| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 237 | Galapagos | - | - | - | $1,025 | 14 | $18,630,372 | Oct 29 | IMAX | false |
| 85 | Space Station 3D | - | - | - | $285,468 | 64 | $93,383,953 | Apr 19 | IMAX | false |
| 131 | Magnificent Desolation: Walking on the Moon | - | - | - | $51,095 | 82 | $34,137,524 | Sep 23 | IMAX | false |
| 110 | Deep Sea | - | - | - | $115,394 | 47 | $46,412,757 | Mar 3 | Warner Bros. | false |
| 120 | Sea Monsters: A Prehistoric Adventure | - | - | - | $82,594 | 252 | $23,746,066 | Oct 5 | National Geographic Entertainment | false |
| 247 | Monsieur Verdoux | - | - | - | $420 | 2 | $64,636 | Mar 14 | The Film Desk | false |
| 71 | Under the Sea 3D | - | - | - | $559,729 | 108 | $36,262,926 | Feb 13 | Warner Bros. | false |
| 243 | Le combat dans l'île | - | - | - | $619 | 1 | $50,039 | Jun 12 | The Film Desk | false |
| 239 | Mississippi Mermaid | - | - | - | $964 | 1 | $33,216 | Jul 10 | The Film Desk | false |
| 206 | Patrik, Age 1.5 | - | - | - | $4,590 | 9 | $57,468 | Aug 14 | Regent Releasing | false |
| 241 | Small Change | - | - | - | $889 | 2 | $38,296 | Nov 24 | The Film Desk | false |
| 250 | Home | - | - | - | $248 | 2 | $15,925 | Nov 27 | Lorber Films | false |
| 235 | Sweetgrass | - | - | - | $1,254 | 9 | $207,473 | Jan 6 | The Cinema Guild | false |
| 218 | Brutal Beauty: Tales of the Rose City Rollers | - | - | - | $2,520 | 2 | $9,677 | Jan 8 | Cinema Purgatorio | false |
| 167 | House | - | - | - | $14,003 | 7 | $209,765 | Jan 15 | Janus Films | false |
| 223 | The Girl on the Train | - | - | - | $2,102 | 10 | $208,023 | Jan 22 | Strand Releasing | false |
| 244 | Ajami | - | - | - | $544 | 23 | $622,403 | Feb 3 | Kino International | false |
| 205 | Ran 2010 Re-release | - | - | - | $4,687 | 4 | $124,673 | Feb 5 | Rialto Pictures | false |
| 249 | Promised Lands | - | - | - | $250 | 1 | $4,546 | Feb 5 | The Film Desk | false |
| 246 | Prodigal Sons | - | - | - | $460 | 11 | $73,544 | Feb 26 | First Run | false |
| 234 | The Harimaya Bridge | - | - | - | $1,338 | 3 | $54,473 | Mar 12 | Eleven Arts | false |
| 217 | Mid-August Lunch | - | - | - | $2,532 | 23 | $675,299 | Mar 17 | Zeitgeist Films | false |
| 44 | Hubble | - | - | - | $2,442,060 | 151 | $52,522,904 | Mar 19 | Warner Bros. | false |
| 125 | The Girl with the Dragon Tattoo | - | - | - | $69,912 | 202 | $10,095,170 | Mar 19 | Music Box Films | false |
| 155 | See What I'm Saying: The Deaf Entertainers Documentary | - | - | - | $22,867 | 21 | $118,206 | Mar 19 | Worldplay | false |
| 245 | The Flower of Kim Jong II | - | - | - | $498 | 1 | $4,362 | Mar 19 | Lorber Films | false |
| 145 | 2012: Time for Change | - | - | - | $32,833 | 2 | $68,339 | Apr 9 | Mangusta Productions | false |
| 154 | The Cremaster Cycle 2010 Re-release | - | - | - | $22,886 | 2 | $151,239 | Apr 9 | International Film Circuit | false |
| 188 | Everyone Else | - | - | - | $7,220 | 5 | $102,042 | Apr 9 | The Cinema Guild | false |
| 215 | Date Night | - | - | - | $3,066 | 3,380 | $98,711,404 | Apr 9 | Twentieth Century Fox | false |
| 227 | Fresh | - | - | - | $1,719 | 3 | $25,115 | Apr 9 | - | false |
| 123 | Exit Through the Gift Shop | - | - | - | $75,407 | 46 | $3,291,250 | Apr 16 | - | false |
| 135 | The Secret in Their Eyes | - | - | - | $44,653 | 166 | $6,391,436 | Apr 16 | Sony Pictures Classics | false |
| 157 | Feed the Fish | - | - | - | $20,754 | 4 | $101,170 | Apr 23 | Strand Releasing | false |
| 185 | Best Worst Movie | - | - | - | $8,060 | 2 | $109,895 | Apr 23 | Abramorama | false |
| 233 | Behind the Burly Q | - | - | - | $1,342 | 2 | $23,889 | Apr 23 | First Run | false |
| 174 | Please Give | - | - | - | $12,667 | 272 | $4,033,574 | Apr 30 | Sony Pictures Classics | false |
| 105 | Metropolis 2010 Re-release | - | - | - | $144,950 | 9 | $529,603 | May 7 | Kino International | false |
| 181 | Mother and Child | - | - | - | $10,456 | 119 | $1,110,509 | May 7 | Sony Pictures Classics | false |
| 187 | Princess Kaiulani | - | - | - | $7,583 | 47 | $883,887 | May 14 | Roadside Attractions | false |
| 253 | Here and There | - | - | - | $78 | 5 | $27,156 | May 14 | Cinema Purgatorio | false |
| 238 | Two in the Wave | - | - | - | $1,001 | 1 | $28,808 | May 19 | Lorber Films | false |
| 82 | Shrek Forever After | - | - | - | $364,800 | 4,386 | $238,736,787 | May 21 | DreamWorks | false |
| 159 | Solitary Man | - | - | - | $20,412 | 177 | $4,360,548 | May 21 | Anchor Bay Films | false |
| 180 | John Rabe | - | - | - | $10,948 | 6 | $67,519 | May 21 | Strand Releasing | false |
| 96 | Mademoiselle Chambon | - | - | - | $187,215 | 16 | $531,685 | May 28 | Lorber Films | false |
| 122 | Prince of Persia: The Sands of Time | - | - | - | $81,315 | 3,646 | $90,759,676 | May 28 | Walt Disney Studios Motion Pictures | false |
| 128 | Micmacs | - | - | - | $54,879 | 52 | $1,262,079 | May 28 | Sony Pictures Classics | false |
| 130 | Breathless 2010 Re-release | - | - | - | $51,673 | 12 | $363,031 | May 28 | Rialto Pictures | false |
| 134 | Agora | - | - | - | $45,666 | 17 | $619,423 | May 28 | Newmarket Films | false |
| 230 | Double Take | - | - | - | $1,517 | 1 | $20,218 | Jun 2 | Kino International | false |
| 164 | Marmaduke | - | - | - | $14,441 | 3,213 | $33,644,788 | Jun 4 | Twentieth Century Fox | false |
| 179 | Ondine | - | - | - | $11,119 | 39 | $550,472 | Jun 4 | Magnolia Pictures | false |
| 200 | Cropsey | - | - | - | $5,289 | 4 | $52,476 | Jun 4 | Cinema Purgatorio | false |
| 226 | Rosencrantz and Guildenstern Are Undead | - | - | - | $1,800 | 4 | $71,007 | Jun 4 | Indican Pictures | false |
| 70 | Winter's Bone | - | - | - | $573,936 | 141 | $6,531,503 | Jun 11 | Roadside Attractions | false |
| 81 | The Karate Kid | - | - | - | $401,215 | 3,740 | $176,591,618 | Jun 11 | Sony Pictures Releasing | false |
| 113 | Coco Chanel & Igor Stravinsky | - | - | - | $106,234 | 74 | $1,621,226 | Jun 11 | Sony Pictures Classics | false |
| 141 | The A-Team | - | - | - | $34,765 | 3,544 | $77,222,099 | Jun 11 | Twentieth Century Fox | false |
| 176 | Joan Rivers: A Piece of Work | - | - | - | $12,121 | 115 | $2,930,687 | Jun 11 | IFC Films | false |
| 252 | Kings of the Evening | - | - | - | $147 | 5 | $99,270 | Jun 11 | Indican Pictures | false |
| 192 | Stonewall Uprising | - | - | - | $6,812 | 10 | $128,203 | Jun 16 | First Run | false |
| 33 | Toy Story 3 | - | - | - | $5,135,313 | 4,028 | $415,004,880 | Jun 18 | Walt Disney Studios Motion Pictures | false |
| 84 | I Am Love | - | - | - | $321,431 | 166 | $5,005,465 | Jun 18 | Magnolia Pictures | false |
| 116 | Cyrus | - | - | - | $87,828 | 454 | $7,468,936 | Jun 18 | - | false |
| 184 | The Nature of Existence | - | - | - | $8,137 | 4 | $54,645 | Jun 18 | Walking Shadows | false |
| 199 | The Girlfriends | - | - | - | $5,313 | 1 | $68,167 | Jun 18 | The Film Desk | false |
| 222 | American Grindhouse | - | - | - | $2,141 | 2 | $5,529 | Jun 18 | Lorber Films | false |
| 95 | Knight and Day 2010 Re-release | - | - | - | $191,296 | 3,104 | $76,423,035 | Jun 23 | Twentieth Century Fox | false |
| 48 | Grown Ups | - | - | - | $2,068,780 | 3,534 | $162,001,186 | Jun 25 | Sony Pictures Releasing | false |
| 104 | Restrepo | - | - | - | $153,663 | 52 | $1,330,894 | Jun 25 | National Geographic Entertainment | false |
| 137 | Wild Grass | - | - | - | $42,154 | 23 | $403,952 | Jun 25 | Sony Pictures Classics | false |
| 195 | Dogtooth | - | - | - | $6,673 | 5 | $110,248 | Jun 25 | Kino International | false |
| 51 | The Twilight Saga: Eclipse | - | - | - | $1,733,285 | 4,468 | $300,531,751 | Jun 30 | Summit Entertainment | false |
| 69 | The Last Airbender | - | - | - | $615,036 | 3,203 | $131,772,187 | Jul 1 | Paramount Pictures | false |
| 242 | Only When I Dance | - | - | - | $727 | 1 | $8,738 | Jul 2 | Film Movement | false |
| 29 | Despicable Me | - | - | - | $6,485,380 | 3,602 | $251,639,815 | Jul 9 | Universal Pictures | false |
| 60 | The Girl Who Played with Fire | - | - | - | $1,038,348 | 185 | $7,638,241 | Jul 9 | Music Box Films | false |
| 63 | The Kids Are All Right | - | - | - | $920,107 | 994 | $20,811,365 | Jul 9 | Focus Features | false |
| 90 | Predators | - | - | - | $211,855 | 2,669 | $52,000,688 | Jul 9 | Twentieth Century Fox | false |
| 136 | Winnebago Man | - | - | - | $42,307 | 12 | $181,039 | Jul 9 | Kino International | false |
| 209 | Around a Small Mountain | - | - | - | $3,701 | 3 | $33,216 | Jul 9 | The Cinema Guild | false |
| 52 | The Sorcerer's Apprentice | - | - | - | $1,584,824 | 3,504 | $63,150,991 | Jul 14 | Walt Disney Studios Motion Pictures | false |
| 172 | Alamar | - | - | - | $12,844 | 3 | $61,613 | Jul 14 | Film Movement | false |
| 21 | Inception | - | - | - | $12,673,305 | 3,792 | $292,576,195 | Jul 16 | Warner Bros. | false |
| 190 | Henri-Georges Clouzot's Inferno | - | - | - | $7,048 | 3 | $25,489 | Jul 16 | Flicker Alley | false |
| 139 | Jean-Michel Basquiat: The Radiant Child | - | - | - | $38,693 | 7 | $256,242 | Jul 21 | Arthouse Films | false |
| 41 | Salt | - | - | - | $2,749,706 | 3,612 | $118,311,368 | Jul 23 | Sony Pictures Releasing | false |
| 65 | Ramona and Beezus | - | - | - | $840,734 | 2,719 | $26,167,002 | Jul 23 | Twentieth Century Fox | false |
| 152 | Life During Wartime | - | - | - | $25,837 | 20 | $281,447 | Jul 23 | IFC Films | false |
| 162 | Countdown to Zero | - | - | - | $18,389 | 28 | $272,040 | Jul 23 | Magnolia Pictures | false |
| 193 | Spoken Word | - | - | - | $6,791 | 4 | $32,961 | Jul 23 | Variance Films | false |
| 221 | Orlando 2010 Re-release | - | - | - | $2,184 | 5 | $58,198 | Jul 23 | Sony Pictures Classics | false |
| 229 | Mugabe and the White African | - | - | - | $1,532 | 1 | $7,924 | Jul 23 | First Run | false |
| 35 | Get Low | - | - | - | $3,757,076 | 570 | $9,176,933 | Jul 30 | Sony Pictures Classics | false |
| 50 | Dinner for Schmucks | - | - | - | $1,859,521 | 3,046 | $73,026,337 | Jul 30 | DreamWorks | false |
| 54 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $1,376,430 | 3,705 | $43,585,753 | Jul 30 | Warner Bros. | false |
| 92 | The Concert | - | - | - | $200,008 | 21 | $657,986 | Jul 30 | The Weinstein Company | false |
| 101 | Charlie St. Cloud | - | - | - | $161,535 | 2,725 | $31,162,545 | Jul 30 | Universal Pictures | false |
| 119 | The Extra Man | - | - | - | $85,210 | 33 | $453,377 | Jul 30 | Magnolia Pictures | false |
| 168 | Enemies of the People | - | - | - | $13,767 | 6 | $73,171 | Jul 30 | International Film Circuit | false |
| 133 | The Sicilian Girl 2010 Re-release | - | - | - | $46,354 | 6 | $71,239 | Aug 4 | Music Box Films | false |
| 24 | The Other Guys | - | - | - | $10,722,500 | 3,651 | $119,219,978 | Aug 6 | Sony Pictures Releasing | false |
| 58 | Step Up 3D | - | - | - | $1,115,826 | 2,439 | $42,400,223 | Aug 6 | Walt Disney Studios Motion Pictures | false |
| 62 | Flipped | - | - | - | $985,076 | 442 | $1,755,212 | Aug 6 | Warner Bros. | false |
| 66 | Cairo Time | - | - | - | $761,915 | 76 | $1,603,616 | Aug 6 | IFC Films | false |
| 94 | The Wildest Dream | - | - | - | $192,689 | 21 | $898,137 | Aug 6 | National Geographic Entertainment | false |
| 98 | Lebanon | - | - | - | $168,538 | 23 | $368,088 | Aug 6 | Sony Pictures Classics | false |
| 161 | The Disappearance of Alice Creed | - | - | - | $19,683 | 12 | $166,980 | Aug 6 | Anchor Bay Films | false |
| 25 | Eat Pray Love | - | - | - | $10,294,366 | 3,108 | $80,574,010 | Aug 13 | Sony Pictures Releasing | false |
| 27 | The Expendables | - | - | - | $9,182,930 | 3,398 | $103,068,524 | Aug 13 | Lionsgate Films | false |
| 45 | Scott Pilgrim vs. the World | - | - | - | $2,257,145 | 2,820 | $31,524,275 | Aug 13 | Universal Pictures | false |
| 76 | Animal Kingdom | - | - | - | $443,173 | 61 | $1,044,039 | Aug 13 | Sony Pictures Classics | false |
| 132 | La soga | - | - | - | $48,793 | 20 | $210,625 | Aug 13 | 7-57 Releasing | false |
| 194 | Neshoba | - | - | - | $6,771 | 2 | $19,245 | Aug 13 | First Run | false |
| 214 | Peepli Live | - | - | - | $3,114 | 70 | $757,951 | Aug 13 | UTV Motion Pictures | false |
| 216 | The People I've Slept With | - | - | - | $2,973 | 2 | $19,137 | Aug 13 | - | false |
| 232 | Salt of This Sea 2010 Re-release | - | - | - | $1,365 | 2 | $11,662 | Aug 13 | Lorber Films | false |
| 37 | Vampires Suck | - | - | - | $3,408,995 | 3,233 | $36,661,504 | Aug 18 | Twentieth Century Fox | false |
| 102 | A Film Unfinished | - | - | - | $157,089 | 16 | $320,486 | Aug 18 | Oscilloscope | false |
| 31 | Nanny McPhee Returns | - | - | - | $5,338,555 | 2,798 | $29,011,215 | Aug 20 | Universal Pictures | false |
| 32 | The Switch | - | - | - | $5,287,564 | 2,017 | $27,779,426 | Aug 20 | Miramax | false |
| 36 | Lottery Ticket | - | - | - | $3,644,907 | 1,974 | $24,719,879 | Aug 20 | Warner Bros. | false |
| 40 | Mao's Last Dancer | - | - | - | $2,804,118 | 137 | $4,817,770 | Aug 20 | The Samuel Goldwyn Company | false |
| 49 | Piranha 3D | - | - | - | $1,887,598 | 2,491 | $25,003,155 | Aug 20 | - | false |
| 74 | The Tillman Story | - | - | - | $448,462 | 28 | $802,535 | Aug 20 | The Weinstein Company | false |
| 77 | What If... | - | - | - | $438,671 | 82 | $814,906 | Aug 20 | Five & Two Pictures | false |
| 100 | Soul Kitchen | - | - | - | $163,914 | 23 | $276,901 | Aug 20 | IFC Films | false |
| 186 | Army of Crime | - | - | - | $7,697 | 3 | $37,031 | Aug 20 | Lorber Films | false |
| 240 | Altiplano | - | - | - | $912 | 1 | $2,961 | Aug 20 | First Run | false |
| 17 | Takers | - | - | - | $17,429,517 | 2,206 | $57,744,720 | Aug 27 | Screen Gems | false |
| 28 | The Last Exorcism | - | - | - | $7,511,775 | 2,874 | $41,034,350 | Aug 27 | Lionsgate Films | false |
| 47 | Avatar 2010 Special Edition | - | - | - | $2,189,208 | 812 | $10,741,486 | Aug 27 | Twentieth Century Fox | false |
| 87 | The Salvation Poem | - | - | - | $270,928 | 30 | $914,818 | Aug 27 | CanZion Films | false |
| 89 | Mesrine: Killer Instinct 2010 Re-release | - | - | - | $212,988 | 34 | $551,697 | Aug 27 | Music Box Films | false |
| 142 | Centurion | - | - | - | $33,974 | 19 | $123,570 | Aug 27 | Magnolia Pictures | false |
| 169 | Le code a changé | - | - | - | $13,472 | 2 | $46,714 | Aug 27 | IFC Films | false |
| 202 | The Milk of Sorrow | - | - | - | $4,960 | 2 | $10,462 | Aug 27 | Olive Films | false |
| 211 | The Two Escobars | - | - | - | $3,514 | 1 | $14,457 | Aug 27 | All Rise Films | false |
| 212 | Circle | - | - | - | $3,416 | 2 | $10,024 | Aug 27 | Indican Pictures | false |
| 18 | The American | - | - | - | $15,800,258 | 2,833 | $35,606,376 | Sep 1 | Focus Features | false |
| 121 | My Dog Tulip | - | - | - | $81,698 | 5 | $246,574 | Sep 1 | New Yorker Films | false |
| 22 | Machete | - | - | - | $12,461,858 | 2,678 | $26,593,646 | Sep 3 | Twentieth Century Fox | false |
| 26 | Going the Distance | - | - | - | $9,296,009 | 3,030 | $17,804,299 | Sep 3 | Warner Bros. | false |
| 86 | We Are Family | - | - | - | $271,790 | 78 | $638,144 | Sep 3 | UTV Motion Pictures | false |
| 93 | Last Train Home | - | - | - | $195,148 | 14 | $288,328 | Sep 3 | Zeitgeist Films | false |
| 97 | Mesrine: Public Enemy No. 1 2010 Re-release | - | - | - | $177,544 | 31 | $275,387 | Sep 3 | Music Box Films | false |
| 103 | A Woman, a Gun and a Noodle Shop | - | - | - | $155,393 | 23 | $190,946 | Sep 3 | Sony Pictures Classics | false |
| 204 | White Wedding 2010 Re-release | - | - | - | $4,706 | 4 | $11,710 | Sep 3 | Dada Films | false |
| 6 | Resident Evil: Afterlife | - | - | - | $60,128,566 | 3,209 | $60,128,566 | Sep 10 | Screen Gems | false |
| 56 | Dabangg | - | - | - | $1,288,549 | 68 | $1,288,549 | Sep 10 | Eros Worldwide | false |
| 75 | Heartbreaker | - | - | - | $444,391 | 43 | $504,030 | Sep 10 | IFC Films | false |
| 79 | I'm Still Here | - | - | - | $408,983 | 120 | $408,983 | Sep 10 | Magnolia Pictures | false |
| 91 | Legendary | - | - | - | $200,393 | 177 | $200,393 | Sep 10 | The Samuel Goldwyn Company | false |
| 99 | Fool for Love | - | - | - | $164,319 | 8 | $165,987 | Sep 10 | Variance Films | false |
| 108 | Genius Within: The Inner Life of Glenn Gould | - | - | - | $122,443 | 9 | $167,508 | Sep 10 | Lorber Films | false |
| 109 | Lovely, Still | - | - | - | $119,829 | 17 | $127,564 | Sep 10 | Monterey Media | false |
| 111 | Bran Nue Dae | - | - | - | $113,568 | 55 | $113,568 | Sep 10 | Freestyle Releasing | false |
| 112 | The Romantics | - | - | - | $106,524 | 14 | $106,524 | Sep 10 | - | false |
| 144 | Ahead of Time: The Extraordinary Journey of Ruth Gruber | - | - | - | $33,024 | 3 | $33,024 | Sep 10 | Vitagraph Films | false |
| 149 | Who Is Harry Nilsson (And Why Is Everybody Talkin' About Him?) | - | - | - | $30,975 | 3 | $30,975 | Sep 10 | Lorber Films | false |
| 151 | Hideaway | - | - | - | $30,200 | 5 | $34,525 | Sep 10 | Strand Releasing | false |
| 160 | The Trial | - | - | - | $19,753 | 2 | $19,753 | Sep 10 | Mountain Top Releasing | false |
| 189 | Logan | - | - | - | $7,137 | 1 | $7,137 | Sep 10 | - | false |
| 198 | The Fall of Night | - | - | - | $5,673 | 7 | $5,673 | Sep 10 | - | false |
| 219 | The Afterlight | - | - | - | $2,339 | 1 | $3,059 | Sep 10 | Cinema Purgatorio | false |
| 46 | Never Let Me Go | - | - | - | $2,242,388 | 232 | $2,434,652 | Sep 15 | - | false |
| 107 | Kings of Pastry | - | - | - | $137,439 | 10 | $336,386 | Sep 15 | First Run | false |
| 150 | GasLand | - | - | - | $30,846 | 2 | $30,846 | Sep 15 | - | false |
| 210 | Metal Messiah | - | - | - | $3,563 | 1 | $3,476 | Sep 16 | - | false |
| 2 | The Town | - | - | - | $88,583,857 | 2,935 | $92,186,262 | Sep 17 | Warner Bros. | false |
| 7 | Easy A | - | - | - | $56,748,611 | 2,974 | $58,401,464 | Sep 17 | Screen Gems | false |
| 12 | Devil | - | - | - | $33,242,210 | 2,811 | $33,601,190 | Sep 17 | Universal Pictures | false |
| 16 | Alpha and Omega | - | - | - | $24,307,436 | 2,625 | $25,107,267 | Sep 17 | Lionsgate Films | false |
| 39 | Catfish | - | - | - | $3,101,448 | 143 | $3,237,343 | Sep 17 | Rogue Pictures | false |
| 72 | Jack Goes Boating | - | - | - | $478,782 | 90 | $541,992 | Sep 17 | Overture Films | false |
| 124 | Leaves of Grass | - | - | - | $70,066 | 6 | $70,066 | Sep 17 | First Look International | false |
| 138 | On the Bowery | - | - | - | $41,802 | 1 | $41,802 | Sep 17 | Milestone | false |
| 153 | Undertow | - | - | - | $23,783 | 3 | $108,620 | Sep 17 | The Film Collaborative | false |
| 156 | The Other City | - | - | - | $22,539 | 2 | $22,539 | Sep 17 | Cabin Films | false |
| 175 | The Freebie | - | - | - | $12,621 | 4 | $16,613 | Sep 17 | Phase 4 Films | false |
| 177 | Picture Me | - | - | - | $11,687 | 1 | $12,008 | Sep 17 | Strand Releasing | false |
| 207 | Sweethearts of the Prison Rodeo | - | - | - | $4,567 | 2 | $5,922 | Sep 17 | Cinema Purgatorio | false |
| 213 | El Superstar: The Unlikely Rise of Juan Frances | - | - | - | $3,271 | 1 | $3,271 | Sep 17 | Cinema Libre Studio | false |
| 220 | The Girl 2010 Re-release | - | - | - | $2,201 | 1 | $2,201 | Sep 17 | Olive Films | false |
| 225 | The Temptation of St. Tony | - | - | - | $1,963 | 1 | $1,963 | Sep 17 | Olive Films | false |
| 42 | You Will Meet a Tall Dark Stranger | - | - | - | $2,518,148 | 402 | $3,248,246 | Sep 22 | Sony Pictures Classics | false |
| 8 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $53,530,095 | 3,575 | $55,675,313 | Sep 24 | Warner Bros. | false |
| 9 | Wall Street: Money Never Sleeps | - | - | - | $51,554,290 | 3,597 | $52,474,616 | Sep 24 | Twentieth Century Fox | false |
| 14 | You Again | - | - | - | $24,888,960 | 2,548 | $25,702,053 | Sep 24 | Walt Disney Studios Motion Pictures | false |
| 34 | Waiting for Superman | - | - | - | $5,012,843 | 330 | $6,417,135 | Sep 24 | Paramount Vantage | false |
| 61 | Buried | - | - | - | $1,002,061 | 107 | $1,044,143 | Sep 24 | Lionsgate Films | false |
| 68 | The Virginity Hit | - | - | - | $636,706 | 700 | $636,706 | Sep 24 | Sony Pictures Releasing | false |
| 80 | Howl | - | - | - | $407,312 | 29 | $617,334 | Sep 24 | Oscilloscope | false |
| 83 | Like Dandelion Dust | - | - | - | $352,810 | 60 | $352,810 | Sep 24 | Blue Collar Releasing | false |
| 88 | Enter the Void | - | - | - | $239,493 | 13 | $336,467 | Sep 24 | IFC Films | false |
| 228 | A Mother's Courage: Talking Back to Autism 2010 Re-release | - | - | - | $1,604 | 2 | $1,916 | Sep 24 | First Run | false |
| 191 | Nine Nation Animation | - | - | - | $6,943 | 2 | $38,382 | Sep 29 | The World According to Shorts | false |
| 3 | The Social Network | - | - | - | $81,446,632 | 2,921 | $96,962,694 | Oct 1 | Sony Pictures Releasing | false |
| 20 | Case 39 | - | - | - | $13,111,685 | 2,212 | $13,261,851 | Oct 1 | Paramount Vantage | false |
