 | 2,469 | $26,418,667 | Apr 11 | - | false |
| 92 | Smart People | - | - | - | $893,099 | 1,119 | $9,511,289 | Apr 11 | Miramax | false |
| 117 | Emma Smith: My Story | - | - | - | $456,682 | 42 | $881,787 | Apr 11 | Candlelight Media Group | false |
| 206 | Bra Boys | - | - | - | $47,413 | 23 | $155,056 | Apr 11 | Slowhand Cinema Releasing | false |
| 218 | The Dhamma Brothers | - | - | - | $34,980 | 3 | $40,492 | Apr 11 | Balcony Releasing | false |
| 219 | Refusenik | - | - | - | $34,419 | 3 | $39,456 | Apr 11 | Abramorama | false |
| 284 | Dark Matter | - | - | - | $8,881 | 5 | $30,591 | Apr 11 | First Independent Pictures | false |
| 311 | Never Forever | - | - | - | $3,139 | 2 | $14,485 | Apr 11 | Hart Sharp Entertainment | false |
| 33 | Forgetting Sarah Marshall | - | - | - | $24,500,043 | 2,872 | $63,172,463 | Apr 18 | Universal Pictures | false |
| 42 | The Forbidden Kingdom | - | - | - | $11,150,864 | 3,151 | $52,075,270 | Apr 18 | Lionsgate Films | false |
| 57 | 88 Minutes | - | - | - | $3,389,626 | 2,168 | $17,213,467 | Apr 18 | Sony Pictures Releasing | false |
| 73 | Expelled: No Intelligence Allowed | - | - | - | $1,709,744 | 1,052 | $7,720,487 | Apr 18 | Rocky Mountain Pictures | false |
| 147 | The Life Before Her Eyes | - | - | - | $178,284 | 48 | $303,439 | Apr 18 | Magnolia Pictures | false |
| 156 | Constantine's Sword | - | - | - | $136,409 | 6 | $179,507 | Apr 18 | First Run | false |
| 166 | Where in the World Is Osama Bin Laden? | - | - | - | $98,548 | 102 | $384,955 | Apr 18 | The Weinstein Company | false |
| 254 | The First Saturday in May | - | - | - | $16,289 | 20 | $124,294 | Apr 18 | Truly Indie | false |
| 256 | Kiss the Bride | - | - | - | $15,661 | 5 | $32,033 | Apr 18 | Regent Releasing | false |
| 315 | Glass | - | - | - | $2,821 | 1 | $20,018 | Apr 18 | Koch Lorber Films | false |
| 323 | Anamorph | - | - | - | $2,048 | 1 | $6,950 | Apr 18 | IFC Films | false |
| 324 | Pathology | - | - | - | $1,971 | 46 | $109,846 | Apr 18 | Metro-Goldwyn-Mayer (MGM) | false |
| 26 | Baby Mama | - | - | - | $38,496,742 | 2,627 | $60,494,212 | Apr 25 | Universal Pictures | false |
| 35 | Harold & Kumar Escape from Guantanamo Bay | - | - | - | $18,853,764 | 2,545 | $38,108,728 | Apr 25 | Warner Bros. | false |
| 56 | Then She Found Me | - | - | - | $3,612,140 | 153 | $3,735,717 | Apr 25 | THINKFilm | false |
| 76 | Roman de gare | - | - | - | $1,584,366 | 38 | $1,852,764 | Apr 25 | The Samuel Goldwyn Company | false |
| 78 | Deception | - | - | - | $1,481,269 | 2,001 | $4,598,506 | Apr 25 | Twentieth Century Fox | false |
| 101 | Up the Yangtze | - | - | - | $697,293 | 23 | $783,969 | Apr 25 | Zeitgeist Films | false |
| 141 | Standard Operating Procedure | - | - | - | $206,914 | 21 | $229,117 | Apr 25 | Sony Pictures Classics | false |
| 171 | Tashan | - | - | - | $86,647 | 75 | $457,380 | Apr 25 | Yash Raj Films | false |
| 249 | Dare Not Walk Alone | - | - | - | $17,494 | 3 | $52,166 | Apr 25 | Indican Pictures | false |
| 265 | The Cry | - | - | - | $12,776 | 6 | $21,427 | Apr 25 | Monterey Media | false |
| 277 | Deal | - | - | - | $10,372 | 51 | $61,626 | Apr 25 | Metro-Goldwyn-Mayer (MGM) | false |
| 312 | Without the King | - | - | - | $3,024 | 1 | $8,663 | Apr 25 | First Run | false |
| 3 | Iron Man | - | - | - | $314,347,676 | 4,154 | $318,604,126 | May 2 | Paramount Pictures | false |
| 23 | Made of Honor | - | - | - | $46,012,734 | 2,816 | $46,012,734 | May 2 | Sony Pictures Releasing | false |
| 64 | Redbelt | - | - | - | $2,344,038 | 1,379 | $2,345,941 | May 2 | Sony Pictures Classics | false |
| 70 | Son of Rambow | - | - | - | $1,785,505 | 155 | $1,785,505 | May 2 | Paramount Vantage | false |
| 106 | Fugitive Pieces | - | - | - | $635,783 | 38 | $635,783 | May 2 | The Samuel Goldwyn Company | false |
| 148 | Mister Lonely | - | - | - | $167,396 | 8 | $167,396 | May 2 | IFC Films | false |
| 182 | Il trittico dell'amore | - | - | - | $76,128 | 43 | $80,374 | May 2 | Emerging Pictures | false |
| 208 | Love and Honor | - | - | - | $43,686 | 3 | $60,910 | May 2 | Eleven Arts | false |
| 214 | XXY | - | - | - | $38,224 | 2 | $48,334 | May 2 | Film Movement | false |
| 280 | As It Is in Heaven 2008 Re-release | - | - | - | $10,236 | 1 | $10,236 | May 2 | Vitagraph Films | false |
| 281 | As Tears Go By | - | - | - | $9,436 | 1 | $9,436 | May 2 | Kino International | false |
| 335 | Kiss Me Deadly | - | - | - | $1,085 | 2 | $1,085 | May 2 | Regent Releasing | false |
| 278 | Battle for Haditha | - | - | - | $10,310 | 2 | $10,310 | May 7 | Lafayette Films | false |
| 19 | What Happens in Vegas | - | - | - | $80,264,990 | 3,255 | $80,277,646 | May 9 | Twentieth Century Fox | false |
| 24 | Speed Racer | - | - | - | $43,945,766 | 3,606 | $43,945,766 | May 9 | Warner Bros. | false |
| 66 | The Fall | - | - | - | $2,242,202 | 111 | $2,266,905 | May 9 | Roadside Attractions | false |
| 85 | Before the Rains | - | - | - | $1,018,430 | 44 | $1,029,655 | May 9 | Roadside Attractions | false |
| 115 | Bhoothnath | - | - | - | $476,032 | 64 | $476,032 | May 9 | Eros Worldwide | false |
| 128 | OSS 117: Cairo, Nest of Spies | - | - | - | $289,049 | 13 | $303,543 | May 9 | Music Box Films | false |
| 131 | Surfwise | - | - | - | $269,994 | 13 | $269,994 | May 9 | Magnolia Pictures | false |
| 190 | Bloodline | - | - | - | $64,698 | 5 | $64,698 | May 9 | Cinema Libre Studio | false |
| 202 | America the Beautiful | - | - | - | $51,049 | 5 | $76,173 | May 9 | First Independent Pictures | false |
| 207 | The Babysitters | - | - | - | $44,852 | 22 | $44,852 | May 9 | - | false |
| 222 | The Tracey Fragments | - | - | - | $32,645 | 4 | $32,645 | May 9 | THINKFilm | false |
| 252 | Noise | - | - | - | $16,513 | 2 | $16,513 | May 9 | THINKFilm | false |
| 258 | Poultrygeist: Night of the Chicken Dead | - | - | - | $13,804 | 1 | $13,804 | May 9 | Troma | false |
| 295 | Turn the River | - | - | - | $5,149 | 2 | $5,149 | May 9 | Screen Media Films | false |
| 330 | House of Usher | - | - | - | $1,677 | 2 | $1,677 | May 9 | Regent Releasing | false |
| 198 | Blood of My Blood | - | - | - | $55,730 | 7 | $55,730 | May 14 | IFC Films | false |
| 8 | The Chronicles of Narnia: Prince Caspian | - | - | - | $141,591,075 | 3,929 | $141,621,490 | May 16 | Walt Disney Studios Motion Pictures | false |
| 111 | Reprise | - | - | - | $554,826 | 15 | $554,826 | May 16 | Miramax | false |
| 153 | My Father My Lord | - | - | - | $154,947 | 9 | $203,708 | May 16 | Kino International | false |
| 239 | Yella | - | - | - | $23,255 | 2 | $30,647 | May 16 | The Cinema Guild | false |
| 139 | How the Garcia Girls Spent Their Summer | - | - | - | $215,303 | 84 | $215,303 | May 18 | Maya Entertainment | false |
| 199 | La Rondine | - | - | - | $54,625 | 5 | $49,088 | May 19 | Emerging Pictures | false |
| 104 | The Edge of Heaven | - | - | - | $673,206 | 20 | $742,349 | May 21 | Strand Releasing | false |
| 173 | A Jihad for Love | - | - | - | $85,063 | 5 | $105,651 | May 21 | First Run | false |
| 2 | Indiana Jones and the Kingdom of the Crystal Skull | - | - | - | $315,844,754 | 4,264 | $317,101,119 | May 22 | Paramount Pictures | false |
| 95 | The Children of Huang Shi | - | - | - | $828,285 | 43 | $1,031,872 | May 23 | Sony Pictures Classics | false |
| 110 | War, Inc. | - | - | - | $580,862 | 33 | $580,862 | May 23 | First Look International | false |
| 305 | Twisted: A Balloonamentary | - | - | - | $4,218 | 2 | $4,218 | May 23 | - | false |
| 308 | Heavy Metal in Baghdad | - | - | - | $4,070 | 2 | $4,070 | May 23 | Hart Sharp Entertainment | false |
| 120 | Savage Grace | - | - | - | $435,746 | 22 | $435,746 | May 28 | IFC Films | false |
| 7 | Sex and the City | - | - | - | $152,525,242 | 3,325 | $152,647,258 | May 30 | Warner Bros. | false |
| 22 | The Strangers | - | - | - | $52,597,610 | 2,477 | $52,597,610 | May 30 | Rogue Pictures | false |
| 127 | Bigger Stronger Faster* | - | - | - | $308,575 | 26 | $308,575 | May 30 | Magnolia Pictures | false |
